-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Meiosis is a special type of cell division that occurs in the ovaries and testes, and produces eggs and sperm by reducing the number of chromosomes to half
Professor Hiroshi Ishiguro’s team at the Institute of Molecular Embryology and Genetics (IMEG) at Kumamoto University previously discovered the meiosis gene (meosin), which turns on meiosis and causes Hundreds of genes involved in sperm and egg formation are activated simultaneously
After the function of the mouse ZFP541 gene was eliminated by genome editing, male germ cells began to meiosis, but died because they did not produce sperm, leading to infertility
In addition, ZFP541 is expressed in the early and late stages of meiosis and binds to the regulatory regions (called promoters) of many meiosis-related genes
Dr.
The researchers also believe that their research can be applied to the development of infertility treatment technologies
Journal Reference :
Yuki Horisawa-Takada, Chisato Kodera, Kazumasa Takemoto, Akihiko Sakashita, Kenichi Horisawa, Ryo Maeda, Ryuki Shimada, Shingo Usuki, Sayoko Fujimura, Naoki Tani, Kumi Matsuura, Tomohiko Akiyama, Atsushi Suzuki, Hitoshi Niachi, Takashi Niwa, Mako Hidetaka Katabuchi, Satoshi H.
