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The study found that ICS regulation is essential for embryonic stem cell differentiation
Time of Update: 2021-02-15
Now, a Danish team of researchers has identified a damaging relationship between excess KERP levels regulated by polynucleotide-tail cytosometerial targeting (PAXT) connections and transcription controlled by polynucleotide suppression complex 2 (PRC2).
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Scientists analyze in depth the basic molecular mechanisms of self-renewal and differentiation of intestinal stem cells
Time of Update: 2021-02-11
Using professional terminology, the researchers were able to describe a detailed intestinal stem cell line tree and identify a new habitat signal, and to achieve these breakthrough results, the researchers used different reported mouse linelogies, combined with genome-wide and targeted single-cell gene expression analysis, to time-resolution genealogy markers for rare intestinal linelogies, and to analyze genealogical decision-making mechanisms for intestinal stem cells.
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for neural stem cell differentiation
Time of Update: 2020-12-30
Several studies have shown that opioids can regulate the direction of NSCs differentiation, affecting the occurrence of body-forming nerves and their ability to learn and remember, so is the effect of opioids on NSCs differentiation entirely dependent on opioid subjects?
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Science Subplot: Reveals the mechanism by which protein Phf19 controls the maintenance and differentiation of hematopoietic stem cells.
Time of Update: 2020-09-15
because of the plasticity of HSC, any changes that affect gene expression in these cells, including the on-the-look genetic regulator, can have a significant impact on blood balance.
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Glutamine rehydration metabolism and bone differentiation of interstimcharged stem cells regulated by aging inhibitor ERRalpha
Time of Update: 2020-09-08
this study reveals the new molecular path mechanism of MSC metabolic regulation and bone differentiation mTOR-ERR alpha-GLS.
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Science Subplot: Reveals the mechanism by which protein Phf19 controls the maintenance and differentiation of hematopoietic stem cells.
Time of Update: 2020-09-08
in a new study, researchers from research institutions such as the Institute of Science and Technology in Barcelona, Spain, have found that the ontogeneic genetic regulator Phf19 is crucial to HSC differentiation, and without it, blood tissue is imbalanced, equivalent to natural aging.
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The regulatory mechanism for the differentiation of human embryonic stem cells into liver cells.
Time of Update: 2020-09-05
this end, the team carried out a systematic analysis of the reverse process of somatic cell reprogramming, the directional differentiation process of erythemogenic stem cells, focusing on evaluating the role of EMT/MET process in liver differentiation.
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of sperm stem cell differentiation and subtransfact division.
Time of Update: 2020-08-25
Zhou Qi and Li Wei of the Institute of Zoology of the Chinese Academy of Sciences, in collaboration with Yang Yungui of the Beijing Genomics Research Institute of the Chinese Academy of Sciences, have revealed a new mechanism for the role of Mettl3-mediated m6A (6-methyl adenine) modification in regulating the starting process of differentiation and subtransciation of sperm stem cells.
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Superoxygen and hydrogen peroxide act as new signals to regulate the maintenance and differentiation of plant stem cells.
Time of Update: 2020-08-24
the study reveals that the signals of this new stem cell regulation may be conservative in plants and animals, and provides a theoretical basis for studying the regulatory mechanisms of the fate of ROS-mediated stem cells.
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The neural differentiation process of human embryonic stem cells hESCs is divided into five important stages, and the core determines the factor.
Time of Update: 2020-08-21
hESCs developed and differentiated into mature neurons without adding exogenous factors, which facilitated the phased study of the molecular mechanisms of stem cell fate decisions and neural processes in the human body.
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Multi-comb protein PCGF5 regulates the molecular mechanism of embryonic stem cell differentiation to neuroprecursor cells.
Time of Update: 2020-08-10
epigenetic factors that affect stem cell differentiation to neuroprecursor cells by screening, the team found that non-classical sub-PCGF5 of the PRC1 complex plays an important role in the process of stem cell neurodifferentiation.
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Human multi-energy stem cells in vitro liver differentiation key regulatory factors.
Time of Update: 2020-08-09
On May 31st, the international academic journal Stem Cell Reports published online the results of the collaborative research results of Ding Qiuyu and the Zhai Zhen Research Group of the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences, Genetic and chemical screenings cys cys cynaHDA s key regulator in hepatic of human pluripotent stem cells.
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The molecular mechanism that regulates the differentiation potential of the hematopoietic stem cell myelin is revealed.
Time of Update: 2020-08-07
On September 14th, the international academic journal Nature Communications published the latest research results of the Liu Xiaolong Research Group of the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and the Guo Fan Research Group of Huaxi Hospital of Sichuan University, "Med23 Alls akeeper gate of the myeloid of the myeloid of hematopoetic cells stem".
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Revealthe the trans-differentiation potential of Sca1 plus heart stem cells.
Time of Update: 2020-08-06
to systematically study the changes in the fate of adult Sca1 plus heart stem cells in normal physiological and heart damage conditions, the researchers established a specific marker Sca1 plus heart stem cell genealogy tracing system, anti-estrogen drug tamoxifen induction treatment 24-48 hours later, collected sample tests found Sca1-2A-CreER; R26-tdTomato mice can specifically and efficiently label Sca1 plus heart stem cells, which mainly label vascular endothelial cells and a small number of fibroblasts.
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Dr. Mar?a A. Blasco's team found that functional cells differentiated by pluripotent stem cells also carry long telomeres and are healthier.
Time of Update: 2020-08-05
Telomere-related information: Elizabeth Blackburn of the University of California, San Francisco, Carol Greider of the John Hopkin School of Medicine in Baltimore, Jack Szostak of Harvard Medical School, and the Howard Hughes Institute of Medicine were awarded the award for discovering the mechanisms of telomeres and telomerase protection chromosomes.