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Alzheimer Dementia-Immune disorders are associated with early cognitive decline
Time of Update: 2021-08-03
Genome-wide association studies ( GWAS ), Alzheimer's disease (AD) animal models, and neuropathological studies jointly support the central role of immune disorders in AD and cognitive decline in later life .
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Neurology-Strengthening blood pressure leads to kidney damage and worse prognosis
Time of Update: 2021-08-03
In patients with ICH, the second acute intracerebral hemorrhage intensive blood pressure test (INTERACT2) showed that compared with the standard, intensive blood pressure had a moderate improvement in functional results; its post-mortem analysis showed that the effects of early intensive blood pressure reduction were different It is consistent in eGFR .
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Alzheimer's & Dementia: Individual brain atrophy can predict the onset of dementia in dominant Alzheimer's disease
Time of Update: 2021-08-03
Increase the prediction rate beyond the established method of age Increase the prediction rate beyond the established method based on the family age of onsetTherefore, this individualized risk score based on brain atrophy can be used to establish the selection criteria for prevention trials and the stratification of DIAD-MC participants .
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NEJM: Directly decode cortical activity to restore the language function of stroke paralyzed patients
Time of Update: 2021-08-03
This study is the first realization that in patients with paralysis caused by brainstem stroke, by using deep learning models and natural language models to directly decode cortical activity to restore the patient’s language function .
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IEEE trans: The relationship between emotional state, sleep quality, and resting state EEG: a research for graduate students
Time of Update: 2021-08-03
In order to study the electrophysiological correlation of students' mental state changes over time, during the entire research process, the resting state EEG signals and the depression, anxiety and stress scale (DASS) of the participants in multiple experimental sessions were recorded .
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Have you learned the basic skills of image reading of brain lesions?
Time of Update: 2021-08-03
Preciseu Focus on the clinical application research of new CT and MRI imaging technologies, especially the central nervous system diseases; the clinical application of magnetic resonance guided ultrasound focused knife (MRgFUS) in the treatment of uterine fibroids, adenomyosis and bone metastasis pain, etc.
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JNNP: Retrospective analysis of the relationship between rehabilitation intensity and rehabilitation after stroke
Time of Update: 2021-08-03
It was observed that this improvement was proportional to the training intensity, that is, compared with the two low-intensity groups, the high-intensity group showed higher treatment responsiveness at all measurement points (H-CT and L-CT/L -Reactivity difference between RGS; mean 4±1 SE represents subacute; SE means early chronic; mean 5±1 SE means late chronic; mean 6±1; p<0.
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JNNP-How does age affect the incidence of intracerebral hemorrhage?
Time of Update: 2021-08-03
Prevent stroke diabetes cholesterolSo far, compared with ischemic stroke, only a few studies have investigated whether the influence of these risk factors on the occurrence of intracerebral hemorrhage (ICH) changes with age, especially whether there is a difference between early-onset disease and late-onset disease .
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JNNP: GFAP as a biomarker for frontotemporal dementia and primary mental illness: diagnosis and prognostic performance
Time of Update: 2021-08-03
The relationship between sGFAP levels and C9orf72 repeat expansion (because it is related to astrocyte proliferation), survival time of FTLD patients, and cross-sectional and longitudinal brain atrophy of FTLD and PPD patients were evaluated .
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Neuromodulation: Stimulation of the dorsal root ganglion on the spinal cord ascending effect in patients with chronic pain
Time of Update: 2021-08-03
Neuromodulation: Technology at the Neural Interface Aziz , TZ and Green, AL (2021 ), supraspinal Effects of Dorsal Root Ganglion Stimulation in Chronic Pain Patients in this message
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Neurology-C reactive protein, or involved in AD neurodegeneration
Time of Update: 2021-08-03
Only in participants with two APOE ε4 alleles, increased CRP was associated with decreased MMSE at baseline and 12-month follow-up .
The interaction between the two APOE ε4 alleles and the increase in plasma CRP is associated with t-Tau (β = 11.
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Neurology-Automatic biochemical analysis of cerebrospinal fluid to help diagnose Alzheimer's
Time of Update: 2021-08-03
It has been proven to be able to distinguish AD from other neurodegenerative diseases, and its diagnostic accuracy is comparable to CSF and PET-based tau pathological measurements .
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Neurology-Parkinson's disease, neuromelanosis, affect sports or cognitive ability, anatomical location is the key!
Time of Update: 2021-08-03
Neuromelanosis of LC is related to cognitive function in all test areas, but not related to dyskinesia or activities of daily living .
Association of Locus Coeruleus and Substantia Nigra Pathology With Cognitive and Motor Functions in Patients With Parkinson Disease.
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Nat Commun: The concentration of p-tau181 in plasma can be used as a potential biomarker for Alzheimer's disease in patients with Down syndrome
Time of Update: 2021-08-03
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome.
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome.
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JNNP: Spontaneous resolution of cervical thoracic syringomyelia after significant weight loss
Time of Update: 2021-08-03
Her neurological symptoms have also improved, and the MRI of the spinal cord nerve axis shows that the cervical thoracic syringomyelia is in stable condition .
One year later, the patient's neurological symptoms were relieved, and the MRI of the spinal cord nerve axis showed that the cavity had almost completely subsided .
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Ann Neurol-New study finds genetic risk sites for cluster headaches
Time of Update: 2021-08-03
Through GWAS , the genetic risk locus of cluster headache was discovered and replicated, and its effect size is larger than that usually seen in complex genetic diseases .
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Neurology-temporal lobe epilepsy, surgery may slow down brain aging
Time of Update: 2021-08-03
Christophe E de Bézenac of the University of Liverpool in the United Kingdom and others explored the impact of neurosurgery on BrainAGE as a measure of overall brain health, and compared 48 mTLE patients before and after surgery with 37 control groups .
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Alzheimer's & Dementia: Research has identified 11 candidate gene variants for Alzheimer's disease
Time of Update: 2021-08-03
The Alzheimer's & Dementia study identified 11 rare Alzheimer's disease candidate variants .
Teerlink et al, Analysis of high-risk pedigrees identifies 12 candidate variants for Alzheimer's disease, Alzheimer's & Dementia (2021).
Teerlink et al, Analysis of high-risk pedigrees identifies 12 candidate variants for Alzheimer's disease, Alzheimer's & Dementia (2021).
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Alzheimer&Dementia: Be alert!
Time of Update: 2021-08-03
Western diet and psychosocial stress can cause pathological changes and increase the risk of AD-related neuropathology, while the Mediterranean diet may protect the brain .
Western diet and psychosocial stress can cause pathological changes and increase the risk of AD-related neuropathology, while the Mediterranean diet may protect the brain .
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Stroke: Machine learning algorithms significantly improve the accuracy of CRP levels in predicting the prognosis of subarachnoid hemorrhage
Time of Update: 2021-08-03
Subarachnoid hemorrhage (SAH) refers to brain lesions or bottom surface of the brain blood vessels rupture, blood flow directly into a clinical syndrome caused by subarachnoid space, accounting for acute cerebral stroke 10%, it is a very serious common Disease .
