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Research led by Bristol has identified specific drug targets in the neural circuits that encode memory, paving the way for the treatment of a wide range of brain disorders
Memory loss is a core feature of many neurological and psychiatric diseases, including Alzheimer's disease and schizophrenia
This research was done in collaboration with colleagues from the international biopharmaceutical company Sosei Heptares
Professor Jack Mellor from the Synaptic Plasticity Center of the University of Bristol, the lead author of the study, said: "These findings are about the basic processes that occur in the brain during memory encoding, and how they are targeted or targeted by the brain.
Dr.
"The fascinating thing is how the brain prioritizes different information to determine which information needs to be encoded in memory and which can be discarded
'Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits,' by Palacios-Filardo, J.
10.
