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Roche terminates CD40 monoclonal antibody development and advances FAP-CD40 double antibody to phase I clinical
Time of Update: 2021-07-30
A bispecific antibody RG6189 (RO7300490) that targets FAP-CD40 has entered phase I clinical trials, and Roche has eliminated non-selective CD40 agonists from the pipeline.
Among 10 hud40tg mice carrying MC38-FAP, 8 induced rapid tumor elimination in the FAP-huCD40 double antibody high-dose group (13.
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Hausen even reported 2 innovative drugs!
Time of Update: 2021-07-30
This year alone, Hansen has declared 9 new innovative drug projects, of which one has already started clinical trials .
In addition, Hansen's fastest-growing biologic drug is HS-20090, a biosimilar to Disuzumab, which started phase 1 clinical trials in September 2020 .
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Tracing to the United States: What is the resurgence of the "laboratory leak theory"?
Time of Update: 2021-07-30
In the face of the epidemic data rebounding again, the United States has continued to hype the issue of "virus traceability", pressing the World Health Organization and dumping China .
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Chinese scientists reveal the molecular mechanism of ketamine's rapid antidepressant
Time of Update: 2021-07-30
This study clearly reveals the molecular mechanism of the rapid antidepressant effect of ketamine, and provides an important theoretical basis for the design of new antidepressant drugs, especially to promote the development of ketamine-derived drugs, and brings new dawn to patients with depression .
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American scholar writes an article against politicizing the origin of the new crown virus
Time of Update: 2021-07-30
American scholar writes an article against politicizing the origin of the new crown virus American scholars write an article against the politicization of the origin of the new crow
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good news!
Time of Update: 2021-07-30
For details, see the article: Calcium Phosphate T500-Liquid API is an ideal carrier for solid preparations Pollacrine PotassiumPurolite production polacrilin potassium, and potassium, is a dry powder form weakly acidic cation exchange resin polymethacrylic acid , model Puolite ® C115KRM , CAS: 65405- 55-2 , registration number: F20210000083 .
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Local rules for the management of traditional Chinese medicine formula granules are implemented!
Time of Update: 2021-07-30
Full liberalization of access to the establishment of a unique procurement channels According to the "Announcement", Hainan Province requires in the "Implementation Rules" that enterprises that produce traditional Chinese medicine formula granules should obtain a " Drug Production License" and have the scope of production of traditional Chinese medicine decoction pieces and granules .
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Zhang Wenhong: The key to the Nanjing epidemic depends on the follow-up 1-2 weeks of monitoring
Time of Update: 2021-07-30
Zhang Wenhong, director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, said on Weibo on the 29th that no source-free community spread cases have been found in other provinces or cities that have left the tracking route of the airport, suggesting that the epidemic is still under control .
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Jiangsu Province: Announcement of Uniform Code for Medical Consumables!
Time of Update: 2021-07-30
The price was announced On October 22 of that year, the Jiangsu Provincial Public Resources Trading Center issued the "Notice on Announcement of the Uniform Coding Information for the Five Major High-Value Medical Consumables Products", which provided for the bidding (finalists) of orthopedics, general surgery, cardiothoracic surgery, and cardiopulmonary bypass in the province.
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86 new confirmed cases including 55 local cases
Time of Update: 2021-07-30
As of 24:00 on July 27, according to reports from 31 provinces (autonomous regions and municipalities) and the Xinjiang Production and Construction Corps, there are currently 862 confirmed cases (including 22 severe cases), 87,264 cured and discharged cases, and 4,636 deaths.
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After Xinlitai, the second biosimilar drug of 5 billion ``dulaglycotide'' starts clinical trial
Time of Update: 2021-07-30
On July 28th, the Insight database showed that Lepu Bio started the Phase I clinical trial of a biosimilar drug of dulaglutide for blood glucose control in patients with type 2 diabetes .
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National Medical Insurance Bureau: the cost of giving birth to three children is included in the scope of payment for maternity insurance
Time of Update: 2021-07-30
The National Medical Insurance Administration resolutely implements the decisions and deployments of the Party Central Committee and the State Council, responds to the concerns of the masses as soon as possible, and issued the "Notice on Doing a Good Job in Supporting the Three-Child Policy Maternity Insurance" (Medical Insurance Office [2021] No.
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The State Food and Drug Administration revises the instructions for vitamin B6 injections
Time of Update: 2021-07-30
The Administration decided to make unified revisions to the [Adverse Reactions] and [Contraindications] items of the Vitamin B6 injection instructions .
The Administration decided to make unified revisions to the [Adverse Reactions] and [Contraindications] items of the Vitamin B6 injection instructions .
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Coronavirus is not a virus that can be embedded in the human genome
Time of Update: 2021-07-30
Russian expert: Coronavirus is not a virus that can be embedded in the human genome Russian expert: Coronavirus is not a virus that can be embedded in the human genome Russian exper
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Notice on matters related to the registration of drug-device combination products
Time of Update: 2021-07-30
If joint review is required, the registration application materials shall be forwarded to the Medical Device Technology Review Center for simultaneous review; the drug-device combination products declared in accordance with the medical device registration shall be reviewed.
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Gao Fu and others review how Qingdao dockers were infected with the new crown
Time of Update: 2021-07-30
In fact, on October 17th last year, the official website of the China Centers for Disease Control and Prevention announced that, in the process of the traceability investigation of the new crown pneumonia epidemic in Qingdao, the China Centers for Disease Control and Prevention tested positive samples from the outer packaging of imported frozen cod carried by workers.
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The German Medical Data Project welcomes its 36th member
Time of Update: 2021-07-30
Image source: Dresden-Rosendorf Helmholtz Research CenterThe Dresden-Rosendorf Helmholtz Research Center, Germany, will be responsible for running the PIONEER project's big data platform for prostate cancer .
In addition to providing cloud infrastructure for the PIONEER big data platform, CASUS will also provide joint data analysis for all members of the project .
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3.5 billion dollars!
Time of Update: 2021-07-30
On July 27, PeptiDream and Takeda announced the expansion of Shuangfa's exclusive cooperation to develop peptide-conjugated drugs (PDCs) around the central nervous system (CNS) target .
This new collaboration expands the use of TfR1 binding peptide ligands for the treatment of neurodegenerative diseases .
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The first class 1 new drug!
Time of Update: 2021-07-30
On July 24, the CDE official website showed that Qilu Pharmaceutical submitted and accepted a listing application for a new class 1 drug "Yiluok Tablets" .
In October 2019, Qilu initiated a phase III clinical study (CTR20191231) comparing WX-0593 tablets and crizotinib in the treatment of ALK-positive non-small cell lung cancer.
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Tracing to the wrong direction: conspiracy to cover up science and politics to replace the truth
Time of Update: 2021-07-30
After the World Health Organization expert team went to China this year to jointly conduct a 28-day field study, it has reached important conclusions: the source of the new coronavirus is "very likely" from animals or nature; "very unlikely" is from laboratory leaks .
