A real hammer! High doses of vitamin C have been shown in the journal Science to enhance cancer immunotherapy!

March 2, 2020 / / -- A team of researchers from several Italian institutions has found that giving cancerous mice high doses of vitamin C (astroviric acid) can enhance immunotherapy and thus slow or stop tumor growth.
their paper, published in the journal Science Translational Medicine, researchers describe their study of vitamin C and how it can be used to treat cancer patients.
Photo Source: Science Translational Medicine As early as the 1970s, medical researchers suspected that giving cancer patients high doses of vitamin C might help reduce tumor growth, but subsequent studies failed to find any benefits and researchers lost interest.
interest in treating cancer patients with vitamin C has picked up in recent years, as research has found that early researchers gave patients oral vitamin C.
the gut does not absorb large amounts of vitamin C, which means that early patients do not get enough high doses of vitamin C to have an impact.
the new study, as part of immunotherapy, researchers injected vitamin C directly into the veins of the experimental mice and then monitored tumor growth.
found that adding high doses of vitamin C without immunotherapy possible delayed tumor growth in laboratory mice.
when it was given to mice as part of immunotherapy, they found that it slowed or stopped the growth of melanoma, colorectal cancer, pancreatic cancer and breast cancer tumors.
, they found that it was achieved by supporting T cells.
also found that vitamin C increased the effectiveness of PD-1 and CTLA-4 checkpoint antibodies.
found that in some cases, adding vitamin C to immunotherapy can cause some breast cancer tumors to disappear altogether.
that the main obstacle to treating human cancer patients with vitamin C is the possibility of side effects.
they noticed that they gave the test mice a daily level of vitamin C in an orange for several days.
if it were converted into humans, it would mean eating 2,000 oranges a day for a period of time.
() Reference: Alessandro Magr? et al. High-dose vitamin C enhances cancer immunotherapy, Science Translational Medicine (2020). DOI: 10.1126/scitranslmed.aay8707.