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Numerous studies have investigated the effect of individual cardiovascular risk factors, including older age, diabetes , hypertension , smoking, and hypercholesterolemia , on dementia risk, with mixed results
Numerous studies have investigated the effect of individual cardiovascular risk factors, including older age, diabetes , hypertension , smoking, and hypercholesterolemia , on dementia risk, with mixed results
Previously used the Framingham General Cardiovascular Risk Score (FGCRS), a predictive algorithm to assess cardiovascular risk burden and risk of developing cardiovascular disease by combining demographics (i.
Currently, little is known about how prior vascular risk factor (VRF) status affects brain health in later life
Currently, little is known about how prior vascular risk factor (VRF) status affects brain health in later life
RESULTS : African Americans exhibited baseline cardiovascular risk factors, incidence of aging and dementia (CAIDE), Framingham Stroke Risk Profile (FSRP), and atherosclerotic cardiovascular disease risk compared with whites Estimated (ASCVD) score was higher
Higher baseline VRF scores were associated with lower cortical thickness and larger WMH volume, whereas FSRP and CAIDE were associated with Aβ
The findings suggest that the interaction of multiple vascular and Alzheimer's pathological factors underlies neurodegeneration and cognitive decline
The findings suggest that the interaction of multiple vascular and Alzheimer's pathological factors underlies neurodegeneration and cognitive decline
references:
references:Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).
Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).
https://doi.
org/10.
1002/alz.
12429 Associations among vascular risk factors, neuroimaging biomarkers, and cognition : Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).
https://doi.
org/10.
1002/alz.
12429
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