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Aging of the eyes indicates the risk of kidney failure

 Last Update: 2023-01-01
 Source: Internet
 Author: User

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Image: Retinal age gap is significantly associated with ESKD events and may be a promising non-invasive biomarker for ESKD events
.
"Correlation between Retinal Age Gap and Risk of Renal Failure: A UK Biobank Study" Visual Abstract, by Shiran Zhang and Ruiye Chen, et al.
, AJKD (2022)

In 35,864 UK residents, each year increase in retinal age (as assessed by retinal microvascular changes) was associated with a 10%
increased risk of developing renal failure at 11 years of follow-up.

Given the high morbidity and mortality associated with renal failure, there is an urgent need to identify early predictive biomarkers of renal failure
.
Aging biomarkers have been associated with renal failure, but their clinical application has been challenging
.
The study, recently published in the American Journal of Nephrology (AJKD) in UK residents, states that retinal age gap (retinal predicted age minus chronological age) is a clinically validated and AI-driven biomarker of aging based on retinal imaging that is associated with
the risk of future renal failure.
This non-invasive and aging biomarker may hold promise in helping identify people
at high risk of kidney failure.

Essay:

Association of Retinal Age Gap and Risk of Kidney Failure: A UK Biobank Study

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