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Annals of Neurology: CADASIL affects multiple aspects of cerebral small blood vessel function on 7T-MRI
Time of Update: 2022-10-31
Figure 1: Cover image of the paperAutosomal dominant arterial disease of the brain with subcortical infarction and white matter encephalopathy (CADASIL) is a single-gene form of cSVD caused by mutations in the NOTCH3 gene.
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Triple reading hypertrophic duritis
Time of Update: 2022-10-31
After hormonal and anti-tuberculosis treatment, the patient underwent head MRI examination, the image and time are as follows, the most likely diagnosis is ()?
After hormonal and anti-tuberculosis treatment, the patient underwent head MRI examination, the image and time are as follows, the most likely diagnosis is ()?
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A case of vertebrobasilar fenestration malformation complicated by endovascular embolization of aneurysm complicated by spinal cord infarction
Time of Update: 2022-10-31
Fig. 8 Lateral MRI of the spine on the second day after surgery showed spinal cord ischemia with edema changes at the 2~5 level of the neck The patient, a 7-year-old woman, was transferred to Shanghai Tenth People's Hospital from other places on January 8, 2015 due to sudden head and neck pain for 2 days.
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Imaging diagnosis of cryptococcal meningitis 1-CT cases
Time of Update: 2022-10-31
【CT Image】:[Image performance]: CT non-contrast scan (A) showed a tubercle slightly dense opacity of the left temporal lobe; MRI T2WI(B) showed uneven slightly higher signal, T1WI(C) showed uneven low
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Neurology: spatial navigation in dementia-free memory clinics and its relationship to biomarkers and future dementia
Time of Update: 2022-10-31
Impaired spatial navigation is associated with transformation to dementia at 2 and 4 years and is associated with key cerebrospinal fluid and MRI biomarkers of AD and neurodegenerative diseases in patients with SCD and MCI.
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European Radiology: This imaging manifestation of EVT in ischemic stroke patients is related to the evaluation of patient prognosis!
Time of Update: 2022-10-31
The mRS score was 3 at 3 monthsThis study shows that FVH after treatment is associated with poor clinical prognosis, providing important prognostic information for patients with AIS after EVT.
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Nature | screen serotonin receptor agonists with antidepressant activity
Time of Update: 2022-10-31
Wetsel's research group collaborated in the publication of the Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity in Nature Through the screening of a virtual library of more than 75 million small molecule ligands, 17 molecules were preliminarily synthesized and tested, and the 5-HT2AR agonists (R)-69 and (R)-70 were found based on structural optimization.
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【Image knowledge】Ten typical neuroimaging signs
Time of Update: 2022-10-31
Although normal people can also have iron deposition in the brain, abnormal, age-inconsistent iron deposition is a feature of HSD, bilateral globus pallidus, substantia nigra symmetric iron-containing pigment deposition is the standard for pathological diagnosis of this disease, head MRI T2 weighting shows bilateral globus pallida symmetric high-intensity "tiger's eye sign" is the most characteristic manifestation of this disease.
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Tuberculous meningitis treatment
Time of Update: 2022-10-31
Our research shows that linezolid can effectively treat severe tuberculous meningitis Tuberculous meningitis is a disease with a very high mortality and disability rate.
Our research shows that linezolid can effectively treat severe tuberculous meningitis Tuberculous meningitis is a disease with a very high mortality and disability rate.
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Clinically rare: spontaneous spinal epidural hematoma
Time of Update: 2022-10-31
Epidural hematomas mostly occur on the dorsal side, typically manifested as sudden back tingling, with symptoms of spinal cord or nerve compression, followed by varying degrees of motor and/or sensory impairment below the painful site, and severe cases can develop into total paralysis.
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GW-ICC 2022: Chronic Insomnia, Behavioral Therapy and Medication Strategies for Adults!
Time of Update: 2022-10-31
Dr. Duan believes that the diagnosis of chronic insomnia must meet the following items A~F at the same time:There are many causes of chronic insomnia, which are more complex, and are relatively imperceptible in daily life, and there are the following treatments: cognitive behavioral therapy, drug treatment, physical therapy, and comprehensive therapy.
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Neurology: Epilepsy, vascular risk factors, and cognitive decline in older adults: a study of cardiovascular health
Time of Update: 2022-10-31
Epilepsy, Vascular Risk Factors, and Cognitive Decline in Older Adults: The Cardiovascular Health Study [published online ahead of print, 2022].
Epilepsy, Vascular Risk Factors, and Cognitive Decline in Older Adults: The Cardiovascular Health Study [published online ahead of print, 2022].
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Neurology: A meta-analysis of the incidence of amyloid-related imaging abnormalities in patients with Alzheimer's disease with anti-β-amyloid immunotherapy
Time of Update: 2022-10-31
Recently, a study published in Neurology counted the incidence of ARIA in anti-Aβ immunotherapy clinical trials, compared the incidence of different drugs and their clinical characteristics, and explored the possible predisposing factors of ARIA.
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Annals of Neurology - uses 24-hour post-treatment features to predict the prognosis after acute cerebral infarction
Time of Update: 2022-10-31
In this substudy, they found similar prediction accuracy for functional outcomes when using 24-hour NIHSS scores as a continuous or dichotomous variable in ML models.
In this substudy, they found similar prediction accuracy for functional outcomes when using 24-hour NIHSS scores as a continuous or dichotomous variable in ML models.
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Neurology: Use of hormone replacement therapy and dementia risk: a national cohort study
Time of Update: 2022-10-31
To determine the effect of hormone replacement therapy on dementia risk, a study published in Neurology conducted a retrospective cohort study using Taiwan's national claims dataset.
To determine the effect of hormone replacement therapy on dementia risk, a study published in Neurology conducted a retrospective cohort study using Taiwan's national claims dataset.
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One article to get a broken shoulder blade, dry goods!
Time of Update: 2022-10-31
Superior shoulder suspensory complex anatomy (SSSC): The shoulder suspension ligament complex consists of a ring-shaped structure and two bony protrusions, upper and lower:The annular structure consists of the coracoid process, the coracoclavicular ligament, the distal clavicle, the acromioclavicular ligament, the acromion, and the glenoid.
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Nature BE: Shengxing team at Tsinghua University and others found that thin-film silicon photodiodes can selectively activate or inhibit neural activity
Time of Update: 2022-10-31
Recently, Tsinghua University, Tsinghua University Department of Electronics, Tsinghua-IDG/McGovern Institute of Brain Science Associate Professor Sheng Xing, Chinese Academy of Sciences Shenzhen Institute of Advanced Technology, Shenzhen-Hong Kong Institute of Brain Science Innovation Institute Li Xiaojian, researcher Li Xiaojian, Beijing Institute of Technology Associate Researcher Wang Shirong, as co-corresponding authors, published in Nature Biomedical Engineering title: Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities.
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Nat Rev Drug Discov: [Review] The role and therapeutic value of astrocytes in neurological diseases
Time of Update: 2022-10-31
Figure 1: Astrocyte subsets and plasticity2Function of astrocytesAstrocytes are involved in key processes related to CNS homeostasis, including neurotransmitter circulation, ion balance, energy metabolism, regulation of synaptogenesis and synaptic transmission, and maintenance of the blood-brain barrier.
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Neurology: Racial disparities in stroke recurrence: a population-based study
Time of Update: 2022-10-31
Recurrent stroke is more common in black people, but racial disparities are much smaller and become less significant after adjusting for traditional stroke risk factors.
Recurrent stroke is more common in black people, but racial disparities are much smaller and become less significant after adjusting for traditional stroke risk factors.
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12 radiographic signs of enlarged hematoma of intracerebral hemorrhage
Time of Update: 2022-10-31
In recent years, many studies have shown that the presence of some specific imaging signs in non-contrast CT and CTA can predict the enlargement of cerebral hemorrhage hematoma.
