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Alzheimer & Dementia: A flexible modeling approach to biomarker-based absolute risk calculations for Alzheimer's disease

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Alzheimer's disease (AD) is a progressive neurological disease that causes brain shrinkage (atrophy) and brain cell death

To this end, neurologists from the University of Washington in the United States analyzed the longitudinal data of more than 10,000 elderly people without cognitive impairment, and modeled the five-year AD dementia risk using survival analysis, aiming to find a calculation method

The researchers built a demographic model and validated it on independent data to predict an area (AUC) of 0.

In summary, the study developed and validated an adaptive tool to calculate the absolute risk

References:

A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer's disease dementia.

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