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Professor Wang Jian'an: From the stroke prevention of atrial fibrillation patients, look at the future development of LAAC
Time of Update: 2021-01-18
In China's population aging process is accelerating today, the rising incidence of cardiovascular diseases to the community and families have brought a heavy burden, atrial fibrillation as the most common arrhyth arrhythmic in the clinic, greatly increased the risk of stroke patients, and left ear blocking (LAAC) as an effective way to prevent and control atrial fibrillation, for the majority of atrial fibrillation patients provide a new choice.
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Stroke: The prevalence of sleep disorders after stroke or transient ischemic episodes of the brain
Time of Update: 2021-01-18
Recently, a study published in the leading journal in the field of cardiovascular disease, researchers aim to identify the prevalence of acute, subacute and chronic sleep apnea, insomnia, periodic leg movements, and restless leg syndrome after stroke or TIA, and to assess the role of characteristics (e.g. age) and methodological characteristics (e.g., study quality) in regulating prevalence.
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BRAIN: Protein promotes Alzheimer's disease and age-related primary tauopathy brain atrophy
Time of Update: 2021-01-17
results show that TDP-43 and tau contribute differently to the acceleration and deceleration of the brain atrophy rate of Alzheimer's disease and primary age-related tauopathy over time.
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The Chen Gong team at Jinan University used neurogenetic gene therapy to bring new hope to patients with spinal cord injuries
Time of Update: 2021-01-17
Traditional spinal cord injury treatment strategies focus primarily on promoting axon regeneration of residual neurons or transplanting external stem cells to intervene, while Professor Chen gong and his team use endogenetic assosteroid glial cells in the injured spinal cord to convert them directly into functional new neurons.
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Neurology: Tau lesions in the forehead cortical cortical layer are highly correlevant to behavioral/execution disorder-type AD
Time of Update: 2021-01-17
Subsequent larger studies did not find substantial preleteual atrophy, resulting in "behavioral/execution disorder AD" exceeding "preletain variation AD", however, these larger studies did not assess the distribution of A-beta or Tau proteins, which may be associated with clinical manifestations and can predict local neurodegenerative lesions.
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BRAIN: Is white matter integrity associated with cognition and disease severity in patients with Fabry disease?
Time of Update: 2021-01-17
here, the researchers assessed patterns of DTI abnormalities in Fabri's disease and their correlation with cognitive impairment, mood, anxiety, severity of the disease and plasma-soluble Gb3 levels in 31 genetically proven Fabri disease and 19 age-matched healthy control subjects.
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BRAIN: REM sleep behavior disorder and subsequent Parkinson's esomor
Time of Update: 2021-01-17
Because current RBD animal models are not based on α-type synhapus nucleoprotein disease, they do not represent the pathological substrates of idiopathic RBD and cannot be modeled as esoteric transformations of Parkinson's disease.
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BRAIN: 18F-flortaucipir PET compared to autopsies in Alzheimer's disease and other neurodegenerative diseases
Time of Update: 2021-01-17
calculates the average of SURVs for sexual nuclear paralysis, cortical substrate degeneration, and the entanglement of neurogenic fibers of interest in the Braak period region, and compares these values with SUVR (used as a tau negative standard) derived from young non-autopsy, cognitive normal control.
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BRAIN: GABA and glutamate deficiency in frontal temporal lobe degeneration are associated with de-inhibition
Time of Update: 2021-01-17
participants with frontal temporal lobe dementia and aggressive nuclear paralysis had weak reactive inhibition and longer signal response times than the control group.
gabA and glutamate concentrations in the lower forehead are inversely proportional to the stop signal reaction time, indicating that impulsivity is proportional to the loss of each neurotransmitter.
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STROKE: Fatty liver may increase the risk of stroke
Time of Update: 2021-01-17
, "fatty liver" may seem flat, but it increases the risk of a variety of diseases, including stroke, in the future.
Severity of Nonalcoholic Fatty Liver Disease and Risk of Future Ischemic Stroke Events.
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JAMA Psychic: Relationship between family health during pregnancy and neurodevelopment of the brain in children
Time of Update: 2021-01-17
addition, after adjusting for the mixing factors, the sea mass partially mediated the association between poor family function reported by prenatal mothers and pre-adolescent problem behavior (B s 0.08; 95% CI, 0.03-0.13).
, the study showed that prenatal mothers reported poor family function associated with smaller sea mass in pre-adolescent children.
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Neurology: Slow-wave sleep decreases or accelerates brain aging
Time of Update: 2021-01-17
breakthrough study, sleep, especially slow-wave activity, was associated with an increase in the rate of glycobolic removal of amyloid protein (A-β) in the brain.
Slow-wave Sleep and MRI Markers of Brain Aging in a Community-based Sample.
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JAMA Sub-Journal: Assessment of Suicide Deaths among Veterans' Minorities
Time of Update: 2021-01-17
study found that compared to the U.S. population in general and veterans in general, the veterans SM group had a rough and age-adjusted mortality rate from all deaths and suicides.
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Alzheimer's and Dementia: LDL cholesterol and urinary glycoside levels predict clinical progress of AD
Time of Update: 2021-01-17
A recent study suggests a nutritional risk index, including levels of omega-3 fatty acids, vitamin D, and homocysteine, that may help identify older people with a reduced risk of cognitive decline who have not yet developed a phenolype of dementia.
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Stroke: A study of 20,000 people found that stroke patients with both diabetes and depression were more likely to have dementia and lose their ability to become independent
Time of Update: 2021-01-17
, diabetes and depression were significantly associated with long-term care hospitalization, dementia events, stroke/TIA re-hospitalization, and all-cause mortality, respectively.
importance of this study is that when diabetes and depression are present at the same time, the risk of long-term care after dementia and stroke is higher among women.
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BRAIN: The network controllability and regional gene expression differences behind Parkinson's disease hallucinations
Time of Update: 2021-01-17
to solve this problem, this study looked at changes in structural connectivity associated with Parkinson's disease accompanied by visual hallucinations, as well as tissue and gene expression characteristics in the affected areas of the network.
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Eur Radiol: With regard to multi-system atrophy, is it too late to make a diagnosis by "cross-bread"?!
Time of Update: 2021-01-17
The results of the correlation analysis of MCP sT1w/T2w ratio with ICARS score show that the sT1w/T2w ratio can identify MSA-C-related changes in MCP at an early stage and may serve as a sensitive biomarker for the detection and diagnosis of MSA-C.
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The Lancet sub-| A prospective study of the British Biological Sample Bank: The relationship between physical weakness and the onset of dementia
Time of Update: 2021-01-17
of the five components used to define weakness, weight loss, fatigue, low grip and slow gait increased the risk of dementia by 31%, 48%, 38% and 55%, respectively.
shows that both pre-weakness and weakness increase the risk of dementia.
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Neurology: Angiotensin II stimulates antihypertensive drugs, or helps prevent dementia
Time of Update: 2021-01-17
, studies of lower blood pressure in older adults have shown that reducing the risk of Alzheimer's disease has many effects.
other antihypertensive drugs, the subcatfacies most associated with reducing the risk of dementia are angiotensin blockers, certain calcium channel blockers, and diuretics.
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BRAIN: Abnormal symposydroid dopamine in schizophrenia is structurally associated with cortical-pausc brain insemination
Time of Update: 2021-01-17
in a system centered on a significant network, the patient's synthesized dopamine synthesis was reduced, which was positively associated with a significant network-central-cerial iFC decrease.
In a system centered on an auditory-sensory motor network, the patient's sensory motor synthesized dopamine synthesis was positively associated with an increase in the auditory-sensory motor network-abdominal cerum iFC.
