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?10 Nature: Revealing mitochondrial sub-selecting and assembly complex mechanism doi:10.10." 1038/s41586-020-03113-7 Mitochondrials are vital to the human body as a cellular energy factory: they have more than 1,000 different proteins that are necessary for many central metabolic pathways.
dysfunction of mitochondrials can lead to serious diseases, especially neurological and heart diseases.
to transport proteins and metabolites, mitochondrials contain a special set of so-called β-barrel membrane proteins, which form transport holes in the outer membrane of the mitochondrial.
, scientists have been unable to explain the β and assembly that drive these protein-barrel membrane organisms