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Happy petting the dog! The latest research confirms that petting dogs not only strengthens the brain cognition, but also reduces stress and relieves emotions!
Time of Update: 2023-01-04
In this study, researchers studied brain activation of the prefrontal cortex in healthy subjects in a controlled trial using functional near-infrared spectroscopy (fNIRS), comparing different interaction patterns with dogs and with different interaction patterns with stuffed animals.
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Frontaging neurosci - New insights into neurodegeneration: inflammatory cytokines and the blood-brain barrier
Time of Update: 2023-01-04
In addition to major cytokines such as TNFα, IL-1β, IL-6 and their receptors, other cytokines also play an important role in neuroinflammation and neurodegeneration, which may provide some promising new targets for clinical applications in the treatment of neurological diseases and injuries.
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Optimal strategies for oxygen delivery in brain injury
Time of Update: 2023-01-04
Optimal strategies for oxygen delivery in brain injuryCritically ill Walker Translation GroupI. PrefaceOptimizing oxygen delivery is an important priority for acute brain injury (ABI), namely subarach
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Annals Neurology: Tau is a mediator of vascular risk and Aβ for cognitive decline
Time of Update: 2023-01-04
, in a group of deeply characterized CU adults who participated in the Harvard University Aging Brain Study (HABS), tested the hypothesis that increased baseline vascular risk and Aβ burden were synergistic with increased longitudinal ITC tau accumulation.
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Science sub-journal: Wu Qingfeng/Miyi team reveals developmental programming mechanisms for puberty initiation
Time of Update: 2023-01-04
On November 17, 2022, Wu Qingfeng's team from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and the miserly team from the School of Life Sciences of Tsinghua University published an online report entitled Science Advances Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset.
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CD: Jiao Jianwei's team at the Chinese Academy of Sciences found that proteins derived from humans can induce neocortical folding and improve cognitive performance in mice
Time of Update: 2023-01-04
In addition, overexpression of ARHGAP11B, TBC1D3, and TMEM14B promotes the expansion of basal progenitor cells (BPs), resulting in cortical gyration in natural brainless mice or anencephaly martens 。 However, the cellular and molecular mechanisms that control the development of oRG cells and oSVZ, and the potential of these mechanisms to drive neocortical folding, are not fully understood.
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SNX17 can increase LRP4 membrane expression, promote acetylcholine receptor aggregation, and improve EAMG
Time of Update: 2023-01-04
Keywords: myasthenia gravis; LRP4； Therapeutic targetsMyasthenia gravis ( MG) is most prominently characterized by impaired aggregation of the neuromuscular junction (NMJ), postsynaptic membrane (endp
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Neurology: Safety of SARS-CoV-2 vaccination against Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy
Time of Update: 2023-01-04
The safety of SARS-CoV-2 vaccine in patients with a history of Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and multifocal motor neuropathy (MMN) is of concern.
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Neurology: Relationship between cerebrospinal fluid GAP-43 and cognitive decline and dementia progression in amyloid-positive individuals
Time of Update: 2023-01-04
This study provides class III evidence that high baseline levels of cerebrospinal fluid GAP-43 are associated with progression in Aβ-positive individuals with more aggressive neurodegenerative processes, faster rates of cognitive decline, and an increased risk of transforming into dementia.
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Alzheimer & Dementia: Changes in peripheral leukocyte surface antigens suggest innate immunodeficiency in sporadic Alzheimer's disease
Time of Update: 2023-01-04
In summary, the study found that changes in peripheral leukocytes surface antigen in AD patients were associated with the loss of innate immunity.
the study found that changes in peripheral leukocytes surface antigen in AD patients were associated with the loss of innate immunity.
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Age & Aging: Don't underestimate weakness, it can lead to diabetes, coronary heart disease, and even stroke!
Time of Update: 2023-01-04
The results showed that higher FI predicted by posthumous prediction was significantly associated with increased risk of CAD (OR=1.
The results showed that higher FI predicted by posthumous prediction was significantly associated with increased risk of CAD (OR=1.
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Cell: Focusing on the role of SYK-dependent and non-dependent pathways in microglia in Alzheimer's disease
Time of Update: 2023-01-04
Brainnews interpreted the literature yesterday, click to view:Cell: A novel mechanism by which microglia lead to increased Aβ deposition in Alzheimer's disease, neuropathological exacerbation, and cognitive deficitsMicroglia attached to Aβ plaques acquire a transcriptional marker, the "disease-associated microglia" (DAM), which is primarily derived from the TREM2-DAP12 receptor complex that transmits intracellular signals via the protein tyrosine kinase SYK.
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JPD: plasma short-chain fatty acids can be used as biomarkers for differential diagnosis of multiple system atrophy and Parkinson's disease
Time of Update: 2023-01-04
Methods: The plasma short-chain fatty acid content of 25 patients with multisystem atrophy, 46 patients with Parkinson's disease and 46 healthy controls was detected by gas chromatography-mass spectrometry, and their demographic and clinical data were evaluated.
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Study of stable and specific neurological markers of pain resolution
Time of Update: 2023-01-01
Recently, Hu Li's research group of the Key Laboratory of Mental Health of the Chinese Academy of Sciences used EEG and functional magnetic resonance imaging technology to reveal stable and specific neural indicators of pain resolution 。 The results have been published online in Cell Reports Medicine under the title Selective and Replicable Neuroimaging-based Indicators of Pain Discriminability.
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Why does stroking relieve pain? Wang Fan's team revealed the mechanism by which touch inhibits the brain's response to painful stimuli
Time of Update: 2023-01-01
Link to the paper: style="letter-spacing: normal;font-size: 12px;color: rgb(136, 136, 136);" _mstmutation="1" _istranslated="1"> Open reprint, welcome to forward to Moments and WeChat groups Written byJia Yugeng EditorWang Duoyu TypesettingShui Chengwen It is well known that humans and animals obtain external information through a variety of sensory pathways, including touch, which is an important sensory function when living organisms are in direct contact with the external environment.
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Mol Psychiatry—Jiang Bo's research group at Nantong University reveals a new molecular mechanism by which chronic stress induces depressive-like symptoms through HPA axonal excitation
Time of Update: 2023-01-01
Written by Jiang BoResponsible editor—Wang Sizhen, Fang YiyiEditor—Sizhen WangAs we all know, depression is caused by the interaction of physiological, psychological, genetic and other factors, of whi
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Expert comment: Neuron, Shen Wei/Yang Wen/Zhang Jie co-found that TRPC4 is a key molecule in the brain to sense temperature and maintain body temperature
Time of Update: 2023-01-01
Reviews | Hu Chi An (Institute of Brain and Intelligence, Army Medical University) and Xu Tianle (Shanghai Jiao Tong University) Maintaining a constant body temperature is a necessary condition for th
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[Review]: Neuroimmune mechanisms of stress-related diseases caused by chronic social stress
Time of Update: 2023-01-01
RSD induces neuronal activation and coordinates peripheral and central immune responses that affect behavior and cognition3"Allergic" reactions to social stressHuman sensitivity to stress increases over time, so much so that a slight stressor triggers a mental disorder, a state that becomes a stress-sensitized state.
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Guarding the Brain: A Special Immune System That Protects the Brain's Gray Matter Nature's long article
Time of Update: 2023-01-01
”Since those early experiments, Schwartz's team and others have amassed a wealth of evidence that immune cells do play an important role in the brain, even without autoimmune diseases.
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The Nat Commun-Chen Zhong/Wang team revealed a new mechanism by which astrocytes are involved in seizures
Time of Update: 2023-01-01
Written by - Zhao Junli edited - Wang Sizhen, Fang Yiyi edited - Wang Sizhen epilepsy It is one of the most common neurological diseases, affecting nearly 1% of the global population, and nearly one-t
