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Alzheimer's disease (AD) is the most common cause of dementia, and it becomes a huge burden on patients and society
.
The risk of Alzheimer's disease can be influenced by genetic and environmental factors
2019, WHO issued a prevention of cognitive decline and dementia guidelines , including smoking cessation intervention, physical activity interventions, social activities, interventions and alcohol use disorders
.
Estimates show that more than one-third of dementia cases can be prevented if the currently identified modifiable risk factors are eliminated at the population level
Prevention guide
Cerebrospinal fluid (CSF) β-amyloid protein 1-42 (Aβ42), total tau and phosphorylated tau (p-tau) are effective biomarkers of AD
.
The biomarkers of AD may have been abnormal more than 20 years before the diagnosis of dementia
In this way, Yu Jintai and others from Fudan University explored common healthy life>
.
They conducted a study on 1108 individuals with complete cognition in the Chinese Alzheimer's Disease Biomarker and Life>
.
According to life>
They found that among the cognitively intact elderly, those with more social participation had lower CSF tau (p = 0.
009) and p-tau (p <0.
001) than those with social isolation
Regular physical activity was associated with higher CSF Aβ42 (p = 0.
013) and lower CSF tau (p = 0.
036) and p-tau (p = 0.
007)
.
However, no significant associations were found between smoking status or alcohol intake and CSF biomarkers
.
When the participants’ overall life>good life>
.
.
These findings indicate that a healthy life>
.
.
Original source:
Hou XH, Xu W, Bi YL, et al.
Associations of healthy life> _Alz Res Therapy_.
2021;13(1):81.
Associations of healthy life>Leave a message here
