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Pro: 1 common dietary supplement that reduces the risk of 5 cancers by more than 50%! And the effect lasts for more than 10 years!
Author: Medical World Elephant
With the improvement of living standards, people are not satisfied with eating enough, eating well and eating healthy is people's pursuit
The more common dietary supplements in daily life include probiotics, vitamin C, vitamin D, and cod liver oil
For people who are unable to get enough nutrients from food, dietary supplements can be effective in replenishing deficiencies
In addition, dietary supplements have taken on new roles, especially in relation to disease prevention, including cancer
Can dietary supplements help prevent cancer?
Can dietary supplements help prevent cancer?Let's take a look at a new study published in Cancer Prevention Research
Image source: Screenshot of the official website of the journal Cancer Prevention Research
It was a 10-year, double-blind study led
From 1999 to 2005, nearly 1,000 participants began taking resistant starch, aspirin, or placebo
Take resistant starch, aspirin, or placebo in powder form daily for 2 years
The timing of follow-up of participants and the final cancer data statistics
It should be mentioned that the participants in this study were patients
Patients with Lynch syndrome
Lynch syndrome
Lynch syndromeIn 1966, Henry T.
In 1985, Professor Henry Lynch named the syndrome Hereditary nonpolyposis colorectal cancer (HNPCC).
Lynch syndrome, or hereditary nonpoposis colon cancer, is an autosomal dominant disorder caused by defects in four mis-match repair genes (MMR), namely MLH1, MSH2, MSH6, and PMS2
MLH1、MSH2、MSH6、PMS2
Lynch syndrome is not a stand-alone disease, but a syndrome capable of developing multiple tumors, colorectal cancer and endometrial cancer are the most common manifestations, Lynch syndrome accounts for 5%-15%
Lynch syndrome colorectal cancer and endometrial cancer
In addition to colorectal cancer and endometrial cancer, cancer
In addition, patients with Lynch syndrome may also have an increased
In this study, the researchers mainly studied the effects of resistant starch and aspirin on colorectal cancer and other cancers, and the results showed that aspirin and resistant starch have a cancer prevention effect
Resistant starch and aspirin Aspirin and resistant starch have the effect of preventing
cancer.
As part of this long-term study, previous studies published the results of the aspirin study: taking aspirin in the group can reduce the risk
of colorectal cancer by up to 50%.
of colorectal cancer by up to 50%.
In the newly published study, only 5 of the 463 participants who took resistant starch during the follow-up period had new cases of upper gastrointestinal cancer, corresponding to 21 new cases of upper gastrointestinal cancer among the 455 participants who took the placebo!
Only 5 of the 463 participants who took resistant starch during follow-up developed new cases of upper gastrointestinal cancerDetailed statistics on the final outcome of all patients followed
Professor John Mathers, professor of human nutrition at the University of Newcastle, said resistant starch has a preventive effect on a range of cancers, including esophageal, gastric, biliary, duoctal cancer and pancreatic cancer, the "king of cancer", which can reduce the risk of these cancers by more than
60%.
60%.
And, as the follow-up time lengthened, the researchers found that even if the dietary supplement was stopped subsequently, this preventive and protective effect could last for more than 10 years!
This preventive and protective effect can also last more than 10 years!Comparison of the cumulative risk of onset of the time at which participants taking resistant starch and placebo developed colorectal cancer and other cancers for the first time;
Blue is the placebo group and orange is the resistant starch group, and it can be seen that the resistance starch group has a lower risk of disease overall as the follow-up time is extended
What is resistant starch?
What is resistant starch?Resistant starch cannot be enzymatically digested in the small intestine, so it is also called anti-enzymatic starch, difficult to digest starch; However, it can be fermented in the large intestine, nourishing the beneficial intestinal flora in the large intestine; Resistant starch has fewer calories and more health benefits
than regular starch.
The researchers said that the anti-cancer effect of resistant starch may be related to its ability to change the bacterial metabolism of bile acids to reduce the secretion of harmful types of bile acids to protect human DNA, but this theory needs further research support
.
Which foods are rich in resistant starch?
Which foods are rich in resistant starch?9 foods containing a lot of resistant starch
9 foods containing a lot of resistant starch1.
Oats
Oats
Oats are one of the most convenient ways to add resistant starch to your
diet.
100 grams of cooked oatmeal may contain approximately 3.
6 grams of resistant starch
.
Oats are a whole grain and are also high in
antioxidants.
2.
Cooked and cooled rice
Cooked and cooled rice
Rice is another low-cost and convenient way
to add resistant starch to your diet.
Brown rice may be more popular than white rice because of its higher
fiber content.
Brown rice also provides more micronutrients such as phosphorus and magnesium
.
3.
Other grains
Other grains
Sorghum and barley, such as sorghum, provide a large amount of resistant starch
.
Grains are not only a great source of fiber, but also contain important vitamins and minerals such as vitamin B6 and selenium
.
4.
Beans
Beans
Pulses provide large amounts of fiber and resistant starch
.
Both should be soaked and heated adequately to remove lectins and other anti-nutrients
.
Beans contain approximately 1-5 grams of resistant starch
per 100 grams after cooking.
Good sources include: spotted beans, black beans, soybeans, peas;
Fava beans are an excellent source
of resistant starch.
When fried or roasted, 7.
72–12.
7 grams of resistant starch
are available per 100 g serving.
5.
Raw potato starch
Raw potato starch
Potato starch is a white powder that looks similar to regular flour
.
It is one of the most concentrated sources of resistant starch, with about 80% of starch being resistant
.
6.
Cooked and cooled potatoes
Cooked and cooled potatoes
Potatoes are a good source
of resistant starch.
It's best to cook them in large quantities and let them cool for at least a few hours, and cooked potatoes also contain a lot of resistant starch
.
In addition to being a good source of carbohydrates and resistant starch, potatoes also contain nutrients such as potassium and vitamin C, so remember not to reheat potatoes
.
7.
Green bananas
Green bananas
Both green and yellow bananas are a healthy carbohydrate and provide other nutrients such as vitamin B6, vitamin C, and fiber
.
As the banana ripens, the resistant starch is converted to a monosaccharide
.
Green bananas are rich in resistant starch, which is replaced
by monosaccharides as they ripen.
by monosaccharides as they ripen.
8.
Other cooked and cooled starchy carbohydrates
Other cooked and cooled starchy carbohydrates
Cooking and cooling other starches increases their resistant starch content
.
As with the food sources discussed above, it's best to heat them up and then let them cool overnight
.
Cooking and cooling starchy foods increases their resistant starch content
.
This is true of foods that are already high in resistant starch, as well as foods such as pasta, sweet potatoes and tortillas
.
In this study, the regular dose of resistant starch powder taken by participants for 2 years was about the same as eating a banana, and the amount of supplement was not high
.
In recent years, resistant starch has been "very hot", mainly because it can be well used for weight loss and has gained people's favor, but there may be more health benefits worth exploring
.
In fact, many foods are closely related to the health of our gut microbiota, which has been shown in recent years to have more to do with
immunomodulation.
It is believed that with more research results, it will be possible
to prevent cancer by adjusting food intake.
to prevent cancer by regulating food intake.
Further reading: Lynch syndrome
Further reading: Lynch syndromeCancer "heir": With this disease, the risk of cancer is as high as 82%!
Cancer "heir": With this disease, the risk of cancer is as high as 82%!By CellPlus
Source: CellPlus, Medical World Elephant
References:
[1] Mathers JC, Elliott F, Macrae F, Mecklin JP,et al.
Cancer Prevention with Resistant Starch in Lynch Syndrome Patients in the CAPP2-Randomized Placebo Controlled Trial: Planned 10-Year Follow-up.
Cancer Prev Res (Phila).
2022 Jul 25:OF1-OF12.
doi: 10.
1158/1940-6207.
CAPR-22-0044.
Epub ahead of print.
PMID: 35878732.
[2] First trial to prove a diet supplement can prevent hereditary cancer.
https://medicalxpress.
com/news/2022-07-trial-diet-supplement-hereditary-cancer.
html
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