2021 ACR: How reliable is it?

Bone marrow lesions (BML) and synovitis on MRI are independently related to the severity and progression of osteoarthritis (OA) .
The goal of randomized controlled trials is to reduce the size of BML and the degree of synovitis to treat OA .
The OMERACT knee joint inflammation MRI scoring system (KIMRISS) developed by researchers has recently been improved to maximize reliability and sensitivity to changes .
Innovations include custom-designed electronic overlays for touch screen interfaces, BML for evaluating 500 sub-regions on continuous sagittal slices, a web-based interface that can be directly scored online, and real-time iterative calibration (RETIC) before formal reading exercises .
The purpose of this research is to test the feasibility, reliability and responsiveness of comparing KIMRISS with the established method MOAKS in a multi-reader exercise .

Bone marrow lesions (BML) and synovitis on MRI are independently related to the severity and progression of osteoarthritis (OA) .

The goal of randomized controlled trials is to reduce the size of BML and the degree of synovitis to treat OA .
The OMERACT knee joint inflammation MRI scoring system (KIMRISS) developed by researchers has recently been improved to maximize reliability and sensitivity to changes .
Innovations include custom-designed electronic overlays for touch screen interfaces, BML for evaluating 500 sub-regions on continuous sagittal slices, a web-based interface that can be directly scored online, and real-time iterative calibration (RETIC) before formal reading exercises .
The purpose of this research is to test the feasibility, reliability and responsiveness of comparing KIMRISS with the established method MOAKS in a multi-reader exercise .

KIMRISS incorporates network-based graphical overlays of each of the femur, tibia, and patella to score the BML of 500 sub-regions on consecutive sagittal slices .

SE is the maximum diameter of the fluid signal on all consecutive sagittal slices (scoring range 0-100 ) .
All scores are calculated in proportion to the standardized number of MRI slices .
In the KIMRIISS pre-reading exercise, readers will score the RETIC module to achieve proficiency (defined as ICC ≥ 0.
80 and BML and SE status and change score ≥ 0.
70 ) .

KIMRISS incorporates network-based graphical overlays of each of the femur, tibia, and patella to score the BML of 500 sub-regions on consecutive sagittal slices .
SE is the maximum diameter of the fluid signal on all consecutive sagittal slices (scoring range 0-100 ) .
All scores are calculated in proportion to the standardized number of MRI slices .
In the KIMRIISS pre-reading exercise, readers will score the RETIC module to achieve proficiency (defined as ICC ≥ 0.

For exercise A/B , the subjects were 55.
3%/26.

Compared with MOAKS , the KIMRISS method for BML and synovitis - effusion scoring scores high in terms of feasibility and shows consistently high reliability .
For BML and SE , both methods can prove the correlation with WOMAC pain .
In the case where the MRI feature changes are greater than the OAI data set, further verification of responsiveness is needed .

Original source :

Original source

Maksymowych W, Jaremko J, Pedersen S, Eshed I, Weber U, Bird P, McReynolds A, Wichuk S, Paschke J, Lambert R.

The OMERACT Knee Inflammation MRI Scoring System: Validation of Quantitative Methodologies and Tri-compartmental Overlays by Comparison with the MRI Osteoarthritis Knee Score [abstract].
  Arthritis Rheumatol.
 2021; 73 (suppl 10).

Maksymowych W, Jaremko J, Pedersen S, Eshed I, Weber U, Bird P, McReynolds A, Wichuk S, Paschke J, Lambert R.

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