Aging: A clinical trial that uses diet and lifestyle to reverse epigenetic age

Aging published "The use of diet and life>

The whole genome DNA methylation analysis of saliva samples was performed using Illumina methylation Epic Array, and DNAmAge was calculated using Horvath's online DNAmAge clock (also published in "Aging" magazine)

Compared with the control group, diet and life>

The dnnamage of the treatment group decreased by 1.

This randomized controlled study published in the journal Aging shows that specific diet and life>

This randomized controlled study published in the journal Aging shows that specific diet and life>

The lead author of the study, Kara Fitzgerald ND IFMCP from the Institute of Functional Medicine, said: “Old age is the greatest risk factor for impaired mental and physical function and many non-communicable diseases, including cancer, neurodegeneration, type 2 diabetes and diabetes.

The methylation clock is based on systemic methylation changes with age

The dnnamage clock shows that with age, about 60% of CpG sites lose methylation and 40% of CpG sites gain methylation

Nearly a quarter of DNAmAge CpG sites are located in the glucocorticoid response element, which indicates a possible relationship between stress and accelerated aging

Other findings include that post-traumatic stress disorder helps to accelerate the age of methylation; and this greater infant suffering is related to underdevelopment and younger epigenetic age

This means that the authors initially accepted the hypothetical methylation pattern calculation.

The Fitzgerald research team concluded in their aging research results: "Possibly emerging'omics' methods continue to develop our understanding of biological age prediction and reversal, not just DNA methylation

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