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Inhibitory effect of tryptophan metabolism on immunity to IDH-mutant gliomas
Time of Update: 2022-11-04
Research methods First, the authors performed transcriptome sequencing (RNA-seq) on 30,000-600,000 microglia and macrophages screened from 14 HGGs. Principal component analysis showed that CD45+CD3−CD19−CD20− were isolated from 5 cases of IDH wild type (WT) and 5 cases of IDH mutant HGG based on the mutation state of IDH Hematopoietic cells were subjected to single-cell RNA-seq (scRNA-seq) and compared with 7 brain tissue controls, and 10 clusters with different transcriptions were found, corresponding to different cell types and states.
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Efficacy and safety of traditional Chinese medicine in the treatment of pancreatic cancer
Time of Update: 2022-11-04
Flowchart of the selection process:To date, there is extensive literature on evidence-based research methods in modern medicine related to the use of TCM for the prevention and treatment of PC, including some clinical observational studies and clinical trials.
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【CSCO 2022 Prospect】Progress in the global diagnosis and treatment of HPV-positive oropharyngeal cancer and current situation in China
Time of Update: 2022-11-04
com/s/EVGqivwvgoTuX_OHZlyFdA Oropharyngeal carcinoma (OPC) is one of the common head and neck malignancies, more than 90% of which are squamous cell carcinomas.
com/s/EVGqivwvgoTuX_OHZlyFdA Oropharyngeal carcinoma (OPC) is one of the common head and neck malignancies, more than 90% of which are squamous cell carcinomas.
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The latest data of personalized DNA tumor vaccines was announced, why did Nykode repeatedly reach hundreds of millions of dollars in cooperation with giants?
Time of Update: 2022-11-04
com——List of recent popular events——On November 9, nucleic acid drug process development new technologyOctober 31, 2022 / eMedClub News /-- October 26, 2022, at the Neoantigen-Based Therapies Summit in Boston Nykode Therapeutics announced the latest data from its therapeutic individualized neoantigen DNA tumor vaccine VB10.
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Weekend Topics Eat 5 foods less and learn 4 ways to stay away from the risk of inflammation to cancer
Time of Update: 2022-11-04
In 2015, an article published in the Journal of the Second Military Medical University "The relationship between diet nutrition and inflammation-cancer risk" said that the inflammatory environment in the body is an important risk factor for various cancers, and many cancers occur on the basis of chronic inflammation, such as: smoking→ tracheitis→ silicosis, and lung cancer; Gastritis→ Helicobacter pylori→ gastric cancer; chronic ulcerative colitis → colon cancer; Chronic hepatitis - liver cancer.
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HEMA Viewpoint | Professor Bai Ou: Prepare for a rainy day, SUVmax nomogram helps identify high-risk patients with early treatment failure of FL and guides individualized treatment
Time of Update: 2022-11-04
Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma and is clinically and molecularly heterogeneous. In recent years, there have been many advances in FL treatment, but about 20% o
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2022 AWE Professor Zhou Qing interpretation and Professor Wu Yilong commented on the GEMSTONE-301 study
Time of Update: 2022-11-01
At the AWE conference held online on October 22, 2022, Professor Zhou Qing of Cancer Hospital of Guangdong Provincial People's Hospital gave an in-depth interpretation of the GEMSTONE-301 study carrie
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How do breast cancer patients choose the best treatment option? Professor Fan Lei has face-to-face communication with you about "medical"
Time of Update: 2022-11-01
*For medical professionals only to read and refer to Pink Ribbon Moon DialogueProfessor Fan Lei, Department of Breast Surgery, Fudan University Cancer HospitalWith the advancement of medical technolog
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Early and rapid progression of GBM is an independent factor with poor prognosis
Time of Update: 2022-11-01
Gerben R et al. of the School of Medicine and Health of the University of Manchester in the United Kingdom reviewed the REP-related literature of GBM and conducted a meta-analysis, and concluded that
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Professor Qin Shukui's team: new treatment for liver cancer patients, median OS of 9.1 months The Lancet sub-issue
Time of Update: 2022-11-01
In a global REACH-2 study, ramoximab significantly improved overall survival (OS) in patients with advanced hepatocellular carcinoma with elevated alpha-fetoprotein (AFP) compared with placebo.
In a global REACH-2 study, ramoximab significantly improved overall survival (OS) in patients with advanced hepatocellular carcinoma with elevated alpha-fetoprotein (AFP) compared with placebo.
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ESMO pre-"research" news Locally advanced head and neck squamous cell carcinoma immune combined with chemoradiotherapy and chemotherapy still takes time
Time of Update: 2022-11-01
Long-term follow-up (4 years) confirmed that pembrolizumab monotherapy or combination chemotherapy versus first-line treatment with EXTREME regimen confers long-term survival benefits in patients with R/M HNSCC.
Long-term follow-up (4 years) confirmed that pembrolizumab monotherapy or combination chemotherapy versus first-line treatment with EXTREME regimen confers long-term survival benefits in patients with R/M HNSCC.
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ESMO field direct osimertinib "induces" stage III unresectable NSCLC with an ORR of 94%!
Time of Update: 2022-11-01
At this year's ESMO conference, a study explored the efficacy of osimertinib induction therapy in patients with EGFR-sensitive mutation stage III unresectable patients.
At this year's ESMO conference, a study explored the efficacy of osimertinib induction therapy in patients with EGFR-sensitive mutation stage III unresectable patients.
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How to achieve complete remission in patients with gastric cancer with multiple metastases?
Time of Update: 2022-11-01
, Complete remission of alpha-fetoprotein-producing gastric cancer by combined tislelizumab-apatinib treatment of a patient with proficient mismatch repair: a case report , World Journal of Surgical Oncology (2022) 20:289Click below to learn more about our clinical trial programsGastric cancer is a malignant tumor that occurs in the mucous membrane of the stomach, and cancer cells not only grow in the stomach wall, but also metastasize to other organs of the body through the blood and lymphatic system.
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Oncolytic viruses for the treatment of recurrent glioblastoma
Time of Update: 2022-11-01
Conclusion of the study The researchers observed that after a series of treatments, rGBM was infiltrated by an increasing number of effector T cells, providing a pathway for the immune "cold" GBM microenvironment to transform into a "hot" GBM microenvironment so that the immune system can more easily recognize and eliminate it.
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Professor Shu Yongqian: Sharp! The first-line treatment of bugertinib has achieved deep and sustained remission, and the long-term survival of ALK-positive advanced lung cancer can be expected
Time of Update: 2022-11-01
prefaceWith the continuous update and iteration of ALK-TKI, the survival of ALK-positive advanced non-small cell lung cancer (NSCLC) patients has been significantly improved. Among them, the new gener
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【Co-creation】2022 Fosun Pharma Oncology Summit Forum
Time of Update: 2022-11-01
Fosun Pharma sincerely invites you to visit us and gather in the cloud to create a star together!The meeting will be held at 09:00 a.
Fosun Pharma sincerely invites you to visit us and gather in the cloud to create a star together!
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ESMO Voice of China Professor He Jianxing and Professor Liang Wenhua's team: China's new lung cancer screening model can detect more stage I lung cancer patients
Time of Update: 2022-11-01
Key Results Figure 2: LDCT screening improves patient survival The questionnaire collected 109 factors, and the researchers found 8 independent risk/protective factors associated with lung cancer through multivariate model analysis.
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The peak circuit turns, the clouds are cleared| mCRC patients are failing in the first- and second-line standard treatment, and the third-line precision treatment is turning things around
Time of Update: 2022-11-01
F* is only for medical professionals to read and refer to mCRC chemotherapy is not sensitive, progressing layer by layer, and see how third-line treatment can break through the dilemmaIn recent years,
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The retrosigmoid sinus approach uses the posterior condylar catheter as an anatomical marker of craniotomy
Time of Update: 2022-11-01
Conclusion of the study Finally, the authors point out that the posterior condylar catheter vein (PCEV) is a simple, intuitive, safe, and effective intraoperative anatomical marker; Neurosurgeons can extend soft tissue separation and bony exposure into the foramen magnum, which increases visibility and operability of the CPA region.
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Effect of ELF4, an important component of the miRNA-transcription factor network, on GBM progression
Time of Update: 2022-11-01
of Texas State University in the United States used high-throughput sequencing screening, western blotting, transcriptomics analysis, lipidomics analysis and survival analysis to discover the key molecule that simultaneously regulates the receptor tyrosine kinase (RTK) signaling pathway and lipid dynamics, namely E74-like ETS transcription factor 4 (ELF4).
