A Brief Discussion on the Pharmaceutical Research of Bayberry Flavonoids

Bayberry is a plant belonging to the genus Bayberry, a perennial evergreen tree in the bayberry family.

Antioxidant activity

Studies have found that the use of 3% concentration of choline water into mice produces vascular endothelial dysfunction and liver oxidative stress.

Anti-inflammatory

Inflammation is a defense-oriented response when various damage factors act on the body.

Antibacterial activity

Studies have found that myricetin flavone can inhibit the virulence of Porphyromonas gingivalis by reducing the expression of important virulence factor-encoding genes, including proteases (rgpA, rgpB and KGP) and adhesin (FIMA).

Lipid lowering, weight loss

Studies have shown that myrica flavonoids can increase fatty acid oxidation, inhibit the increase in body mass and body fat accumulation, and achieve the effect of reducing fat and weight.

Tumor suppressor

The anti-tumor activity of bayberry flavonoids is mainly manifested in inducing tumor cell apoptosis, interfering with tumor cell signal transduction, and inhibiting tumor invasion and metastasis.

Another study found that myrica flavonoids can induce apoptosis in the ovarian cancer cell line SKOV3 by inducing DNA double-strand breaks and endoplasmic reticulum stress, which inhibits SKOV3 cell activity in a dose-dependent manner.

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Reference

[1] Li Yao, Liu Yao, Wang Zhentao, Fan Hongyan.

[2] Jiang Suxin, Lai Yongwei, Li Yao, Wang Mengnan, Zhang Xiwen, Li Lele, Zhang Qiang, Fan Hongyan.

[3] Xie Jing, Zheng Yanyan, Lu Qianqi.