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Nat Aging: Alzheimer's disease vaccine is here!
Time of Update: 2021-06-21
ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease .
Nature ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease Aging (2 021) Leave a message here
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JAMA Netw Open: Long-term consumption of gluten will not affect cognitive function
Time of Update: 2021-06-21
Recently, a study published in the journal JAMA Netw Open found that in the absence of celiac disease, long-term or short-term intake of gluten has no correlation with cognitive function .
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Radiology: Local network efficiency mediates the adverse effect of white matter hyperintensity lesion volume on cognitive function
Time of Update: 2021-06-21
A, MRI scan showed that the white matter hyperintensity (WMH) volume of specific fiber tracts was significantly correlated with the information processing speed score (P, 0.
A, MRI scan showed that the white matter hyperintensity (WMH) volume of specific fiber tracts was significantly correlated with the information processing speed score (P, 0.
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"Unilateral deafness" has become a hot spot in Beijing International Audiology Conference. Sound medical treatment brings global...
Time of Update: 2021-06-20
People with unilateral deafness and hearing impaired in the noisy environment of social and work scenes have a significant decline in speech recognition ability, which seriously affects the ability of both ears to listen in the brain The integration effect, loss of sound source localization ability, will cause certain safety hazards, work and life energy will also be scattered .
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FDA approves new technology to relieve pain from osteoarthritis without medicine or surgery
Time of Update: 2021-06-20
It introduces a non-opioid non-invasive treatment option for patients seeking to relieve knee osteoarthritis pain, while being able to remotely provide real-time progress data to doctors .
[1] CyMedica Orthopedics Announces FDA Clearance for IntelliHab™, a Novel Drug-free, Non-invasive Modality for Treatment of Knee Osteoarthritis Pain.
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Alzheimer's is saved!
Time of Update: 2021-06-20
At the same time, the approval of this new therapy also brings new hope for the treatment of targeted amyloid protein, which is expected to benefit more than 100 million Alzheimer's patients worldwide and reduce the burden .
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Deciphering the detailed structure of the disease-causing protein of Parkinson's disease. Researchers open up a new way for the development of new drugs...
Time of Update: 2021-06-19
This result provides structural insights for the development of new therapies to treat Parkinson's disease, and opens up a research approach that specifically targets abnormal LRRK2 proteins .
Researchers can further design drugs to inactivate this mutant by analyzing the structure of this mutant, providing an opportunity to treat Parkinson's disease .
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"Unlimited cancer types" continued remission for more than 4 years!
Time of Update: 2021-06-19
Larotrectinib has high activity, rapid and durable remission, prolonged survival benefit and good long-term safety characteristics in advanced lung cancer patients carrying NTRK gene fusion .
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How does Germany achieve the efficiency and completeness of approvals?
Time of Update: 2021-06-19
Through the review of the relevant product quality statements (such as data protection, interactivity and user experience), and the evaluation of the medically beneficial evidence of the corresponding application software application (the application's impact on the possibility of improving the user's health or dealing with their diseases), BfArM will determine whether its DiGA application is approved .
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One-hour treatment can improve depression symptoms and two weeks "Science" reveals new uses of "laughing gas"
Time of Update: 2021-06-19
In this study, scientists conducted a phase 2 clinical trial, using different concentrations of nitrous oxide to treat 20 patients with severely drug-resistant major depression.
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China Session (4): Intestinal-mediated inflammatory response caused by sleep deprivation from the team of Academician Han Ying/Lu Lin of Peking University
Time of Update: 2021-06-18
After they transplanted adult intestinal flora after sleep deprivation into mice, the serum levels of TNF-α, IL-1β, IL-6 and other pro-inflammatory factors in these mice increased, and the integrity of intestinal epithelial cells was also Destruction appears, showing cognitive dysfunction .
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Cell Metab new brain glycogen function
Time of Update: 2021-06-18
The researchers further revealed that glycogen-derived glucosamine is an important precursor metabolite for the production of GlcNAc and N-sugar through in vitro knockdown experiments combined with metabolic analysis and isotope tracing technology (Figure 2) .
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Current Biology Sheng Zuhang's team reveals a new mechanism for neuronal axon damage response signals to regulate energy metabolism and promote survival and regeneration after injury
Time of Update: 2021-06-18
On June 3, 2021, the National Institute of Health (NIH) Sheng Zuhang team published a research paper entitled Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia in Current Biology .
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insomnia?
Time of Update: 2021-06-18
This new study found that the melatonin circadian time (DLMO) of myopic people is delayed by more than an hour compared to those with normal vision .
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Intestinal neurons control your diet and blood sugar in this way, Max Planck in Germany "fancy" anatomy of the intestinal-brain axis
Time of Update: 2021-06-18
The signal is transmitted to the parabrachial nucleus neurons that inhibit eating, and GRP65 vagus nerve afferents that innervate the intestinal nerves stimulate the peripheral liver to synthesize glucose .
002, the pictures in the text are all from the reference original download link: https://pan.
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There is a picture and a video: The nystagmus mechanism (V2.0) of the posterior semicircular canal BPPV "Halo" strategizes
Time of Update: 2021-06-18
Figure 12 Schematic diagram of the nystagmus induced by PC-BPPV on the right side (excited pathway) Figure 13 Schematic diagram of the nystagmus induced by PC-BPPV on the right side (inhibitory pathway) Dix-Hallpike of atypical PC-BPPV During the test, the otoliths in the posterior semicircular canal may be located in different positions of the lumen, such as the back arm, forearm, side of the crest cap tube, side of the crest cap capsule, near the total foot, etc.
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[New research] Discovery of the chronic pain treatment process!
Time of Update: 2021-06-18
With the discovery of this CRISPR therapy that inhibits pain genes, humans have one more method for the treatment of pain, and compared with commonly used drugs for pain relief, it has no side effects.
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How to apply near-infrared functional brain imaging in clinical practice?
Time of Update: 2021-06-18
4. When conducting brain function examinations based on fNIRS technology, it should be noted that the signal quality of the frontal lobe without hair coverage and other brain areas covered by hair (such as parietal lobe, temporal lobe, occipital lobe) , To ensure the validity of the examination results.
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Can medication reduce the risk of stroke recurrence in patients with the carotid artery network?
Time of Update: 2021-06-18
A systematic review in 2018 reported that the recurrence rate of ischemic stroke in CW patients receiving medication was 56% (median time to recurrence of stroke is 12 months, range 0-97 months), but these data All come from case reports and uncontrolled, retrospective, single-center studies .
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Cell Journal: This miRNA can reverse Alzheimer's memory loss
Time of Update: 2021-06-18
The study confirmed that adult hippocampal neurogenesis (AHN) is directly affected by the pathology of Alzheimer's disease (AD) and revealed the potential therapeutic potential of increasing miR-132 levels in neurodegenerative diseases .
