-
Nature Sub-Journal: Comparable to optogenetics, magnetic thermal nanotechnology non-invasive treatment of Parkinson's
Time of Update: 2021-09-30
On September 22, 2021, Maastricht University Medical Center Yasin Temel's research team used non-invasive magnetic thermal deep brain stimulation technology to improve the motor symptoms of Parkinson's model mice .
-
These 10 drugs can induce dementia, use with caution!
Time of Update: 2021-09-30
3 The anti-epileptic drugs phenytoin and carbamazepine can inhibit the electrical conduction of the nerve membrane on average, and proper dosage has obvious therapeutic effect on senile epilepsy and epilepsy caused by traumatic brain injury, but overdose or medication for too long will reduce intelligence; Although drugs such as Jingning and Ethosuximide have certain anti-epileptic effects, long-term use can aggravate symptoms of senile dementia, as well as apathy and confusion .
-
Professor Jin Tao: A new treatment option for multiple sclerosis under the new pattern NCN2021
Time of Update: 2021-09-30
In the phase III clinical trial F203/204, the proportion of patients who responded to Fampridine sustained-release tablets treatment with T25FW (timed 25-foot walk) improved was 38%, which was significantly better than the placebo group (Figure 10) .
-
Today's "Nature": Exploring the mystery of a hundred years of memory, why some smells always remind people of the past
Time of Update: 2021-09-30
▲The location of sector cells in the mouse brain (picture source: Reference [2]) The researchers used electrophysiological recording and optogenetic methods to record the activity of the sector cells in mice, and found that when the mice learned to be unrelated to the original The fan-shaped cells play an important role when the specific scent of scent is associated with reward .
-
"Guidelines for Primary Diagnosis and Treatment of Ischemic Stroke (2021)" released!
Time of Update: 2021-09-30
The active participation of primary general practitioners in comprehensive prevention and treatment is one of the key measures to control ischemic stroke .
④Patients with hypotension after ischemic stroke should actively search for and deal with the cause, and if necessary, use expansion and pressure increase measures .
-
Mov Disord: Parkinson's patients have rapid eye movements at the same time, and the clinical progress is faster
Time of Update: 2021-09-29
Parkinson's disease + pRBD patients progress faster in motor, mood, and cognitive symptoms Original Source: Liu Y, Lawton MA, Lo C, et al.
Longitudinal Changes in Parkinson's Disease Symptoms with and Without Rapid Eye Movement Sleep Behavior Disorder : The Oxford Discovery Cohort Study.
-
PLOS ONE: Overcoming social fear, social interaction helps improve the cognitive function of the elderly!
Time of Update: 2021-09-29
Recently, researchers from Pennsylvania State University's Center for Healthy Aging found that 70 70 Zhi 90 90 years or older have more frequent and enjoyable social interaction, and the next two days they have better cognitive performance on the day .
-
JNNP: Is diffusion tensor MRI a predictor of dementia?
Time of Update: 2021-09-29
An optimized multimodal MRI marker was established as a surrogate marker for the (optimal) test of vascular cognitive impairment caused by cerebral small vessel disease to determine whether DTI measurement can predict SVD dementia in multiple cohorts .
-
Neurology: Survival rate of colorectal cancer in patients with multiple sclerosis
Time of Update: 2021-09-29
Researchers aim to use a retrospective matched cohort design to test the following hypothesis: that is , the overall and cancer of multiple sclerosis (MS) patients after the diagnosis of colorectal cancer The specific survival rate is lower than that of patients without MS .
-
Alzheimer Dementia: How do patients with cognitive impairment make decisions about medical and nursing costs?
Time of Update: 2021-09-29
The important significance of this study is that it has found that the cost-effectiveness of managing /changing MCI and dementia should be considered at the end of life and the intensity of NH use .
-
JAMA Neurology: How does the length of sleep affect cognitive function?
Time of Update: 2021-09-29
The important significance of this study lies in the findings: Both short and long sleep time are related to worse results in the elderly , such as greater Aβ burden, greater depressive symptoms, higher body mass index, and cognitive decline.
-
JAMA Psychiatry: Hypothyroidism may cause depression!
Time of Update: 2021-09-29
Hypothyroidism is considered to be the cause of depression or a strong risk factor Hypothyroidism is considered to be the cause or strong risk factor of depressionIn order to assess the association between hypothyroidism and clinical depression in the general population, experts from the Department of Psychiatry and Psychotherapy at the University of Cologne Medical School in Germany conducted a meta-analysis study, and the results were published in the recent JAMA Psychiatry journal .
-
Neurology: the relationship between atrial fibrillation, stroke and asymptomatic cerebrovascular disease
Time of Update: 2021-09-29
Blood vesselRecently, an authoritative journal in the field of neurology published a research article in Neurology, which aims to determine whether AF is associated with a wide range of cerebrovascular diseases, not just the known association with symptomatic stroke , including asymptomatic Markers of infarction and small vessel disease, such as cerebral microhemorrhage (CMB), white matter hyperintensity (WMH), and lacunar infarction in samples from a 70-year-old population .
-
JAMA Neurol: Suicide risk assessment for patients with 5 new anti-epileptic drugs (eslicarbazepine, perampanel, brivaracetam, cannabidiol and cenobamate)
Time of Update: 2021-09-29
Manage FDAResearchers in Epilepsy recently reviewed data from 10 clinical phase II-III studies of ASM approved for marketing after 2008 to evaluate the effect of these drugs on patients' suicide risk compared with placebo .
-
Mov Disord: In Parkinson's patients, how does the mortality rate change over time?
Time of Update: 2021-09-29
After adjusting for age, sex, and time after diagnosis, compared with people without PD (5% per year; 95% CI: 3%-6%), the mortality rate of PD patients decreased more from 2007 to 2016.
-
Neurology: The relationship between serum neuroserine and the progression of relapsing-remitting multiple sclerosis patients treated with natalizumab
Time of Update: 2021-09-29
In the course of the disease evolution of 10-15 years, the progressive irreversible disability that occurs in most patients is largely independent of acute focal inflammatory activities, including recurrence and new MRI damage .
-
Neurology: What are the unique manifestations of MRI for hereditary frontotemporal dementia?
Time of Update: 2021-09-29
However, most previous studies have focused on purely cognitive phenotypes, and extensive descriptions of subcortical and cerebellar injuries in each genetic form of the FTD/MND spectrum (including C9orf72-related diseases) are still in progress .
-
Brain Health Day: Take good care of the brain and strive for brain health
Time of Update: 2021-09-29
● In terms of diet, the Mediterranean diet is currently recommended , because the eating habits of residents of Mediterranean countries can not only protect their heart health, but also help keep their brains young and healthy .
-
Neurology: Biomarkers for the detection of atrial fibrillation after stroke: a systematic review and meta-analysis
Time of Update: 2021-09-29
Stroke Long-term heart monitoring can help detect more atrial fibrillation .
The HAVOC and AS5F scores are designed to use clinical variables to predict post-stroke atrial fibrillation, but are limited by moderate predictive value and external validation .
-
Neurology: gradual freezing syndrome, abnormal eye movements or predictable cognitive changes
Time of Update: 2021-09-29
However, in ALS patients, the frequency of clinically significant OMAs found through standard neurological examinations rather than quantitative video oculographic measurements , and their relationship to underlying motor and cognitive phenotypes are still unknown .
