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▎The fresh breath, warm smile, white teeth and healthy gums of WuXi AppTec's content team are the main reasons why we brush our teeth every day
.
If brushing your teeth also helps promote brain health, do you think this is a fantasy? In the eyes of scientists, this is very possible
.
Professor Ryan T.
Demmer of Epidemiology at the University of Minnesota in the United States said: “Oral health triggers reactions in other parts of the body, which surprises people!” In the human mouth, there are at least 700 different kinds of “living”.
Kinds of bacteria
.
There are good and bad, and some of these bacteria can cause gum disease and other types of infections
.
More and more studies have shown that gum disease and infections are related to the health of other parts of the body, including the brain and heart
.
Image source: 123RF Oral health affects the risk of dementia In 2020, a study published in Neurology led by Professor Demmer showed that people with gum disease are more likely to suffer from gum disease than middle-aged and elderly people without gum disease Suffering from dementia; especially those with serious oral infections that cause all teeth to fall out, suffer more damage to the brain health, and the risk of dementia is nearly doubled
.
The study led by Professor Demmer analyzed data from the Atherosclerosis Risk (ARIC) cohort study in community populations.
A total of 8275 participants aged 45-64 were included, and their average age was 63.
Years old; 55% are women; the average follow-up time is up to 18 years
.
After adjusting for gender, smoking, blood pressure, body mass index (BMI) and other factors, Professor Demmer found that compared with participants with dental and oral health, there were mild to moderate gum disease, severe gum disease, and cause Participants whose oral infections caused all their teeth to lose their dementia risk increased by 22%, 15%, and 90%, respectively
.
Moreover, this association between dental and oral health and dementia was stronger in participants 62 years of age and younger compared to participants over 62 years of age
.
In addition, a study led by researchers from the National Institute of Aging and published in the Journal of Alzheimer's Disease also showed that during the 26-year follow-up period, compared with oral health Of the elderly, those with gum disease have a 46% increased risk of dementia
.
Image source: 123RF Oral Health Affects Stroke Risk In 2021, a study led by a research team at Peking University and published in the European Journal of Clinical Investigation showed that frequent tooth brushing is associated with increased risk of a variety of diseases High correlation, including stroke and cerebral hemorrhage
.
The study analyzed data from the China Prospective Study of Chronic Diseases (CKB) and included a total of 487,198 participants aged 30-79; the average age was 51.
5 years; 41% were men; the average follow-up time was up to 10 years
.
After adjusting for other factors, the researchers found that compared with participants who brushed their teeth frequently, brushing their teeth rarely or never was associated with an increased risk of a variety of diseases, including an 8% increase in stroke risk and an increased risk of cerebral hemorrhage.
18%, 15% increased risk of myocardial infarction, 22% increased risk of pulmonary heart disease, 9% increased risk of cancer, 12% increased risk of chronic obstructive pulmonary disease, and 25% increased risk of liver cirrhosis
.
In addition, in 2019, a research team from Tampere University in Finland published a study in the Journal of the American Heart Association.
The results showed that common cerebral thrombosis was found in stroke patients.
Signs of oral bacteria! This means that in addition to inflammation, bacteria may also be involved in the formation of blood clots
.
Image source: Why does 123RF oral health affect brain health? Scientists analyze that with age, the balance of good and bad bacteria in the mouth will change, creating an environment that is more prone to gum disease and other infections, which are related to dementia, stroke, type 2 diabetes and the heart Related to increased risk of diseases such as disease
.
Professor Demmer said that there are some speculations about the biological mechanisms of oral health and brain health, but they have not yet been fully confirmed
.
Most scientists believe that systemic inflammation is the link that connects oral and brain health
.
The imbalance between good and bad bacteria in the oral cavity can cause bad bacteria to be sent into the bloodstream, trigger an immune response, and produce low-grade, systemic inflammation
.
Inflammation plays an important role in the occurrence of dementia, stroke and heart disease
.
Some scientists also believe that the association between oral and brain health may be related to the reduction of good bacteria in the mouth and intestines
.
These good bacteria can convert dietary nitrate (found in leafy foods) into nitric oxide, and nitric oxide helps maintain good blood vessel health and lower blood pressure
.
But as we age, the number of good bacteria in the oral cavity decreases.
There may not be enough good bacteria to convert nitrate into nitric oxide, leading to high blood pressure, which increases the risk of diseases such as dementia, stroke and heart disease
.
Image source: What should 123RF do to promote oral health? Professor Demmer said that more and more studies have shown that oral health and brain health are closely related, and one of the effective ways to promote oral health is to brush your teeth frequently, and it is best to brush your teeth twice in the morning and evening to remove the surface of the teeth.
Food residues to prevent periodontal disease and other types of infections
.
The "Oral Health Guide for Chinese Residents" also pointed out that oral health is the basic recommendation for general health.
To promote oral health, brush your teeth in the morning and evening, rinse your mouth after meals, and brush your teeth at least twice a day; A toothbrush and a mouth cup should be placed separately for each person to avoid cross-infection; the use of health-care toothbrushes (referring to toothbrushes that meet the hygiene standards of oral health and can effectively remove dental plaque) is recommended, and be replaced in time; use dental floss or Interdental brushing helps to clean the gap between teeth; choose toothpaste according to the needs of oral health, and advocate the use of fluoride toothpaste to prevent caries; eat sugar scientifically and drink less sugary beverages; smoking is harmful to oral health, so you should quit smoking as soon as possible
.
In addition, oral health checkups should be performed at least once a year; teeth cleaning (washing) should be performed once a year
.
When symptoms such as mouth discomfort, pain, bleeding gums, or peculiar smell appear in the mouth, seek medical advice in time; repair missing teeth in time
.
At the same time, select medical institutions with qualifications for oral health care and treatment
.
Recommended reading God! The products you eat and use every day may be "toxic"? Nearly one-third of Chinese people have the disease, which may double the risk of breast cancer! How to prevent the coexistence of this disease! Cancer survivors should be vigilant.
More than 40% of 5 Chinese people suffer from multiple chronic diseases, and 2 of them will suffer from this disease! How to quickly identify and prevent? "Anita Mui" is on the hot search again: If every woman had cervical cancer prevention and screening earlier, maybe.
.
.
Reference materials[1] Ryan T.
Demmer1, et al.
,(2020).
Periodontal Disease and Incident Dementia: The Atherosclerosis Risk in Communities Study (ARIC).
Neurology, DOI: 10.
1212/WNL.
0000000000010312.
[2] Beydoun, et al.
,(2020).
Clinical and Bacterial Markers of Periodontitis and Their Association with Incident All-Cause and Alzheimer's Disease Dementia in a Large National Survey.
Journal of Alzheimer's Disease, DOI: 10.
3233/JAD-200064.
[3] Zhenhuang Zhuang, et al.
,(2021).
Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults.
European Journal of Clinical Investigation, DOI: https://doi.
org/10.
1111/eci.
13634.
[4] Olli Patrakka, et al.
, (2019). .
This article is for the purpose of information exchange only.
The opinions expressed in the article do not represent the position of WuXi AppTec, nor does it mean that WuXi AppTec supports or opposes the views in the article
.
This article is not a treatment recommendation either
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
.
If brushing your teeth also helps promote brain health, do you think this is a fantasy? In the eyes of scientists, this is very possible
.
Professor Ryan T.
Demmer of Epidemiology at the University of Minnesota in the United States said: “Oral health triggers reactions in other parts of the body, which surprises people!” In the human mouth, there are at least 700 different kinds of “living”.
Kinds of bacteria
.
There are good and bad, and some of these bacteria can cause gum disease and other types of infections
.
More and more studies have shown that gum disease and infections are related to the health of other parts of the body, including the brain and heart
.
Image source: 123RF Oral health affects the risk of dementia In 2020, a study published in Neurology led by Professor Demmer showed that people with gum disease are more likely to suffer from gum disease than middle-aged and elderly people without gum disease Suffering from dementia; especially those with serious oral infections that cause all teeth to fall out, suffer more damage to the brain health, and the risk of dementia is nearly doubled
.
The study led by Professor Demmer analyzed data from the Atherosclerosis Risk (ARIC) cohort study in community populations.
A total of 8275 participants aged 45-64 were included, and their average age was 63.
Years old; 55% are women; the average follow-up time is up to 18 years
.
After adjusting for gender, smoking, blood pressure, body mass index (BMI) and other factors, Professor Demmer found that compared with participants with dental and oral health, there were mild to moderate gum disease, severe gum disease, and cause Participants whose oral infections caused all their teeth to lose their dementia risk increased by 22%, 15%, and 90%, respectively
.
Moreover, this association between dental and oral health and dementia was stronger in participants 62 years of age and younger compared to participants over 62 years of age
.
In addition, a study led by researchers from the National Institute of Aging and published in the Journal of Alzheimer's Disease also showed that during the 26-year follow-up period, compared with oral health Of the elderly, those with gum disease have a 46% increased risk of dementia
.
Image source: 123RF Oral Health Affects Stroke Risk In 2021, a study led by a research team at Peking University and published in the European Journal of Clinical Investigation showed that frequent tooth brushing is associated with increased risk of a variety of diseases High correlation, including stroke and cerebral hemorrhage
.
The study analyzed data from the China Prospective Study of Chronic Diseases (CKB) and included a total of 487,198 participants aged 30-79; the average age was 51.
5 years; 41% were men; the average follow-up time was up to 10 years
.
After adjusting for other factors, the researchers found that compared with participants who brushed their teeth frequently, brushing their teeth rarely or never was associated with an increased risk of a variety of diseases, including an 8% increase in stroke risk and an increased risk of cerebral hemorrhage.
18%, 15% increased risk of myocardial infarction, 22% increased risk of pulmonary heart disease, 9% increased risk of cancer, 12% increased risk of chronic obstructive pulmonary disease, and 25% increased risk of liver cirrhosis
.
In addition, in 2019, a research team from Tampere University in Finland published a study in the Journal of the American Heart Association.
The results showed that common cerebral thrombosis was found in stroke patients.
Signs of oral bacteria! This means that in addition to inflammation, bacteria may also be involved in the formation of blood clots
.
Image source: Why does 123RF oral health affect brain health? Scientists analyze that with age, the balance of good and bad bacteria in the mouth will change, creating an environment that is more prone to gum disease and other infections, which are related to dementia, stroke, type 2 diabetes and the heart Related to increased risk of diseases such as disease
.
Professor Demmer said that there are some speculations about the biological mechanisms of oral health and brain health, but they have not yet been fully confirmed
.
Most scientists believe that systemic inflammation is the link that connects oral and brain health
.
The imbalance between good and bad bacteria in the oral cavity can cause bad bacteria to be sent into the bloodstream, trigger an immune response, and produce low-grade, systemic inflammation
.
Inflammation plays an important role in the occurrence of dementia, stroke and heart disease
.
Some scientists also believe that the association between oral and brain health may be related to the reduction of good bacteria in the mouth and intestines
.
These good bacteria can convert dietary nitrate (found in leafy foods) into nitric oxide, and nitric oxide helps maintain good blood vessel health and lower blood pressure
.
But as we age, the number of good bacteria in the oral cavity decreases.
There may not be enough good bacteria to convert nitrate into nitric oxide, leading to high blood pressure, which increases the risk of diseases such as dementia, stroke and heart disease
.
Image source: What should 123RF do to promote oral health? Professor Demmer said that more and more studies have shown that oral health and brain health are closely related, and one of the effective ways to promote oral health is to brush your teeth frequently, and it is best to brush your teeth twice in the morning and evening to remove the surface of the teeth.
Food residues to prevent periodontal disease and other types of infections
.
The "Oral Health Guide for Chinese Residents" also pointed out that oral health is the basic recommendation for general health.
To promote oral health, brush your teeth in the morning and evening, rinse your mouth after meals, and brush your teeth at least twice a day; A toothbrush and a mouth cup should be placed separately for each person to avoid cross-infection; the use of health-care toothbrushes (referring to toothbrushes that meet the hygiene standards of oral health and can effectively remove dental plaque) is recommended, and be replaced in time; use dental floss or Interdental brushing helps to clean the gap between teeth; choose toothpaste according to the needs of oral health, and advocate the use of fluoride toothpaste to prevent caries; eat sugar scientifically and drink less sugary beverages; smoking is harmful to oral health, so you should quit smoking as soon as possible
.
In addition, oral health checkups should be performed at least once a year; teeth cleaning (washing) should be performed once a year
.
When symptoms such as mouth discomfort, pain, bleeding gums, or peculiar smell appear in the mouth, seek medical advice in time; repair missing teeth in time
.
At the same time, select medical institutions with qualifications for oral health care and treatment
.
Recommended reading God! The products you eat and use every day may be "toxic"? Nearly one-third of Chinese people have the disease, which may double the risk of breast cancer! How to prevent the coexistence of this disease! Cancer survivors should be vigilant.
More than 40% of 5 Chinese people suffer from multiple chronic diseases, and 2 of them will suffer from this disease! How to quickly identify and prevent? "Anita Mui" is on the hot search again: If every woman had cervical cancer prevention and screening earlier, maybe.
.
.
Reference materials[1] Ryan T.
Demmer1, et al.
,(2020).
Periodontal Disease and Incident Dementia: The Atherosclerosis Risk in Communities Study (ARIC).
Neurology, DOI: 10.
1212/WNL.
0000000000010312.
[2] Beydoun, et al.
,(2020).
Clinical and Bacterial Markers of Periodontitis and Their Association with Incident All-Cause and Alzheimer's Disease Dementia in a Large National Survey.
Journal of Alzheimer's Disease, DOI: 10.
3233/JAD-200064.
[3] Zhenhuang Zhuang, et al.
,(2021).
Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults.
European Journal of Clinical Investigation, DOI: https://doi.
org/10.
1111/eci.
13634.
[4] Olli Patrakka, et al.
, (2019). .
This article is for the purpose of information exchange only.
The opinions expressed in the article do not represent the position of WuXi AppTec, nor does it mean that WuXi AppTec supports or opposes the views in the article
.
This article is not a treatment recommendation either
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
