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    Home > Active Ingredient News > Study of Nervous System > A tired brain accumulates a lot of potential toxins!

    A tired brain accumulates a lot of potential toxins!

    • Last Update: 2022-09-09
    • Source: Internet
    • Author: User
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    ▎Edited by WuXi AppTec Content Team



    Image credit: 123RF


    ▲ Magnetic resonance spectroscopy shows that the prefrontal cortex (PFC) is susceptible to glutamate accumulation during cognitive fatigue (Image source: Reference [1])



    A more important difference was reflected in the brains of the two groups
    .

    The researchers used magnetic resonance spectroscopy (MRS) to monitor metabolites in the brains of two groups of people and found that after hours of intense mental stress in the first group, their prefrontal cortex, which is important for higher cognitive functions such as memory and decision-making, was In a very important area of ​​the brain, the concentration of glutamate produced by neural activity was higher at neural connections (ie, synapses) than in the second group
    .
    This change means that it becomes difficult for the brain to make cognitive control at this time, which is what we perceive as "brain motionless"
    .

    Given this, the researchers recommend avoiding important decisions when the brain is fatigued
    .
    So what is the best way to help the brain recover from cognitive fatigue at this time? Dr.
    Pessiglione's advice: rest, sleep!
    "There is good evidence that glutamate is eliminated from synapses during sleep, " he said
    .
    Source of cover image: 123RF References: [1] Wiehler et al.
    , (2022) A neuro-metabolic account of why daylong cognitive work alters the control of economic decisions.
    Current Biology.
    Doi: https://doi.
    org/10.
    1016 /j.
    cub.
    2022.
    07.
    010 [2] Why thinking hard makes you tire.
    Retrieved Aug.
    22, 2022 from
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