-
Neurology: Interdisciplinary breakthrough in artificial intelligence: asymptomatic cerebrovascular disease, which can effectively predict future strokes
Time of Update: 2021-08-27
Silent cerebrovascular disease (SCD) consists of silent cerebral infarction (SBI) and white matter disease (WMD), and is usually found incidentally on neuroimaging scans obtained during routine clinical care .
There is no screening for asymptomatic cerebrovascular diseases in routine care .
-
Stroke: Attention!
Time of Update: 2021-08-27
The main hypothesis: Patients with OCD, especially the elderly, have an increased risk of new strokes during the follow-up period compared to non-OCD controls .
-
JNNP: Plasma NfL level and longitudinal change rate of C9orf72 and GRN-related diseases: from customized reference to clinical application
Time of Update: 2021-08-27
NfL levels change in presymptomatic carriers (PS) of FTD/ALS-related mutations, 2-5 years earlier than fully symptomatic disease .
165 neurological health controls evaluated 101 C9orf72 and 86 GRN mutation carriersIn the patient group, the median age of onset (AAO) was 58.
-
JAHA: Is there a difference in the risk of stroke after acute and elective cardioversion in patients with atrial fibrillation?
Time of Update: 2021-08-27
Stroke Recently, the heart blood vessels published on the prestigious journal JAHA the areas of disease research article, the researchers included all patients with acute or elective ECV for the first time during the 2011-2018 health care database in the Stockholm area, and missing 30 days after ECV Cox regression analysis was performed for strokes with bloody or unclear etiology, and the CHA2DS2-VASc score, drug treatment, and inclusion year were adjusted .
-
Heavy: Stroke survivors, exercise more, can greatly reduce all-cause mortality
Time of Update: 2021-08-27
Joundi and others of the University of Calgary in Canada conducted a population-based study using the Canadian Community Health Survey (CCHS) linked to an administrative database to assess: compared with the control group, stroke survivors’ The relationship between PA and long-term mortality risk, while taking into account functional limitations and assessing the difference with age .
-
Alzheimers Dementia: Screening of 5000 plasma proteins, which ones can predict the risk of dementia?
Time of Update: 2021-08-27
In addition, longitudinal studies have shown that most cognitively normal amyloid-positive people never develop clinical dementia .
For several reasons, circulating proteins are promising targets for biomarker and drug discovery .
Animal studies support the causal role of circulating plasma proteins in neurodegeneration .
-
60% of patients with cerebrovascular disease have hidden onset, how to make early diagnosis, prevention and treatment?
Time of Update: 2021-08-27
consensus Cerebral Small Vascular Disease (CSVD) is a common disease that seriously endangers the health of our people.
Metz Medicine invited the director of the First Affiliated Hospital of Harbin Medical University [Zhang Zhongling] to give online lectures to deeply analyze the clinical features and prevention and treatment of cerebral small blood vessels.
-
JAMA Sub-Journal: Data of 1 million people from Wang Yongjun’s team suggests that the clinical characteristics, management and efficacy of stroke patients in China
Time of Update: 2021-08-27
In China, in order to improve the compliance of patients with acute ischemic stroke (IS) to evidence-based performance measures and in-hospital results, a multi-faceted quality improvement intervention has been formulated and implemented .
-
Nature: The brain-fat circuit controls obesity
Time of Update: 2021-08-27
Obesity is caused by excessive accumulation of lipids, which can be used as a source of high energy during periods of dietary deprivation . Existing studies have shown that signals from sympathetic n
-
Stroke: After a stroke, the use of fluoxetine for 6 months will affect the functional prognosis
Time of Update: 2021-08-27
. Recently, AFFINITY (Evaluation of Fluoxetine in Stroke Recovery) reported that in 1280 acute (2-15 days) stroke patients, oral fluoxetine, 20 mg per day, for 6 months after acute stroke, and placebo In contrast, it did not improve the functional outcome at 6 months and increased the risk of falls, fractures and seizures .
-
Neurology: Multiple sclerosis, age and contrast enhancement damage are closely related
Time of Update: 2021-08-27
They used the original trial data of the CombiRx cohort, namely the RRMS trial, the ASCEND SPMS trial, and the PROMISE and INFORMS trials of primary progressive multiple sclerosis to describe the ages of the entire trial cohort at baseline and one year later in the treatment group.
-
JNNP: Asymptomatic progression of brain atrophy in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder
Time of Update: 2021-08-27
The NWV of MRI-1 and MRI-2 in AQP4+NMOSD patients was higher, but there was no difference in the annual atrophy rate of NGV, NWM and NBV between the two patient groups .
-
Eur Heart J: Be wary of poor sleep and increased risk of heart failure!
Time of Update: 2021-08-27
Recently, the heart blood vessels magazine published a leading authority Eur Heart J a research article, researchers to investigate changes over time insomnia (difficulty falling asleep, difficult to maintain sleep, wake up early in the morning, non-restorative sleep) between HF Vertical association .
-
Alzheimers Dementia: New image scores to help predict cognitive ability
Time of Update: 2021-08-27
So far, there are relatively few comparisons between data-driven and hypothesis-driven MRI indexes, especially in different cohorts, as indicators for predicting event-related cognitive impairment .
These scores were compared with a hypothesis-driven volumetric measurement method based on several brain regions susceptible to AD, as predictors of cognitive impairment events in different situations .
-
JAMA Sub-Journal: How important is it that people around you listen to you "Tucao"?
Time of Update: 2021-08-27
In summary, social support in the form of supportive listening is related to greater cognitive resilience, and it independently changes the association between lower total brain capacity and poor cognitive function .
references:Association of Social Support With Brain Volume and Cognition.
-
Heart: Non-vitamin K oral anticoagulant and glucocorticoid combined treatment of gastrointestinal bleeding risk in patients
Time of Update: 2021-08-27
Compared with patients who only use NOACs, simultaneous treatment with NOACs and oral glucocorticoids is associated with an increased short-term incidence and risk of GIB .
-
Diabetes Care: Weight loss depends on your brain!
Time of Update: 2021-08-27
references:Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study.
2337 /dc20-2641Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study.
-
JNNP: Long-term psychogenic non-epileptic seizures misdiagnosed as status epilepticus: epidemiology and related risks
Time of Update: 2021-08-27
Partial seizuresBecause the clinical distinction between epileptic seizures and PNES requires specific expertise, and the treatment of status epilepticus requires almost immediate decision-making, misdiagnosis is prone to occur in the emergency environment, and PPNE is often wrongly treated with non-indication drugs.
-
Hypertension: Long-term blood pressure variability increases the risk of dementia and cognitive decline
Time of Update: 2021-08-27
Follow-up dose-response relationship between systolic blood pressure variability (SBPV) and dementia and cognitive impairmentThe researchers identified a total of 5919 papers, including 16 longitudinal studies, with a total of 7 million participants.
Long-Term Blood Pressure Variability Increases Risks of Dementia and Cognitive Decline: A Meta-Analysis of Longitudinal Studies .
-
JNNP: The comparative significance of different clinical scales in evaluating hereditary frontotemporal dementia
Time of Update: 2021-08-27
The CDR+NACC FTLD global rating is determined using the published scoring rules, which are based on the severity of the eight areas and are scored on a five-point scale (0, 0.
First, the CDR+NACC FTLD global score was used to determine the disease severity of mutation carriers.
