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JAMA Neurology: New study reveals effective molecules for relieving nerve pain
Time of Update: 2020-11-02
. Richard Barohn, lead researcher and executive vice president of health affairs at the University of Missouri, said, "This study goes beyond whether drugs can reduce pain and focuses on side effects." As the first of its kind, we compared these four drugs in real life to provide evidence to doctors to support the effective management of peripheral neuropathy and to support the need for newer, more effective drugs for nerve pain.
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The study found that Peli1 regulates the phagocytosis function of small glial cells and the new mechanism of Alzheimer's pathology
Time of Update: 2020-11-02
The study revealed that E3 ubiquity connective enzyme (i.e. Peli1) directly mediates C/EBP beta ubiquity modification and induces its degradation, affecting the new mechanism of small glial cells to devour β amyloid protein (Amyloid-β, A beta), providing new molecular targets for the pathological mechanisms and clinical treatment of Alzheimer's Disease(AD).
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Biological Psython: A new mechanism for treating drug addiction
Time of Update: 2020-11-02
in the study, Yan Dong, a professor of neuroscience at the University of Pittsburgh at the University of Pittsburgh in Pennsylvania, said: "We have shown that astrological glial cells respond to the cocaine experience by promoting the formation of new synapses.
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October 2, 2020 Science Journal Essence
Time of Update: 2020-11-02
1. Science: Revealing adhesive codes to ensure that tissues and anatomical structures in embryonic development correctly form doi:10.1126/science.aba6637 In a new study, researchers from Harvard Medical School, New York University School of Medicine, and the Austrian Institute of Science and Technology have discovered a key control mechanism that cells use for self-assembly during early embryonic development.
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Target axis mutant! Lilly's $1.35 billion acquisition of Disarm Therapeutics results in a new, powerful SARM1 inhibitor program!
Time of Update: 2020-11-02
Disarm has discovered a new, powerful SARM1 inhibitor and is advancing it to preclinical research with the aim of providing breakthrough treatments for patients with peripheral neuropathy and other neurological disorders such as amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MM).
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Mol Neurobiol: Key proteins mediat the onset of Alzheimer's disease caused by excessive drinking
Time of Update: 2020-11-02
(Photo Source: www.pixabay.com) The study attempts to shed light on how excessive drinking affects the transformation of tau protein from a normal to a pathogenic building society and leads to Alzheimer's disease.
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Studies have revealed that visual timing processing sensitivity affects the feeling experience of adolescents with autism traits
Time of Update: 2020-11-02
Abnormal sensory processing capabilities are one of the outstanding clinical features of the autism spectrum disorder (ASD) group. More than 90% of ASD individuals experience abnormal sensory experie
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Neuroscientistes explain how to improve communication between different regions of the brain
Time of Update: 2020-11-02
recently, scientists from Iran, Germany and Sweden discovered a new role in two-way connections in accelerating communication between brain regions.
in essence, there are two ways to deal with the fragility and sparseness of brain connections: synchronization or oscillation.
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Neurology: Lack of interest in life may make you more likely to develop dementia
Time of Update: 2020-11-01
21, 2020 // -- In a recent study published in the international journal Newology, scientists from the Alzheimer's Research Institute and others in the United Kingdom found that individuals who lack interest in the world around them are at increased risk of developing dementia.
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Cell sub-journal interpretation! Scientists have successfully revealed the molecular mechanisms of brain memory formation!
Time of Update: 2020-11-01
In Biology's study, entitled "Ventro-dorsal Hippocampal Pathway Gates Novelty-Induced Contextual Memory Formation", scientists from the Austrian Academy of Science and Technology and others used their research to uncover a new cornerstone of memory formation, in which researchers studied special signaling pathways in the hippocampus regions of the brain and revealed how the pathways control new memories formed when the body experiences a new environment.
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Chinese epilepsy patients gospel! A new generation of anti-epileptic drug ® (Fycompa, ®) 2 supplementary applications were accepted!
Time of Update: 2020-11-01
In addition, Fycompa has been approved by more than 65 countries worldwide, including the United States, Japan and other European and Asian countries, as an ancillary therapy for the treatment of primary full-range PGTC seizures in patients with epilepsy aged 12 years and older.
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New medicine for rare diseases! Libmeldy, an innard CD34 plus cell gene therapy, is recommended by THECHMP: One treatment solves the underlying cause!
Time of Update: 2020-11-01
recently, the company announced that the European Medicines Agency (EMA) Committee on Human Pharmaceutical Products (CHMP) has issued an active review recommending full or standard approval for Libmeldy (frozen auto-CD34 plus cells encoding alfalgenate-A), a gene therapy based on auto-CD34 plus cells for the treatment of isotide cerebral leukotrophy (MLD).
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The study revealed feeling patterns in healthy adolescents and early-onc developing schizophrenia
Time of Update: 2020-11-01
The Chen Chu overseas Chinese Research Group of the Mental Health Key Laboratory of the Institute of Psychology of the Chinese Academy of Sciences explored the sensitivity of the sensations of healthy adolescents (98) and patients with early onset schizophrenia (29) and examined their relationship with clinical symptoms and subclinical traits.
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The essence of the October 9, 2020 issue of Science
Time of Update: 2020-11-01
A new class of inhibitors can effectively prevent neurodegeneration and is expected to treat a range of neurodegenerative diseases doi:10.1126/science.aay3302; In a new study, researchers from the University of Heidelberg in Germany have discovered how a special subject located at a neural connection, or synapse, usually activates a protective genetic procedure, causes nerve cell death when located outside the synapse.
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Rare new drug for children with epilepsy! Fintepla (fenfluoramine oral solution) is recommended by the EU CHMP for the treatment of Dravet syndrome!
Time of Update: 2020-11-01
recently, the company announced that the European Medicines Agency (EMA) Human Pharmaceutical Products Committee (CHMP) has issued an active review recommending approval of Fenfluramine oral solution as an additional (add-on) therapy for other anti-epileptic drugs for patients ≥2 years of age with Dravet syndrome.
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October 16, 2020 Science Journal Essence
Time of Update: 2020-11-01
study was published in the October 16, 2020 issue of the Journal of Science under the title "Apical stress fibers enable a scaling between cell mechanical response and area in the epielial tissue." the researchers studied the skin cells in the back or lower back of the fruit fly.
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PNAS: Break the traditional cognition! Lipids or play a key role in the on-the-go development of Parkinson's disease!
Time of Update: 2020-10-31
24, 2020 // -- In a recent study published in the international journal Proceedings of the National Academy of Sciences, scientists from institutions such as the McLean Hospital found that lipid changes in a class of key brain cells may play a key role in inflammation and Parkinson's disease, and the results are expected to help develop new treatments for Parkinson's disease.
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Neuron interpretation! Uncover the key role dopamine and serotonin play in regulating human perception and decision-making skills!
Time of Update: 2020-10-31
October 23, 2020 // -- A recent article published in the international magazine Neuron entitled "Sub-second Dopamine and Serotonin Signaling in Human Striatum when Perceptual Decision-Making" In the study, scientists from institutions such as University College London documented real-time changes in dopamine-good serotonin levels in the human brain involved in perception and decision-making, which are essential for the body's motor disorders and mental disorders, including substance abuse and depression.
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Studies have revealed a link between DNA dna dna and Alzheimer's disease
Time of Update: 2020-10-31
Alzheimer's Disease (AD) is a multi-factor disease closely related to aging. main neuropathological features of AD are β-amyloid protein deposition to form plaques and micro-tube protein tau excessiv
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Low-profile mascust men are more likely to be unfaithful and invest less in relationships!
Time of Update: 2020-10-31
In the study, the researchers analyzed three sound parameters of the participants, namely the basic frequency of sound (F0), the standard deviation within F0's discourse (F0-sd), and the position of the resonance peak (Pf), and based on the participants' self-reported questionnaires, they explored the association between sound parameters and an individual's infidelity and relationship commitment.
