-
JAMA Neurology-After 20 years of follow-up, it was found that the overall disability rate of children with multiple sclerosis gradually decreased
Time of Update: 2021-07-27
diagnosisSo far, in adults with multiple sclerosis, the risk of reaching persistent disability has gradually decreased over time; however, this finding has not been confirmed in the POMS population, and their management is subject to DMTs approved before the age of 18.
-
JAMA Sub-Journal: The systolic blood pressure at the onset of new TIA and minor stroke determines the 90-day DAPT treatment benefit
Time of Update: 2021-07-27
A post-event analysis of CHANCE reported that DAPT was associated with a lower risk of stroke recurrence in patients with baseline systolic blood pressure (SBP) ≥140mmHg , but there was no formal examination of the interaction between blood pressure and treatment groups, and it was limited to Asia Research participants .
-
JAMA Neurology-meta-analysis: great vessel stroke, timely thrombus removal, time is life
Time of Update: 2021-07-27
The important significance of this meta-analysis is the discovery that delays in care are related to the loss of healthy life years for patients with acute ischemic stroke treated with EVT, especially in the time period after arrival .
-
Neuromodulation: A secondary analysis of the effects of θ-wave pulse transcranial magnetic stimulation on anger in veterans with post-traumatic stress disorder
Time of Update: 2021-07-27
It is further studied whether the improvement of anger is related to the reduction of the severity of post-traumatic stress disorder and depression symptoms and the improvement of sleep quality .
-
Neuromodulation: Transcranial AC stimulation can reduce neural network synchronization and persistent dizziness
Time of Update: 2021-07-27
Stimulus waveform and electric field distribution To determine the relationship between ASSR and MdDS symptom status, a group of MdDS patients was compared with an age-matched healthy control group, and the relationship between ASSR changes and transcranial alternating current stimulation (tACS) changes in the perception of oscillatory vertigo was determined .
-
Ann Neurol-Alzheimer's disease: brain function connection state, which can effectively predict cognitive ability
Time of Update: 2021-07-27
In this way, Sophie Dautricourt and others of the French National Academy of Medical Sciences used cross-sectional and longitudinal methods to study the changes in the functional connection of AT and PM networks in patients with amyloid β-positive MCI and Alzheimer’s disease, using separate MTL subregions.
-
JAMA Neurology-incidental intracranial hypertension, or lumbar puncture is not recommended
Time of Update: 2021-07-27
Signs of intracranial hypertension (IH) detected by magnetic resonance imaging (MRI), such as empty sella (empty sella), increased cerebrospinal fluid (CSF), optic nerve tortuosity, and rhabdominal sinus stenosis (TVSS), usually associated with idiopathic Intracranial hypertension (IIH) is related, but it is also present in patients with primary headache syndrome and asymptomatic patients .
-
Radiology: Evaluation of SSc-related ILD, we are one step closer
Time of Update: 2021-07-27
Recently, a study published in the Journal of Radiology developed a deep learning-based method that can detect lung collapse based on the elastic registration of chest CT images obtained during follow-up, thereby making an assessment of the deterioration of SSc-ILD.
-
Nat Commun: Polygenic risk score to identify high-risk individuals with Alzheimer's disease
Time of Update: 2021-07-27
Standardizing PRS with population averages instead of sample averages can make individual scores comparable in different studies.
-
JAMA Neurology-Mother taking antiepileptic drugs during pregnancy does not affect children's cognitive ability
Time of Update: 2021-07-27
Meador of Stanford University School of Medicine and others explored and compared 2-year-old children born to women with epilepsy (WWE) and healthy women , and used ASM plasma concentrations (ABLs) and doses to assess ASM exposure and WWE children’s neurodevelopment.
-
Cell Reports: After a severe seizure, microglia not only remove debris, but also heal damaged dendrites
Time of Update: 2021-07-27
In summary, the researchers recorded a microglia phenotype, which is called the microglia process pocket or MPP, which is strongly induced after a severe seizure, wraps around the beaded dendrites, and stabilizes Maintain for several hours to preserve their chemotaxis ability .
-
Neurology: Vitamin D supplementation can prevent benign paroxysmal positional vertigo
Time of Update: 2021-07-27
Recently, a blinded outcome evaluator, parallel, multi-center, randomized controlled trial initiated by a researcher evaluated the role of vitamin D and calcium supplements in preventing the recurrence of benign paroxysmal positional vertigo (BPPV).
-
JAMA Sub-Journal: "Alzheimer's Disease" is about to be renamed?
Time of Update: 2021-07-27
Two researchers screened studies containing data on the prevalence of dementia in people under 65 years of age for inclusion in a systematic review and meta-analysis .
-
JAHA: Efficacy Analysis of Endovascular Therapy in Patients with Acute Ischemic Stroke Disabled Before Stroke
Time of Update: 2021-07-27
9% of the patients in the medical treatment group achieved good outcomes (p<0.
Original source: Patients receiving EVT can achieve better functional outcomes than those receiving medical treatment .
-
NEJM: Let the paralyzed aphasia patient "speak" again?
Time of Update: 2021-07-27
If a product that directly decodes human nerve signals and converts them into language can be developed, it will greatly improve the quality of life for paralyzed patients who have lost their mobility due to illness .
-
Neuron: Scientists Reveal the Neural Circuits That Smoking Promotes Anxiety
Time of Update: 2021-07-27
In β2 type nAChR knockout mice, nicotine does not cause DA neurons in the VTA brain area to activate or inhibit the response, and there is no anxiety-like behavior; however, when β2 type nAChR is specifically expressed in the VTA region, nicotine can exert the above Effect .
-
Neurology-10,000 people followed up for 10 years: late-onset epilepsy, the mortality rate is higher than that of people without epilepsy
Time of Update: 2021-07-27
Many population-based studies have shown that compared with people without epilepsy, people with epilepsy ( diagnosed at any age ) have an increased mortality rate and an increased risk of seizure-related injuries , such as fractures, drowning, and motor vehicle accidents.
-
Neurology: In stroke patients with renal insufficiency, intensive antihypertensive treatment may be counterproductive!
Time of Update: 2021-07-27
The baseline eGFR of each eligible patient was calculated using the Chronic Kidney Disease Epidemiological Cooperation Equation .
-
JAMA Neurology-Tiantan Hospital’s new discovery: For moderate ischemic stroke, there is no difference in the effect of ticagrelor and aspirin combined with aspirin alone
Time of Update: 2021-07-27
In an exploratory subgroup analysis of the THALES trial, Wang Yongjun of Capital Medical University and others described the effectiveness of DAPT with ticagrelor plus aspirin in patients with acute ischemic stroke with a baseline NIHSS score of 4 or 5 in the first 30 days And safety .
-
Professor Wang Yongjun: Screening of suitable people for intravenous thrombolytic therapy for ischemic stroke (both charts are all done!)
Time of Update: 2021-06-30
In patients with intracranial artery dissection known or suspected that acute ischemic stroke is related to intracranial artery dissection, the usefulness and bleeding risk of intravenous r-tPA thrombolysis are unknown, uncertain, and unproven .
