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ACR 2021: What will happen to patients with rheumatoid arthritis "bumping" on ANCA positive and vasculitis?

 Last Update: 2021-12-01
 Source: Internet
 Author: User

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Background / Objective: Anti-neutrophil cytoplasmic antibody (ANCA-) correlation vascular inflammation (AAV) and rheumatoid arthritis rarely (RA) reported

Background/Objective: Vascular Rheumatoid Arthritis

Methods: In this retrospective study, a cohort of RA+ANCA positive patients evaluated at an academic center was included

Method: Diagnose

Results: The study included 77 patients with a mean (±SD) age of 60.

result:

25 patients (32%) were diagnosed with AAV; 9 (36%) microscopic polyangiitis (MPA), 8 (32%) granuloma with polyangiitis (GPA), 1 (4%) eosinophilic granuloma With polyangiitis (EGPA), 1 (4%) GPA and rheumatoid vasculitis (peripheral ulcerative keratitis, scleritis, sudden hearing loss, MPO positive)

The diagnosis of RA precedes vasculitis in 92% of cases, occurs simultaneously in 4% of cases, and occurs after vasculitis in 4% of cases

The comparison between RA+AAV patients and RA+ANCA patients without AAV is shown in Table 2

immunity

Conclusion: The AAV in RA includes several cases of eosinophilic granuloma with polyangiitis and microscopic polyangiitis

Conclusion: The diagnosis of RA almost always precedes the diagnosis of AAV.

O'Brien C, Ranganath V, Kermani T.

Arthritis Rheumatol.

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