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JAMA: Cerebral infarction is treated with endovascular treatment, should it be combined with alteplase?
Time of Update: 2021-10-11
Only for medical professionals to read and refer to clinical information, 1s to reach more cutting-edge clinical information, follow the clinical pharmacy channel to obtain the source of this article
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How to diagnose and treat the easily overlooked culprit of dementia "frontotemporal degeneration"?
Time of Update: 2021-10-11
FTLD is a group of neurodegenerative diseases characterized by selective progressive atrophy and degeneration of the frontal and/or temporal lobes, which are clinically, pathologically and genetically heterogeneous .
From the clinical phenotype, the frontotemporal lobe degeneration spectrum disease includes the following 7 types: (1) Amyotrophic lateral sclerosis: amyotrophic lateral sclerosis, ALS .
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The guidelines for blood pressure management in stroke prevention and treatment can be found here!
Time of Update: 2021-10-11
Figure 2 Management process in the acute phase of stroke 03 Blood pressure management guidelines for secondary prevention of stroke The blood pressure should be closely monitored in the acute phase of stroke to reduce the incentives for blood pressure fluctuations .
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How do humans consolidate memory?
Time of Update: 2021-10-11
The brain imaging results show that a neural network representing the behavior sequence that people are learning will reactivate and replay quickly and repeatedly at a speed of 20 times during the rest interval of the exercise, thereby strengthening and consolidating this memory .
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Sleep more and less than sleep well
Time of Update: 2021-10-11
Multivariate logistic regression analysis explored the impact of sleep quality and sleep duration on the post-stroke depression .
Table 2 Multi-factor analysis summary of the influence of sleep duration and sleep quality on post-stroke depression.
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Brain︱ new method!
Time of Update: 2021-10-11
, Brain 2021; awab332) In order to further study the effect of small vessel disease on plasma sTREM2 levels in the presence of amyloid and tau protein lesions Impact .
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31-year follow-up study: To improve brain and heart health, pay attention to these points while you are young!
Time of Update: 2021-10-11
Compared with people of normal weight, those who are obese for life have a decline in their ability to process visual information or maintain attention as they age .
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Express develops small molecule therapies targeting RNA, Xinwei receives 80 million US dollars in assistance
Time of Update: 2021-10-10
The funds will be used to advance the small molecule drug platform (SMiRNA) targeting RNA to discover the treatment of myotonic muscular dystrophy type 1 (DM1), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and more A drug candidate for tauopathies .
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Stroke: Patients with hypertrophic cardiomyopathy based on the presence or absence of ischemic stroke in atrial fibrillation
Time of Update: 2021-10-10
Patients with hypertrophic cardiomyopathy (HCM) have a high risk of ischemic stroke (IS), especially in the presence of atrial fibrillation (AF) .
The researchers used the Logistic regression model to construct the French HCM score and compared it with the HCM risk-CVA and CHA2DS2-VASc scores using the c-index and calibration analysis .
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JNNP: Early predictor of disability in children due to serum AQP4 IgG positive neuromyelitis optica spectrum disease
Time of Update: 2021-10-10
Subsequently, information on gender, age of onset, race, type of onset and immunosuppressive treatment, time to first relapse, time to long-term visual disability (best visual acuity less than 6/36, duration of more than 6 months), dyskinesia (walking ) ≤ 500 meters long, unassisted for more than 6 months, extended disability status scale (EDSS) score) and cognitive impairment (defined by neuropsychological assessment or documented learning disability, requiring additional support from the school) .
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Stroke: In patients with hypertrophic cardiomyopathy, ischemic stroke is related to atrial fibrillation
Time of Update: 2021-10-10
In patients with atrial fibrillation, the CHA2DS2-VASc score has a marginal improvement over the HCM Risk-CVA score, but it is less predictive than the French HCM score (P=0.
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Courier pouch obtains potential "first-in-class" therapy, AstraZeneca acquires cutting-edge for US$500 million
Time of Update: 2021-10-10
▎Editor of WuXi AppTec's content team On September 29, 2021, AstraZeneca announced that its subsidiary Alexion has acquired Caelum Biosciences and obtained the treatment CAEL-101, which is in phase 3 clinical development .
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Stroke: How to quickly classify upper limb symptoms for stroke?
Time of Update: 2021-10-10
This retrospective analysis only included and scored ARAT tasks that were feasible in video calls, because we wanted to ensure that the resulting FOCUS (Fast Upper Extremity Classification after Stroke) assessment might be carried out remotely .
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JNNP: Will the new coronavirus infection increase the risk of anxiety or depression infection?
Time of Update: 2021-10-10
The data of 413,148 non-medical staff users were counted, a mental health survey was answered from February to April 2021, and the SARS-CoV-2 test results were reported .
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The Lancet Global Stroke Report: 1 out of 4 people over the age of 25 will have a stroke
Time of Update: 2021-10-10
The 2017 Global Burden of Disease, Injury, and Risk Factors Study (GBD) showed that stroke is the world's second leading cause of death and the third leading cause of disability (measured by disability-adjusted life years [DALYs]) .
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BMJ: Don't just eat!
Time of Update: 2021-10-10
16,291 (14%) women diagnosed with dementia and 68,726 (14%) control group had used menopausal hormone therapy more than three years before being included in the study .
references:Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases.
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Nature Sub-Journal: The largest study so far reveals a new genetic locus of Alzheimer's disease
Time of Update: 2021-10-10
On September 7, 2021, the research team of the Vrije Universiteit Amsterdam published a research paper titled: A genome-wide association study with 1,126,563 individuals identifying new risk loci for Alzheimer's disease in the journal Nature Genetics .
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Stroke: The complex characteristics of the pathological mechanism of cerebrovascular disease and its relationship with cognitive decline
Time of Update: 2021-10-10
When viewed as two different groups, the mixed CVD feature group (but not the single CVD feature group) showed faster cognitive decline in all areas of assessment compared to the dead without CVD neuropathology .
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Stroke: The impact of delirium on the prognosis of patients with cerebral hemorrhage
Time of Update: 2021-10-10
Delirium predicts a worse prognosis for patients with intracerebral hemorrhage (ICH), but it is not clear whether symptom relief or the intensity of treatment after the acute phase can reduce its effects .
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Huang Chaoyang: Interview with a "flame" expert who extinguishes the anxiety of neurology patients · Issue 6
Time of Update: 2021-10-10
Introduction In neurology clinics and wards, patients with significant anxiety symptoms are quite common, including patients secondary to neurological diseases (such as stroke, Parkinson’s disease, epilepsy), and various physical discomforts (such as insomnia, headaches) , Dizziness) patients with primary anxiety who are the chief complaint .
