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Pioneer Pharmaceuticals announced that the National Medical Products Administration (NMPA) of China has recently approved its ALK-1 monoclonal antibody (GT90001C), and Bristol-Myers Squibb's (BMS) anti-PD-1 monoclonal antibody nivolumab (English trade name Opdivo) Combined clinical trial for the treatment of patients with advanced hepatocellular carcinoma (HCC) who have not been systemically treated
Liver cancer is the fourth most common cancer in China and the second most fatal cancer.
The Phase 2 clinical trial of ALK-1 monoclonal antibody/nivolumab combination therapy for the second-line treatment of patients with advanced hepatocellular carcinoma was first launched in 2019
Reference materials:
[1] Kintor Pharma Announces China NMPA Approves Clinical Trial of ALK-1 and Nivolumab Combination Therapy for the First-line Treatment of Advanced Hepatocellular Carcinoma.
[2] The clinical trial of the first-line treatment of advanced hepatocellular carcinoma with the combination of ALK-1 monoclonal antibody and O drug by Kaixing Pharmaceutical was approved by the China Food and Drug Administration.
(The original text has been deleted)