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Objective : To determine whether intensive serum uric acid-lowering therapy improves bone erosion scores in patients with erosive go.
Objectives : To determine whether intensive serum uric acid-lowering therapy can improve bone erosion scores in patients with erosive go.
Methods : The research team conducted a 2- year double-blind randomized controlled trial of 104 participants with erosive gout who were receiving oral urate-lowering therapy and had a baseline serum uric acid level ≥ 30 mM/.
Methods The research team conducted a 2- year , double-blind, randomized controlled trial of 104 participants with erosive gout who were receiving oral urate-lowering therapy and had baseline serum uric acid levels ≥ 30 mM /.
Results Although serum uric acid levels in the intensive target group were significantly lower than those in the standard target group during the study period ( P=002 ), fewer participants in the intensive target group achieved randomized serum uric acid target levels at year 2 ( 62% vs standard targe.
CONCLUSIONS: Compared with the serum uric acid target of <30 mM/L , oral urate-lowering therapy does not significantly reduce serum uric aci.
Dalbeth,.
, Doyle, AJ, Billington,.
, et al (2022), Intensive Serum Urate Lowering With Oral Urate-Lowering Therapy for Erosive Gout: A Randomized Double-Blind Controlled Tri.
Arthritis Rheumatol, 74: 1059-106
https://d.
org/11002/a.
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