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Diabetes Care: Weight loss depends on your brain!
Time of Update: 2021-08-27
references:Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study.
2337 /dc20-2641Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study.
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Stroke: After analyzing 200,000 people, what is the general situation of mechanical thrombus removal after stroke?
Time of Update: 2021-08-26
The nursing system should provide extensive and timely thrombectomy for patients with ischemic stroke and large vessel occlusion .
The nursing system should provide extensive and timely thrombectomy for patients with ischemic stroke and large vessel occlusion .
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Cell Sub-Journal: Feng Guoping's team reveals the shared pathogenic mechanism behind autism and schizophrenia
Time of Update: 2021-08-24
On June 30, 2021, the team of Professor Guoping Feng from the Massachusetts Institute of Technology published a research paper titled Anterior Thalamic Dysfunction Underlies Cognitive Deficits in a Subset of Neuropsychiatric Disease Models in Neuron.
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Lan Xiao, Jianqin Niu, and collaborator AS from Army Military Medical University: The mechanism of the development of astrocyte network regulated by oligodendrocytes in early stress mental behavior
Time of Update: 2021-08-24
Advanced Science recently published the research results jointly discovered by Professor Niu Jianqin and Xiao Lan of the Army Military Medical University and researcher Yi Chenju from the Seventh Affiliated Hospital of Sun Yat-sen University "Reduced oligodendrocyte precursor cell impairs astrocytic development in early life stress" (DOI: 10.
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How Nature's gut microbiota affects social behavior through stress neurons
Time of Update: 2021-08-24
The results showed that compared with SPF mice, GF and ABX mice had a more significant increase in serum corticosterone levels after brief social contact, and this change was not affected by the circadian rhythm .
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Why is there a memory impairment?
Time of Update: 2021-08-24
Researchers have revealed through mouse studies that some genes that are mutated or missing in patients with autism or schizophrenia cause similar neural circuit dysfunctions in the thalamus "by different routes" .
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Neuron Feng Guoping's team reveals that different neuropsychiatric diseases share pathogenic mechanisms
Time of Update: 2021-08-23
"Professor Feng Guoping said that this study reveals a new loop mechanism that regulates cognitive impairment, and also suggests that in the future development of new treatment methods, patients can be treated through biological pathogenesis rather than through different diseases.
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[Nature Sub-Journal] Authority!
Time of Update: 2021-08-23
They found that whether a brain has good malleability is related to the ability of methyl groups attached to DNA to activate genes .
The malleable brain, this "epigenetic mark", will decrease with age, but for animals in a living environment with high stimulation intensity, the decrease in methyl groups is relatively small .
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Less is more, the secret of the brain's "low energy consumption" and "efficient response": modular NSR
Time of Update: 2021-08-23
The key to the "low energy consumption and high efficiency" of the brain network is that the neural connections are sparse in the global, but tight in the local area, forming a modular structure, which in turn changes the dynamic properties: the local modularity greatly reduces the total amount of connections used to establish connections.
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Nature Sub-Journal: Born in sorrow and dying in comfort, a stimulating environment will keep the brain young
Time of Update: 2021-08-23
Through single-nucleotide resolution whole-genome DNA methylation sequencing, it is proved that high stimulation environment can also restore a large number of age-related DNA methylation changes in the hippocampus of the brain .
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Nature｜Will not make friends, or originate from intestinal flora!
Time of Update: 2021-08-21
Transplanting the intestinal flora of SPF-grade normal mice into sterile mice can significantly improve social disorders and reduce corticosterone levels .
Chronic chemogenetic inhibition of corticotropin releasing hormone (CRH) neurons in the PVN brain region can reverse the social disorder of ABX mice and reduce the level of corticosterone .
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The modularity and robustness of the Cell brain
Time of Update: 2021-08-21
To answer this question, the authors in this study performed recordings of the electrical activity of large-scale neuronal populations and optogenetic disturbances in the prefrontal cortex on both sides of the brain when the mice were performing short-term memory behavioral tasks .
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Today's "Science" has found a new type of brain cell, without which it may be blind!
Time of Update: 2021-08-21
▲The temporal pole area (red and yellow) is involved in facial recognition (picture source: Reference [2]; Credit: Sofia Landi) Moreover, the researchers also observed a very interesting phenomenon: even with the screen to these monkeys Playing the faces of strangers many times, they still react more strongly to acquaintances they have seen in the real world .
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Neuron｜Highly selective intestinal-brain axis dialogue mechanism-the micro-neural circuit of vagus neurons
Time of Update: 2021-08-21
Two subtypes of DMV neurons, Cck+ and Pdyn+ innervate the same area of the digestive system, but form nerve fiber structures around different enteric neurons .
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Chinese Scientist Cell Article Revealed: Why can you remember the girl's mobile phone number?
Time of Update: 2021-08-19
In this study, when the mice were performing short-term memory behavioral tasks, they also recorded large-scale "neuronal population electrical activities" and "optogenetic disturbances" in the prefrontal cortex on both sides of their brains .
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[Nature] Neural connection between intestinal flora and social behavior
Time of Update: 2021-08-19
The research team led by Wu Wei-Li, a postdoctoral fellow in the former Mazmanian laboratory, aims to identify neurons that are affected by corticosterone and play a role in social behavior .
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Adv Sci Niu Jianqin/Xiao Lan's collaborative team reveals the mechanism of the development of astrocyte network regulated by oligodendrocytes in early stress mental behavior
Time of Update: 2021-08-17
This thesis uses a variety of conditions to knock out mice, combined with techniques such as behavior, immunofluorescence staining, and fluorescence bleaching recovery, and found that the reduction of oligodendrocyte progenitor cells (OPC) in the early isolation of the mouse brain can inhibit astrocytes The development of plasma cells and astrocyte network affects the activation of neurons .
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Mol Psychiatry︱ Frontier Review: The latest progress in the molecular mechanism of ketamine against depression
Time of Update: 2021-08-17
Lijia Chang and Professor Kenji Hashimoto (corresponding author) of the Social and Mental Health Education Research Center of Chiba University The molecular mechanisms of antidepressant and derivatives, and discussed the brain-gut axis, brain-spleen axis in stress-related depression and the role of R-ketamine in antidepressant.
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I am depressed, am I drinking?
Time of Update: 2021-08-17
The activation of CRH neurons can alleviate social barriers caused by chronic stress and reduce aggressive behavior .
In general, this article simulates the poorly adaptive behaviors of women under continuous stress through animal models, revealing that the CRH neurons in the front of the central medial thalamus are the key neurons for mood disorders to promote alcohol use .
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Nature Genetics functions expanded again!
Time of Update: 2021-08-16
The study defines SPTBN1 variants as the genetic basis of neurodevelopmental syndrome, expands the spectrum of spectrin diseases that affect the brain, and emphasizes the key role of βII-spectrin in the central nervous system .
