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    Home > Active Ingredient News > Study of Nervous System > ADDADM: Eye changes may indicate early Alzheimer's disease

    ADDADM: Eye changes may indicate early Alzheimer's disease

    • Last Update: 2021-04-28
    • Source: Internet
    • Author: User
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    2021319//---,··,。,。

    《Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring》。

    (:Www.
    pixabay.
    com)

    ,·,Amir Kashani:“,。
    13,3。1%。
    (OCTA),,。。
    ,。,。,。
    ,,。,,,。( Bioon.
    com)
    :com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    :Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162




    (:Www.
    pixabay.
    com)

    ,·,Amir Kashani:“,。
    The study involved 13 people with a rare hereditary early-onset Alzheimer's disease, which is characterized by the discovery of mutations in three genes.
    This form of familial Alzheimer's disease affects 1% of patients with this disease.
    The researchers used an imaging technique called optical coherence tomography angiography (OCTA) to take images of blood vessels at the back of the eyes of study participants, regardless of whether there are mutations that cause familial Alzheimer's disease.
    They also listed the stages of the disease for people with Alzheimer's disease and the cognitive abilities of the two groups.
    The research team found that abnormal blood flow through the smallest blood vessels in the back of the eye is associated with the mutation status of subjects at risk of familial Alzheimer's disease.
    Patients with Alzheimer's mutations who have no signs of causing disease have abnormally high and heterogeneous blood flow in retinal capillaries.
    Researchers believe that this may be a sign of early inflammatory changes in the pathogenesis of Alzheimer's disease.
    The researchers say these data support the belief that eye changes can prove the earliest signs of brain disease before symptoms appear.
    Over time, with further evidence from a wider range of studies, they believe that this method can provide clinicians with tools for early diagnosis and enable interventions to slow down the cognitive decline of patients.
    (Bioon.
    com)
    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    (Image source: www.
    pixabay.
    com)

    ,·,Amir Kashani:“,。
    13,3。1%。
    (OCTA),,。。
    ,。,。,。
    ,,。,,,。( Bioon.
    com)
    :com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162


    The study involved 13 people with a rare hereditary early-onset Alzheimer's disease, which is characterized by the discovery of mutations in three genes.
    This form of familial Alzheimer's disease affects 1% of patients with this disease.
    The researchers used an imaging technique called optical coherence tomography angiography (OCTA) to take images of blood vessels at the back of the eyes of study participants, regardless of whether there are mutations that cause familial Alzheimer's disease.
    They also listed the stages of the disease for people with Alzheimer's disease and the cognitive abilities of the two groups.
    The research team found that abnormal blood flow through the smallest blood vessels in the back of the eye is associated with the mutation status of subjects at risk of familial Alzheimer's disease.
    Patients with Alzheimer's mutations who have no signs of causing disease have abnormally high and heterogeneous blood flow in retinal capillaries.
    Researchers believe that this may be a sign of early inflammatory changes in the pathogenesis of Alzheimer's disease.
    The researchers say these data support the belief that eye changes can prove the earliest signs of brain disease before symptoms appear.
    Over time, with further evidence from a wider range of studies, they believe that this method can provide clinicians with tools for early diagnosis and enable interventions to slow down the cognitive decline of patients.
    (Bioon.
    com)
    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    The researchers used an imaging technique called optical coherence tomography angiography (OCTA) to take images of blood vessels at the back of the eyes of study participants, regardless of whether there are mutations that cause familial Alzheimer's disease.
    They also listed the stages of the disease for people with Alzheimer's disease and the cognitive abilities of the two groups.
    The research team found that abnormal blood flow through the smallest blood vessels in the back of the eye is associated with the mutation status of subjects at risk of familial Alzheimer's disease.
    Patients with Alzheimer's mutations who have no signs of causing disease have abnormally high and heterogeneous blood flow in retinal capillaries.
    Researchers believe that this may be a sign of early inflammatory changes in the pathogenesis of Alzheimer's disease.
    The researchers say these data support the belief that eye changes can prove the earliest signs of brain disease before symptoms appear.
    Over time, with further evidence from a wider range of studies, they believe that this method can provide clinicians with tools for early diagnosis and enable interventions to slow down the cognitive decline of patients.
    (Bioon.
    com)
    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    The research team found that abnormal blood flow through the smallest blood vessels in the back of the eye is associated with the mutation status of subjects at risk of familial Alzheimer's disease.
    Patients with Alzheimer's mutations who have no signs of causing disease have abnormally high and heterogeneous blood flow in retinal capillaries.
    Researchers believe that this may be a sign of early inflammatory changes in the pathogenesis of Alzheimer's disease.
    The researchers say these data support the belief that eye changes can prove the earliest signs of brain disease before symptoms appear.
    Over time, with further evidence from a wider range of studies, they believe that this method can provide clinicians with tools for early diagnosis and enable interventions to slow down the cognitive decline of patients.
    (Bioon.
    com)
    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    The researchers say these data support the belief that eye changes can prove the earliest signs of brain disease before symptoms appear.
    Over time, with further evidence from a wider range of studies, they believe that this method can provide clinicians with tools for early diagnosis and enable interventions to slow down the cognitive decline of patients.
    (Bioon.
    com)
    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162

    Source of information: com/news/2021-03-eye-early-alzheimer-disease.
    html">Changes in the eye may offer early warning for Alzheimer's disease
    Original source: Maxwell B.
    Singer et al.
    onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (2021).
    DOI: 10.
    1002/dad2.
    12162
    Original Source: onlinelibrary.
    wiley.
    com/doi/10.
    1002/dad2.
    12162">Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
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