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Cell interpretation! Scientists have developed new tools to observe and control nerve activity in the brain!
Time of Update: 2020-12-22
December 21, 2020 // -- In a recent study published in the international journal Cell entitled "A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion Aversion", scientists from
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J Neurol Neurosur Ps: Spontaneous cerebral hemorrhage survivors have long-term decreased function
Time of Update: 2020-12-22
In a recent study published in Journal Of Neurology Neurosurgery And psychic, an authoritative journal in the field of neurology, the study aims to identify baseline characteristics of patients who survive within six months of spontaneous cerebral hemorrhage (ICH) and new clinical events associated with decreased function.
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JNNP: Plasma glial fibrous acid protein and neural filament light chain are the indicators to measure the severity of the disease in patients with primary aphdorexia
Time of Update: 2020-12-22
Semantic variant primary aphdrenapath (svPPA) is a neurodegenerative disease characterized by loss of conceptual knowledge, usually characterized by difficulty finding words, impaired understanding of individual words, and atrophy of the temporal lobe.
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J Infect Chemother: Epidemiological and risk factors for CRE-induced neurosurgery bacterial meningitis/encephalitis
Time of Update: 2020-12-22
, a single-variable analysis showed that the risk factors for CRE meningitis were ventilators, bacteremia, hospitalization in the intensive care unit (ICU), hospital-based pneumonia, and death from infection.
multivariative analysis shows that hospital-based pneumonia and infection-caused deaths are independent risk factors for CRE meningitis.
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Lancet Neurology: Treatment of Parkinson's disease (INTREPID) with multiple independent constant flow control devices to stimulate deep brain tissue in the hyalthesis of the hyalthesis: a multi-center, double-blind, randomized controlled study
Time of Update: 2020-12-22
The main results of this study were differences in the average daily waking time of patients in the active and control groups over the three months from baseline examination to random grouping, with well-controlled symptoms, no significant movement disorders, and no increase in anti-Parkinson's drugs.
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Lancet Neurology: Comparison of unrecrupted cerebrovascular malformation (ARUBA) drug interventional therapy with simple drug therapy: final follow-up in a multi-center, non-blind, randomized controlled trial
Time of Update: 2020-12-22
summary, after an average of 50 months of follow-up, in the ARUBA trial, individual drug therapy was still better than drug-combined interventional therapy for the prevention of death or symptomatic stroke in patients with unresolbed cerebral vein malformations.
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JNNP: Rethinking of the functional evaluation scale for amyotrophic lateral sclerosis in ALS clinical trials
Time of Update: 2020-12-22
in the absence of objective biomarkers, questionnaires such as the ALSFRS Functional Assessment Scale (ALSFRS) were used in clinical trials to assess the effectiveness of treatment.
sensitivity of ALSFRS and ALSFRS-R to detect therapeutic effects with the signal-to-noise ratio and the required sample size.
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JNNP: A fully automated cognitive screening tool based on speech and language assessment
Time of Update: 2020-12-22
In the bidirectional distinction between patients who may have neurodegenerative and non-aggressive diseases, the Cognospiak system was 87 percent accurate in identifying MCI or AD, while the participants were correctly assigned to HC or FD with 77 percent accuracy.
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Heart: Relationship between the deactivation of oral anticoagulants and the risk of ischemic stroke in patients with atrial fibrillation
Time of Update: 2020-12-22
A recent study published in Heart, an authoritative journal in the field of cardiology, aims to assess the link between the deactivation of oral anticoagulants (OAC) and the risk of ischemic stroke (IS) in patients with atrial fibrillation (AF).
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Nat Commun: Essential omega-3 fatty acids regulate the developing brain
Time of Update: 2020-12-22
, however, it is not clear how the n-3 PUFAs lack mechanisms that affect the development of the central nervous system.
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Ann Neurol: Relationship between the time of venous thrombosis treatment and thrombosis and outcomes in patients with acute ischemic stroke
Time of Update: 2020-12-22
the extension of EVT to IVT time at the beginning of the patient's 90-day poor functional outcome (mRS is 0-2, and the correction ratio for each additional 30 minutes is 0.91 (95 percent) than the ratio of .aOR.
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J ALZHEIMERS DIS: Cheese and wine may prevent cognitive decline
Time of Update: 2020-12-22
, of course, it is well known that excessive consumption of salt affects physical health, and people at high risk of Alzheimer's disease should pay more attention to their intake to avoid cognitive problems over time.
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JNNP: Risk of health defect accumulation, lipoprotein E genotype and late-onset cognitive impairment and dementia
Time of Update: 2020-12-22
study whether the accumulation of APOE genotypes and health defects is independent of mild cognitive impairment (MCI) and the risk of dementia.
using a multi-state transition model, we assessed the extent to which increased weakness affects the probability of transition between non-cognitive impairment (NCI), MCI, and dementia.
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JNNP: Anti-MOG antibody-related diseases - differences in clinical characteristics and prognostics in Japan and Germany
Time of Update: 2020-12-22
study the regional and ethnic differences in the clinical characteristics of MOG-IgG-related diseases in patients in East Asia (Japan) and Caucasus (Germany).
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Neurology: Global prevalence and prevalence of optic neurospinalitis
Time of Update: 2020-12-22
researchers identified 33 related articles, which showed that in the African-Caribbean region, the incidence and prevalence of NMOSD was highest in the region(0.73/100,000 people per year (95% CI:0.45-1.01) and 10/100,000 (95% CI:6.8-13.2).
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JNNP: Suggestive of functional neurological disorders: a meta-analysis
Time of Update: 2020-12-22
the authors conducted a randomized meta-analysis of all suggestive control studies of FND subsypes, including somatosal disorder/Briquet syndrome.
of the 26,643 search results, 19 articles provided 11 standardized suggestive data sets (FND:n=316; contrast: n=360) and 11 symptom suggestive data sets (FND:n=1285; contrast:n=1409) were included in the random effect meta-analysis.
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Nat Neurosci: Based on single-cell RNA sequencing, it depicts the diversity of intestinal neuron species
Time of Update: 2020-12-22
To understand the general and specific differentiation processes of ENC1-12 formation, the researchers analyzed the entire ENS sequence isolated from the small intestine of the Wnt1Cre-R26 tumor at gynaebage E15.5 and E18.5, when most intermuscular neuron types had been generated.
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FDA approves PHASE III clinical trial of AMZ002 for the treatment of epilepsy in infants
Time of Update: 2020-12-22
Infant epilepsy can lead to delayed overall neurodevelopment, severe intellectual disability, limited treatment options and poor prognosis.
pharmaceutical company AMZELL recently announced that it has concluded discussions with the FDA and will conduct a Phase III clinical trial of AMZ002 to treat epilepsy in infants.
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Middle-life thopress pressure control helps reduce the risk of future brain injury
Time of Update: 2020-12-22
Karolina Wartolowska, a clinical researcher at the Stroke and Dementia Prevention Centre at the University of Oxford in the UK, carried out the study to look for "white high-intensity" (WMH) damage in the brain.
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Progress was made in the study of different functions in the selection of different sub-regions of the frontal frontal leaf
Time of Update: 2020-12-21
study found that in the process of value selection, the pre-cortical cortical layer encodes only the value information carried by a single evidence at the visual feature level, and the outer frontal frontal leaf region encodes not only the accumulation of evidence at the motion level, but also the conversion of individual evidence from visual features to motion-related information.