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On November 23, 2021, Chongqing Gaojin Biotechnology Co.
Why is boron medicine sacred?
Why is boron medicine sacred?BNCT (Boron Neutron Capture Therapy) is one of the most advanced cancer treatments in the world
Schematic diagram of the principle of BNCT nuclear physical phenomenon (Source: Gaojin Bio official website)
Based on the above principles of nuclear physics, the treatment process of BNCT is as follows:
① Design a boron-loaded drug that can be targeted into tumor cells and can be enriched to an effective concentration in tumor cells;
② Design a technical solution that can be traced in vitro, which can grasp the tumor site reached by boron-loaded drugs in real time;
③ Use a neutron source that can generate epithermal neutron beams to irradiate the tumor site.
BNCT treatment process (source: Gaojin Bio official website)
cancer treatment
cancer treatmentThe "Pearl in the Crown" is well deserved
The "Pearl in the Crown" is well deservedThe reason why BNCT is known as the "jewel in the crown" of cancer treatment is because of its numerous advantages, which can be summarized as follows:
①High safety, no need for surgery, BNCT can "mark" cancer cells, accurately destroy the DNA of cancer cells, and cause minimal damage to surrounding cells and tissues;
②The course of treatment is short, only 1-2 times of irradiation;
③The curative effect is predictable.
④ Wide range of indications, BNCT treatment can be tried for invasive, multiple, recurrent, radiation-resistant, inoperable and unsuitable cancers;
⑤ It can be combined with a variety of carrier agents, and has great potential for development;
⑥ Avoid the drug resistance problems of chemotherapy, targeted therapy and immunotherapy;
⑦The cost of treatment is relatively low, and BNCT boron medicine can be affordable by most families
Therefore, these characteristics of BNCT make it promising to be one of the most ideal tumor treatment methods, benefiting many cancer patients
Development Status of BNCT——Industrialization is Ready to Go
Development Status of BNCT——Industrialization is Ready to Go1
1An overview of the global frontier progress
An overview of the global frontier progressAt present, Japan, Finland, the United States, China and other countries are mainly conducting research and clinical trials of BNCT
In early March 2020, the Japanese Ministry of Health, Labour and Welfare approved the clinical application of the world's first BNCT device
So far, two institutions in Japan have used BNCT to treat patients, one is at the Osaka Medical University-Kansai BNCT Center; the other is at the South Tohoku General Hospital BNCT Center
2
2Looking forward to a rising star in China
Looking forward to a rising star in ChinaIn August 2020, China's first self-developed BNCT accelerator experimental device was successfully developed, laying a technical foundation for the localization and industrialization of China's medical BNCT treatment device
BNCT boron drug may be able to produce good curative effect at lower drug cost, and is expected to provide a better choice for many cancer patients
References:
[1] http:// The cancer cells were cleared in 30 minutes, and the pilot test of the domestic anti-cancer boron drug was successful, and only 100,000 was required to have a medical insurance precedent
https://xw.
[3] China's first anti-cancer boron drug has completed the pilot test and is expected to be used in clinical practice in 2023
https://baijiahao.
[4] Precise anti-cancer technology is released! The domestic BNCT anticancer boron drug is here, and it is expected to be available in 2023
https://baijiahao.
[5] China's first anti-cancer boron drug has completed the pilot test, and can cure a variety of specific cancers in as fast as 30 minutes!
https://page.
[6] Japan's latest "cancer-killing artifact" BNCT has been approved! The treatment cost is 300,000! How is it different from proton therapy?
https://med.