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These cell sensors detect subtle changes in blood pressure and adjust hormone levels to control blood pressure
The new findings of Maria Luisa S.
"It is exciting to discover that the elusive mechanism of pressure sensing, baroreceptors, is inherent to renin cells, and it has the ability to sense and respond within the same cell," said the director of UVA's Pediatrics and UVA's Children's Health Research Center.
Sensing blood pressure
The pressure sensor in the renin cells was first proposed in 1957
Sequela-Lopez and her team have adopted a new method to solve this decades-old puzzle
Researchers have accurately solved the working principle of baroreceptors
Eventually, when the baroreceptor detects that the extracellular pressure of renin is too high, the production of renin is limited, and too low blood pressure will promote the production of more renin
"I am very excited about this discovery.
Journal Reference :
Hirofumi Watanabe, Brian C.