Absorption and metabolism of sucrose polyester

2015-01-27 classification: function 0 people commented that sucrose polyester is the trade name of fatty acid sucrose polyester (SPE), which is a fat substitute It has the taste of fat, but it can not be digested by human body and does not provide energy It can be applied in high temperature, medium temperature, low temperature and other environments, and it is suitable for the processing of fried and baked food As sucrose polyester is not decomposed and absorbed by human body, it will not provide any energy to human body The total energy absorbed by human body is an important factor to cause weight change, so the effect of sucrose polyester on weight loss is significant The oil entering the machine body can form small fat droplets (oil phase) through emulsification After mixing with bile and other digestive liquid (water phase), the solubility increases, and then it can be hydrolyzed to fatty acids and monoglycerides by lipase During the hydrolysis of triglycerides, the oil phase finally disappeared and the related components were absorbed after being transferred into the water phase If the oil phase cannot be hydrolyzed and effectively absorbed, it can only be discharged from the intestine Different esterified products of sucrose were used to test the balance of digestion and absorption in mice The results show that the hydrolysis rate of 1-3 ester is very fast, 4-5 ester is slow obviously, while 6-8 ester is hardly hydrolyzed The accumulative absorption rate of the mice was 88% glyceride, 67% erythritol, 24% xylitol and 2% sucrose ester in 24 hours These results show that with the increase of the number of ester groups in the molecule, the absorbability decreases Those with more than 3 ester groups cannot be completely absorbed, and those with 6-8 ester groups cannot be completely absorbed When 16% sucrose polyester was fed to mice, it was found that the pancreas could only treat sucrose polyester as an unusable non nutritive component and could not be fermented by the intestinal microflora as a carbon source under the condition of anoxia R.W Fsllat et al (1976) analyzed the sucrose fatty acid polyesters in the diet and feces of the subjects by high performance gel chromatography It was found that sucrose fatty acids polyesters in the residual excrement accounted for more than 97% of the dietary content Another human experiment showed that the emptying time of sucrose polyester was the same as that of water Sucrose polyester has an effect on the absorption of some substances in vivo Sucrose polyester can dissolve cholesterol and fat soluble vitamins and prevent human body from absorbing them, but it does not affect the absorption of water-soluble vitamins, proteins, carbohydrates or fats It is reported that the absorption of vitamin A and vitamin E can be significantly inhibited by adding sucrose polyester to the diet of normal and high cholesterol lipoprotein men, with inhibition rates of 10% and 21%, respectively After suspension of sucrose polyester intake for 10 days, vitamin A and vitamin E in plasma returned to their original levels Further research shows that sucrose polyester can also affect the absorption of vitamin D and vitamin K The study also found that sucrose polyester can reduce the absorption of toxic substances (such as DDT, dichlorodiphenyltrichloroethane) and promote its excretion High doses of sucrose polyester can cause diarrhea For example, if the human body ingests 150g sucrose polyester once, whether it replaces the same amount of traditional edible oil or directly adds it to the diet, it will cause diarrhea In mice, the introduction of palmitic acid or other long-chain saturated fatty acids to adjust the structure of sucrose polyester can prevent diarrhea When sucrose polyester was prepared from hydrogenated palm oil, even if the dosage was 50g / D, diarrhea would not be caused.