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The differential diagnosis of nephrolithiasis necessary for clinical practice, don't forget these six diseases!
Time of Update: 2022-02-22
Identification: According to the patient's medical history, clinical manifestations, and determination of blood and urine amylase, most acute pancreatitis can generally be diagnosed .
When renal colic occurs in patients with right kidney stones, it should be distinguished from acute appendicitis .
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Professor Han Sujun: Research progress and direction of muscle-invasive bladder cancer
Time of Update: 2022-02-22
Research progress in cisplatin-resistant populations For cisplatin-resistant populations, four phase II studies have shown that durvalizumab + GC, atezolizumab + GC, pembrolizumab + GC, The pCR rates (pT0) of nivolumab + GC in platinum-resistant MIBC were 34%, 44%, 36%, and 34%, respectively .
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STREAM trial: Enzalutamide + ADT and salvage radiotherapy significantly effective in high-risk prostate cancer
Time of Update: 2022-02-21
3 Summary This study confirms that salvage enzalutamide and ADT combined with radiotherapy is safe 6 months after prostatectomy in patients with high-risk PSA recurrence, and the results are also shown on 2- and 3-year PFS.
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The latest CUA guidelines at a glance: 16 tips for treating ureteral stones
Time of Update: 2022-02-21
Patients with ureteral stones with a stone density >1000HU or SSD>10cm have a lower stone-free rate (SFR) after shock wave lithotripsy (grade 2, strong recommendation); treatment decisions should be discussed with the patient to balance the advantages and disadvantages of SWL vs URS, Complications and efficacy .
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Lower Urinary Tract Symptoms Caused by BPH: A New Combination Therapy More Applicable in a Small Population Expert Commentary
Time of Update: 2022-02-20
How to Avoid Prescribing Cascades Consider that patients with lower urinary tract symptoms secondary to BPH-induced BPH have more options for medications and novel surgical approaches .
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Learn the etiology, diagnosis and treatment of epididymitis in one article!
Time of Update: 2022-01-27
Introduction The epididymis is a reproductive organ located at the back of the testis and connected to the vas deferens . The epididymis can store and carry sperm . After the sperm leaves the testi
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The Light of Sinopharm: The first domestic ADC drug Vidicitumab has been approved for a new indication
Time of Update: 2022-01-27
In July 2021, the marketing application for the second indication of Vidicitumab was accepted by the NMPA Center for Drug Evaluation (CDE) and was included in priority review for patients who have received systemic chemotherapy and have HER2 (2+ or 3+) (immunohistochemical results) in patients with locally advanced or metastatic urothelial carcinoma .
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Molecular Cancer Multi-unit cooperation of Southern Medical University, Zhao Shanchao/Feng Ninghan/Chen Zhesheng discovered potential therapeutic targets for prostate cancer
Time of Update: 2022-01-27
John's University published a joint communication online in Molecular Cancer (IF=27) entitled "Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR- 653-5p", which identified differentially expressed circRNAs by RNA sequencing .
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Paper Summary: Diagnosis and Treatment of Overactive Bladder in Children
Time of Update: 2022-01-27
Combination medication: Studies have found that oral oxybutynin 5-20mg/d or tolterodine 2-4mg/d combined with low-dose solifenacin (5-10mg/d) has a good effect in the treatment of refractory OAB in children.
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The efficacy of immunotherapy lasts for more than 2 years, and the expression level of PD-L1 after chemotherapy may predict the efficacy of bladder cancer practice cases
Time of Update: 2022-01-27
This case reports a patient with locally advanced T4 bladder cancer who achieved a complete response (CR) with pembrolizumab after progression on chemotherapy and radiotherapy .
Conclusions In this case report, a patient with stage T4 locally invasive bladder cancer achieved CR with pembrolizumab after progression on chemoradiotherapy .
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Dr. Cai Yi walks with "swollen": looking back on the past and making his own voice in the field of prostate cancer
Time of Update: 2022-01-26
Insufficient existing treatment plans , insufficient patient benefits, and urgent desire of doctors to improve diagnosis and treatment methods are the driving forces that drive the continuous clinical research in the field of prostate cancer and the development and renewal of more drugs .
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my country's first ADC for the treatment of urothelial cancer is here!
Time of Update: 2022-01-26
As China's first self-developed antibody-drug conjugate (ADC) new drug, on June 8 last year, the first indication of vedicitumab for injection was approved for marketing, and it is suitable for at least two systems Chemotherapy in patients with HER2-overexpressing locally advanced or metastatic gastric cancer, including gastroesophageal junction adenocarcinoma .
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PSA kinetics can be used to monitor nmCRPC prognosis: PSA deep remission is associated with long-term clinical benefit
Time of Update: 2022-01-26
Table 2 PSA kinetics of molecular subtypes in the apalutamide group in the SPARTAN study Correlation of PSA remission with outcomes in patients treated with apalutamide PSA reduction ≥50% and deep PSA reduction ≥90% at 6 months of treatment Or PSA ≤0.
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Heavy balls to keep or cut?
Time of Update: 2022-01-26
In the past 15 years, our center has treated 68 cases of benign testicular tumors, of which 30 cases underwent testicular-sparing surgery.
Looking back over the past 15 years, all patients considered to be benign lesions by intraoperative rapid freezing pathological examination in our center were finally diagnosed as benign testicular tumors .
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2021 Inventory of Prostate Cancer Research Progress in China
Time of Update: 2022-01-26
During the meeting, Professor Li Yonghong of Sun Yat-Sen University Cancer Center shared the articles published by Chinese researchers in prostate cancer-related fields in 2021 and recommended relevant research progress .
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Influence of prostatic prolapse into bladder (IPP) on postoperative positive margins and continence recovery
Time of Update: 2022-01-25
Introduction Robot-assisted laparoscopy and laparoscopic radical prostatectomy (LRP) are important methods for the treatment of localized and locally advanced prostate cancer . Intravesical Protrusi
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BMJ Sub-Journal: Chinese scholars found that drinking more coffee reduces the risk of prostate cancer in men
Time of Update: 2022-01-10
To study the association between coffee intake and prostate cancer risk, the research team searched a database of related cohort studies published as of September 2020 .
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Nature A new strategy for epigenetic treatment of prostate cancer based on ATPase, the SWI/SNF chromatin remodeling complex
Time of Update: 2022-01-10
Chinnaiyan’s team from the University of Michigan Center for Translational Pathology (MCTP) of the University of Michigan School of Medicine published a titled Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer in Nature Research papers .
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Professor Zhisong He: Important clinical research on urinary system tumors in 2021
Time of Update: 2022-01-10
The KEYNOTE-564 study is a randomized, double-blind, placebo-controlled phase 3 clinical trial [1], enrolled in renal clear cell carcinoma (postoperative pathology confirmed pT2 with nuclear grade 4 or sarcomatoid differentiation, pT3 or pT4 and Patients with no evidence of residual tumor [NED] after M1 were randomized 1:1 to receive pembrolizumab (200 mg, once every three weeks) or placebo, and the primary endpoint was DFS .
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New endocrine drugs: the first-line choice for CRPC treatment
Time of Update: 2022-01-10
Table 1 The efficacy and safety of enzalutamide and abiraterone for CRPC patients in the treatment of metastatic castration-resistant prostate cancer In the PREVALIL study [8], the efficacy of the Japanese/Asian subgroup is basically the same as that of the overall population .
