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Research reveals the neural mechanisms of animal social desire
Time of Update: 2020-11-10
On October 22, Zhu Yan of the Institute of Biophysics of the Chinese Academy of Sciences published a research paper entitled Social attraction in Drosophila issioned by the mushroom body and serotonergic system in Nature Communications, which examines fruit flies as models to create new paradigms of social affinity behavior to quantify the intrinsic drivers of animal active social interaction and to reveal the neural mechanisms of animal social desire.
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A new intelligent drug system for the treatment of neurological diseases
Time of Update: 2020-11-09
In a new study published in Advanced Materials, a team led by Rutgers University in the United States has developed an intelligent drug delivery system that can reduce inflammation of damaged nerve tissue and help treat spinal cord injuries and other diseases that cause neurological disorders.
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How have scientists used "mini" organizations in recent years to help improve human health research?
Time of Update: 2020-11-09
In recent years, as scientists have developed a variety of "mini" organizations to help their research progress and improve human health, in this article, the editor-in-chief on the relevant importan
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The study found that people with schizophrenia felt impaired in unification with a decrease in the activation of their small brain
Time of Update: 2020-11-09
study found that patients with schizophrenia showed significantly lower levels of brain activation in the healthy control group when performing sensory unification tasks, which were associated with functional connections within the microcephaly, while decreased microcephaly activation was also found in siblings who were not sick.
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Highlights to be read in the October 2020 issue of Science
Time of Update: 2020-11-08
In a new study, researchers from the Barcelona Institute of Technology, the University of Pompe fabra and the University of Applied Sciences in Upper Austria revealed that squeezing cells to the point where their nuclei begin to stretch triggers the activation of motor proteins, which in turn alters the cell's cytostebrae, allowing it to escape crowded environments.
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October 23, 2020 Science Journal Essence
Time of Update: 2020-11-08
Two Science papers reveal that some cases of severe COVID-19 are related to genetic mutations or attacks on autoantibodies in the human body doi:10.1126/science.abd4570; doi:10.1126/science.abd4585; doi:10.1126/science.abe7591 New coronavirus SARS-CoV-2 causes coronavirus disease (COVID-19) in 2019 and is now raging around the world.
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Highlights to be read in the October 2020 issue of Cell
Time of Update: 2020-11-08
study was recently published in the Journal of Cell under the title "Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infect".
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JNNP: Cerebrospinal fluid phospholipids: a new demyelination biomarker used in the diagnosis and treatment of CIDP and GBS
Time of Update: 2020-11-07
authors verify that phospholipids (SM) in a patient's cerebrospinal fluid are a reliable biomarker of chronic inflammatory demyelinative polyneurogen neuropathy (CIDP) and Green-Barre syndrome (GBS).
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Nat Neurosci exophages may prolong the survival of ALS patients
Time of Update: 2020-11-07
In the ALS mouse model, cell replacement was used to target gene regulation of reactive oxygen species pathways in exos peritonal bone marrow cells in ALS mice, reducing the activation of exosymperic macrophages and small glial cells, finding delayed symptoms and improving survival.
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Mol Psych: Study reveals different mechanisms of action between cocaine and sugar
Time of Update: 2020-11-07
(Photo: www.pixabay.com) Ana Clara Bobadilla, assistant professor of medical education programs at the University of Washington School of Pharmacy and WWAMI (Washington, Wyoming, Alaska, Montana, and Idaho), said: "We found that most of the areas stimulated by sucrose and cocaine do not overlap in the volt core.
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Autophagy: The antidepressant Shellyn targets mitochondrial VDAC1 proteins to regulate autophagy
Time of Update: 2020-11-07
further, Sert inhibits tau disease by inducing autophagy by promoting autophagy degradation of the MAPT (micro-tube-related protein tau) protein.
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J neurosci: Study reveals the underlying mechanisms of cocaine addiction
Time of Update: 2020-11-07
November 1, 2020 /--- -- In a recent issue of Journal of Neuroscience, researchers at South Carolina Medical University and the National Institutes of Health described how drug use alerts change specific brain cells responsible for motivation, increasing the desire to seek drugs.
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Aging Cell: New ways to regulate the production and degradation of A-beta have been discovered
Time of Update: 2020-11-07
Recently, researchers at Aging Cell studied how insulin degradation enzymes (IDEs), one of the main A-beta degradation enzymes, regulate molecular mechanisms, and how amyloid prelosor protein (APP) processing and A-beta degradation are linked in a regulatory cycle to achieve this balance.
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Alzheimer's and Dementia: New antibodies target tau protein oligomers and promote the removal of lysosomes of tau proteins in cells
Time of Update: 2020-11-07
Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and in-cell tau tangles consisting of amyloid protein β (A beta).
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SCIENCE: What are the factors that make up the size of the human brain?
Time of Update: 2020-11-07
using the organization's screening method, researchers have increased screening vectors and tested 173 candidate genes for cerebral atrophy, revealing that 25 genes were involved in known and unsealed pathfration of small brain atrophy.
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Nat Immunol: Scientists have discovered a new type of cell that can promote the regeneration of the central nervous system!
Time of Update: 2020-11-06
https://doi.org/10.1038/s41590-020-00813-0 The study's lead author, Dr. Andrew Sass of the Institute of Neuroscience at Ohio State University, said, "Our findings could eventually lead to the development of new immunotherapy that reverses central nerve damage and restores the nerve function lost in patients with various diseases." strategy to promote neuropulation and regeneration is to regulate local immune responses to damage to the central nervous system.
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JNNP: Study of sleep-wake disorder in patients with hereditary and non-hereditary amyotrophic lateral sclerosis
Time of Update: 2020-11-06
Objective: To study the occurrence and clinical characteristics of sleep disorders in patients with amyotrophic lateral sclerosis (ALS), and to compare the sleep disorders of patients with alS with mutations.
that in the current study, patients with hereditary ALS were more likely to develop sleep-wake disorder than those without hereditary amyotrophic lateral sclerosis.
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JNNP: Late-oncological vitamin B2 transport protein deficiency is associated with various causes of motor neuropathy
Time of Update: 2020-11-06
studies have shown that RTDs have been linked in recent years to brown Vialetto Van Laere (BVVL) syndrome, a genetic disorder associated with motor neuropathy (MN) and deafness.
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Nat Immunol: Scientists have discovered a new type of cell that can promote the regeneration of the central nervous system!
Time of Update: 2020-11-06
Benjamin Segal, co-author of the report and a professor at Ohio State University's Institute of Neuroscience, said: "This growth factor secreted by the immunocellular subteum enhances the survival of post-traumatic nerve cells in the central nervous system and stimulates the regeneration of broken nerve fibers in the central nervous system, which is truly unprecedented.
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Save migraines! The path to discovery of CGRP inhibitors
Time of Update: 2020-11-06
, CGRP targeted drugs used to treat acute migraine attacks appear to cause only minor side effects such as constipation in a small number of people.
, for example, CGRP antibodies are used to prevent migraine attacks, gepant is used to treat acute seizures, is there a drug that can balance two effects?
