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FDA plans to approve drug reports in May
Time of Update: 2021-05-23
The application is based on data from the study of LOTIS 2, which is a pivotal phase 2 clinical trial of the drug for patients with relapsed or refractory DLBCL who have previously received two or more treatments.
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Fuan Pharmaceutical's Rocuronium Bromide Injection passed the consistency evaluation of generic drugs
Time of Update: 2021-05-23
, a wholly-owned subsidiary of Fuan Pharmaceutical Group, had recently received a supplementary drug application approval notice issued by the National Medical Products Administration.
Its product rocuronium Ammonium injection passed the quality and efficacy consistency evaluation of generic drugs.
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The price difference of the same drug is nearly 2 times the pharmacy is returned
Time of Update: 2021-05-23
In the same month, the official WeChat account of Yifeng Pharmacy also issued a notice promising that if consumers are within 2 kilometers of other market institutions outside of Yifeng, they purchase drugs of the same factory and the same specifications that are lower than the retail price or membership price of the store.
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Renfu Pharmaceutical's "Midazolam Oral Solution" is about to be approved
Time of Update: 2021-05-23
Recently, the official website of NMPA showed that Yichang Renfu Pharmaceutical's registration application for category 3 generic drug "Midazolam Oral Solution" has changed to "Under Approval", and it is expected to be approved soon, becoming the first oral midazolam in China.
According to the Insight database, among the domestic midazolam oral solution preparations, Yichang Renfu Pharmaceutical Co.
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U.S. FDA approves new non-opioid dual-acting analgesic Zynrelef
Time of Update: 2021-05-23
Zynrelef is the first and only FDA-approved sustained-release dual-acting local anesthetic (DALA), which is clinically proven to provide better results within 72 hours after surgery compared with bupivacaine solution (the current standard of care) Good pain control and elimination of the need for opioids.
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New indications for Hengrui Remazolam Tosylate for Injection are reported on the market
Time of Update: 2021-05-23
On May 13th, the CDE official website showed that Hengrui had submitted a new indication of "remazolam tosylate for injection" for the marketing application and was undertaken by CDE.
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The doctor was sentenced to full responsibility for the medical malpractice caused by the broken needle left in the mother's body
Time of Update: 2021-05-23
" The "Interpretation of the Supreme People's Court on Several Issues Concerning the Applicable Law for the Trial of Medical Damage Liability Disputes (2020 Amendment)" stipulates that "patients shall comply with Article 1218 of the Civil Code.
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KIDNEY INT: Analysis of the prevalence of pain in patients with chronic kidney disease
Time of Update: 2021-05-21
041" target="_blank" rel="noopener">The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis .
041" target="_blank" rel="noopener">The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis in this message
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J Sport Rehabil: Inspiratory muscle training can effectively treat chronic low back pain
Time of Update: 2021-05-21
In summary, the results of the study show that IMT can improve respiratory function and increase core muscle activity, thereby reducing the intensity of pain in CLBP athletes.
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Neuron: Researchers use eel-like protein to control neurons to help depressed patients
Time of Update: 2021-05-21
Researchers are studying how brain neurons work to see if understanding these operations can help people with addiction, depression, and pain. In a paper published on " Neuron " on May 11, the Center
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Communications Biology: Narcotics may promote Alzheimer's disease
Time of Update: 2021-05-21
In addition, it was found that sevoflurane causes tau to leave neurons and enter microglia, where it stimulates cells to produce interleukin-6, which in turn leads to inflammation and cognitive impairment.
1038/s42003-021-02047-8The anesthetic sevoflurane induces tau trafficking from neurons to microglia Communications Biology 10.
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MIT scholars revealed: Anesthesia is not simply to make the brain into an unconscious state, but to change its rhythm!
Time of Update: 2021-05-21
The main finding of the study is that the entire cerebral cortex has a very slow rhythm feature, which is a direct measurement of how subjects are after propofol administration When entering the unconscious state provides a model of how well they are maintained in this state and how quickly they may wake up once the propofol administration is overFor a long time, through the use of scalp EEG electrodes and the use of medsci.
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Learn to explain the acid-base balance with a unified theory
Time of Update: 2021-05-10
Through the derivation of the relational formula, we get that PH (that is, [H+]) is completely affected by SID, [AT], PCO2, and everything leads to the acid-base of blood or extracellular fluid.
Recommendation: Origin of Alkali Supplement Formula Sodium bicarbonate corrects acidosis.
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What problems should be paid attention to in anesthesia for patients after radiotherapy
Time of Update: 2021-05-10
Difficult airways should be the easiest for everyone to think of complications related to anesthesia; but besides this, what issues need to be considered for radiotherapy patients before surgery?
After craniocerebral irradiation, the risk of stroke is significantly increased in patients.
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How do we choose the anesthesia method for labor analgesia and transfer to cesarean section?
Time of Update: 2021-05-10
2. Continuous epidural anesthesia [Prerequisite] The catheter is well positioned, the block plane is equal to the left and right, and the labor analgesia effect is good; [Advantages] It can be directly administered to achieve sufficient block, and it can also provide intraoperative analgesia for emergency women; [ Operational recommendations] After entering the room, check whether the epidural catheter is prolapsed and evaluate whether the labor analgesia is good; the above two are very important.
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Precautions for the use of flexible bronchoscope
Time of Update: 2021-05-10
Among them, the bronchoscope is our very important secret weapon, which is used in extremely important scenes such as difficult airways and one-lung ventilation; but if used improperly, it will damage the valuable bronchoscope.
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Count down those "very low incidence, but extremely harmful" complications in anesthesia
Time of Update: 2021-05-10
It is expected that patients with prolonged, prone position, and large blood loss are at higher risk of ischemic optic neuropathy; during spinal surgery, risk factors include men, obesity, Wilson frame, and fluid management.
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Case | Sudden "failure" of heart function during operation at the age of 16
Time of Update: 2021-05-10
Turning over to prone position after 15 minutes, the patient's vital signs were stable, blood pressure maintained at about 100/65mmHg, FloTrac cardiac function monitoring showed that SV 35ml, SVV 20, and the heart rate maintained at 80-90bpm did not change much.
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JAMA Pediatr: Epidural analgesia and risk of autism spectrum disorder in offspring
Time of Update: 2021-05-08
After adjusting for maternal sociodemographic, pre-pregnancy, pregnancy and perinatal covariates, exposure to ELA was not associated with the risk of ASD in the offspring (HR=1.
97)Studies believe that epidural analgesia does not increase the risk of autism spectrum disorder in offspring .
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Anesthesiology: Ketamine combined with magnesium preparations for treatment of refractory chronic pain will not bring additional benefits
Time of Update: 2021-05-07
Recently, a randomized, double-blind, crossover, placebo-controlled study (NCT02467517) explored the effects of ketamine in neuropathic pain that may provide pain relief and cognitive-emotional effects, as well as the effect of combined use with magnesium.
