7T MRI imaging detects intracranial arterial vascular wall lesions

Symptomatic intracranial atherosclerosis (intracranial atherosclerosis, ICAS) is the main cause of ischemic stroke, with high morbidity and mortalityRecent studies have shown that high-resolution MRI arterial wall imaging can directly and clearly show the atherosclerosis lesions of the intracranial arterial vascular wallMaarten HTZwartbol of the Department of Radiology at utheg University Medical Center in the Netherlands used 7T MRI intracranial arterial wall imaging to analyze the distribution and risk factors for ICAS lesions, published in The Stroke in January 2019- Excerpted from the article: Zwartbol MHT, et alStroke2019 Jan; 50 (1: 88-94doi: 10.1161/STROKEAHA.118.022509.)symptomatic intracranial atriosis alysation (intracranial atisticasRecent studies have shown that high-resolution MRI arterial wall imaging can directly and clearly show the atherosclerosis lesions of the intracranial arterial vascular wallMaarten HTZwartbol of the Department of Radiology at utheg University Medical Center in the Netherlands used 7T MRI intracranial arterial wall imaging to analyze the distribution and risk factors for ICAS lesions, published in The Stroke in January 2019the data from a prospective study of magnetic resonance manifestations of arterial disease (Second Marrs of Arterial Disease-Magnetic Resonance, SMART-MR) conducted between 2001 and 2005The distribution of the systemic arterial system and the risk factors of arterial wall damage were analyzed by linear regression, including coronary heart disease, cerebrovascular disease, peripheral vascular disease or abdominal aortic aneurysm, and with 7T MRI intracranial arterial wall imaging data analysis showed that 96% of patients had one or more vascular wall lesions in the intracranial artery The number of intracranial arterial total ICAS lesions 0 to 32, an average of 7 (Mean-SD-8.5-5.7); the number of pre-circular artery walls of ICAS lesions 0 to 14, the average number of 4 (Mean-SD-5.3-3.2); the number of post-circular artery walls ICAS lesions 0 to 18, and the average number of 3 (SD-3.8.3) figure 1 1 case of a 79-year-old male with a history of coronary heart disease, and multiple ICAS lesions of intracranial arteries were found in MRI-T1 weighted imaging A Base artery vascular wall lesions (arrows); B Left vertebral artery far endvascular wall lesions (arrows), right vertebral artery normal; C bilateral M1 vascular wall lesions (arrow s) ;D the number of intracranial arterial wall lesions was significantly correlated with age, systolic pressure, diabetes, glycifying hemoglobin levels, lipoprotein B (apoB) and hypersensitivity c-reaction protein (hs-CRP) levels (Tables 1, 2) No statistical correlation with sex, smoking history, and other lipid components other than lipoprotein B table 1 Risk factors associated with the number of ICASs in the intracranial arterial walls b value: non-standardized linear regression coefficient adjusted for age and gender; table 2 Metabolic and other risk factors associated with the number of ICAS lesions in the intracranial arterial vascular wall b value: non-standardized linear regression coefficients adjusted for age and gender , the authors believe that high-resolution MRI vascular wall imaging can detect intracranial atherosclerosis lesions The study also confirmed that ICAS is common in middle-aged and elderly patients.