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A novel RNA precision editing system independent of gRNA

 Last Update: 2022-09-08
 Source: Internet
 Author: User

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On August 27, 2022, the team of Wang Zefeng from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences published a long article Programmable RNA base editing with a single gRNA-free enzyme in the journal Nucleic Acids Research

Overall, REWIRE provides a single-base RNA platform for a single human protein component without the use of gRNA.

Dr.

Article link: https://academic.

Figure: REWIRE system and its optimization strategy

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