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ENVIRON HEALTH PERSP: Common chemicals in electronics and baby products can impair brain development
Time of Update: 2021-10-20
. Reference materials:Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers, Environmental Health Perspectives (2021).
1289/EHP9285Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers, Environmental Health Perspectives (2021).
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Stroke: Delirium after a stroke, what changes in the brain network
Time of Update: 2021-10-20
Little is known about ARAS and the function of attention and orientation networks in stroke patients at risk of SN and delirium.
To assess the relationship between the global functional connectivity of the four right hemibrain seed areas in the cortical-subcortical arousal and attention network and effective measures of SN and delirium severity .
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JAMA N: RCT that bypasses the emergency room and CT room and sends the patient directly to the radiography room
Time of Update: 2021-10-20
The time from admission to arterial puncture (door-to-puncture [door-to-puncture, DTP]) in the emergency room is a widely used performance indicator to evaluate the effectiveness of the workflow in the hospital, and it has been shown to be related to clinical outcomes .
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stroke: Acute stroke, endovascular treatment has many benefits
Time of Update: 2021-10-19
van den Berg of the University of Amsterdam and others evaluated whether endovascular treatment plus conventional care is cost-effective compared with conventional care alone in patients with acute ischemic stroke .
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Interpretation of the 2021 European Narcolepsy Guidelines, comments on breakthrough treatment plans
Time of Update: 2021-10-11
In 2021, the European Society of Neurology (EAN), the European Society for Sleep Research (ESRS) and the European Narcolepsy Collaborative Group (EU-NN) ) Jointly issued the European Narcolepsy Guidelines, providing the latest clinical recommendations based on evidence-based medicine for the treatment of the disease .
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The first "Shanghai Expert Recommendations for Blood Pressure Management of Inpatients with Ischemic Stroke" is released today!
Time of Update: 2021-10-11
➤It is recommended that all patients with ischemic stroke and high blood pressure should undergo ambulatory blood pressure monitoring before discharge to evaluate the effect of antihypertensive treatment during hospitalization and to guide good blood pressure management during secondary prevention after discharge .
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Professor Liu Ming: Five difficult problems in the clinical diagnosis and treatment of acute stroke and their solutions!
Time of Update: 2021-10-11
*For medical professionals to read and refer to the NCN 2021 exciting content express, don’t miss the 24th National Neurology Conference of the Chinese Medical Association in September 2021, Professor Liu Ming from West China Hospital of Sichuan University, for us Put forward the main difficulties and related problems in the clinical diagnosis and treatment of acute stroke, and bring us corresponding solutions and countermeasures.
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A list of recommendations for the management of blood lipids in the prevention and treatment of stroke!
Time of Update: 2021-10-11
For non-cardiogenic ischemic stroke/TIA patients, regardless of other evidence of atherosclerosis, long-term treatment with statins is recommended to reduce the brain The risk of stroke and cardiovascular events; the recommended target value of LDL-C is less than 1.
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BMJ: It's best to use your brain at work!
Time of Update: 2021-10-11
Based on research data spanning Europe and the United States, covering 100,000+ participants, they found , People who work with high cognitive stimulation are at a lower risk of developing dementia than those who work with low cognitive stimulation .
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Multi-targeted drug DREAM Challenge: A "crowdsourcing" drug screening program for RET-driven tumors and Tau protein neurodegenerative diseases
Time of Update: 2021-10-11
On September 14, 2021, the research group of Jiang Hualiang and Zheng Mingyue from the Institute of Immunochemistry of Shanghai University of Science and Technology/Shanghai Institute of Materia Medica of the Chinese Academy of Sciences published the title Crowdsourced identification of multi-target kinase inhibitors for RET- as co-authors in PLOS Computational Biology.
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Adv Sci Sun Lei's team achieves precise neuroregulation of deep brain regions in mice
Time of Update: 2021-10-11
On September 21, 2021, Sun Lei's team from Hong Kong Polytechnic University published an article Precise Ultrasound Neuromodulation in a Deep Brain Region Using Nano Gas Vesicles as Actuators in Advanced Science, using low-frequency and low-intensity ultrasound to drive nano gas vesicles to achieve precision and reversibility.
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Interview with Professor Dong Qiang: The background and significance of the release of "Shanghai Expert Recommendations for the Management of Blood Pressure Variability in Inpatients with Ischemic Stroke"
Time of Update: 2021-10-11
Guide to September 26, 2021, led by Shanghai Stroke Society, led by Professor Dong Qiang from Huashan Hospital Affiliated to Fudan University, and written by Professor Zhao Yuwu from the Sixth People
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JAMA: Cerebral infarction is treated with endovascular treatment, should it be combined with alteplase?
Time of Update: 2021-10-11
Only for medical professionals to read and refer to clinical information, 1s to reach more cutting-edge clinical information, follow the clinical pharmacy channel to obtain the source of this article
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The American Heart Association recommends a diet that can promote a healthy brain. How to eat it?
Time of Update: 2021-10-11
More and more studies have found that following the brain-healthy diet (MIND diet) helps to improve cognitive function, delays the speed of brain aging, and is associated with a reduction in the risk of dementia such as Alzheimer's disease .
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Analysis of exosomal microRNA expression profile in urine of AMEM Alzheimer's disease 5XFAD mouse model
Time of Update: 2021-10-11
In this paper, a 1-month-old 5XFAD mouse model and its littermate control group in the early stage of Aβ plaque formation were selected to collect exosomes in urine and analyze the differential expression of miRNAs in them, using bioinformatics methods to analyze the differences The expressed genes were displayed, and at the same time, KEGG pathway analysis and GO enrichment analysis were performed on the differentially expressed genes screened out .
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Professor Cheng Xin: Can CTP predict the prognosis of acute lacunar infarction?
Time of Update: 2021-10-11
At the 24th National Conference on Neurology (NCN) of the Chinese Medical Association, Professor Cheng Xin from the Department of Neurology, Huashan Hospital Affiliated to Fudan University, asked "Can CTP predict the prognosis of acute lacunar infarction?" 》A wonderful report!
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Significantly alleviate the rate of progression of DMD disease, cell therapy reached the primary endpoint, Yi Mai Meng broke the news
Time of Update: 2021-10-11
Recommended reading: Sarepta/Roche's DMD gene therapy shows positive clinical resultsMedMeng broke the news in March 2021, at the MDA virtual clinical and scientific conference, Solid announced the latest clinical research results for Duchenne muscular dystrophy (DMD) .
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Professor Wang Huali: "Three-pronged approach", scientifically standardize the identification and treatment of Alzheimer's disease
Time of Update: 2021-10-11
*Only for medical professionals to read for reference. Early diagnosis and early treatment, win at the starting line! Expert profile Professor Wang Huali, Peking University Institute of Mental Healt
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Express GABA receptor allosteric modulator is eligible for priority review, significantly reducing the frequency of seizures
Time of Update: 2021-10-11
S. FDA has granted priority review status for its new drug application (NDA) for its GABAA receptor positivity modulator, ganaxolone, to treat epileptic seizures related to CDKL5 deficiency (CDD) .
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Today, it is reported that WuXi Junuo BCMA targeting CAR-T product has been approved for clinical use; magnetic thermal nanotechnology non-invasive treatment of Parkinson's...
Time of Update: 2021-10-11
Introduction: WuXi Giant Nuo BCMA targeted CAR-T product was approved for clinical use; the latest research shows that eating vegetables after eating farts is an important indicator of good health; magnetic thermal nanotechnology non-invasive treatment of Parkinson; Yinuo Pharmaceutical completed thousands Million USD in Series B financing.
