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Annals of Neurology: High-sensitivity cardiac troponin, which can predict future adverse vascular events
Time of Update: 2021-10-20
Patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA) are at high risk of recurrent vascular events . Some clinical prediction schemes, such as "age, blood pressure, clinical c
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Alzheimer's & Dementia: Air Pollution and Cognitive Impairment May Have Little Relationship: A Population-Based Cohort Study of Aging
Time of Update: 2021-10-20
Signs of recent decline in neurotoxicity of air pollution components in human populations and rodent models of blood vessels Recent signs of decline in neurotoxicity of air pollution components in human populations and rodent modelsIn the results of the US-wide Health and Retirement Study (HRS), the cognitive deficits of the less-educated cohort in 2004 were strongly associated with air pollution: among adults 65 years of age and older, PM2.
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How to recognize early cerebral infarction by head CT?
Time of Update: 2021-10-20
The following signs on plain CT can indicate cerebral infarction: cerebral artery high density sign; lenticular nucleus fuzzy sign; insular zone sign; brain parenchymal low density and local brain swelling sign .
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JNNP: Factors affecting the early prognosis of patients with impulsive and compulsive behaviors treated by deep brain stimulation of the subthalamic nucleus
Time of Update: 2021-10-20
According to the guidance program of the International Parkinson's Disease and Movement Disorders Society, patients are screened for DBS treatment, and patients are required to have sufficient levodopa responsiveness (Unified Parkinson's Disease Rating Scale III, UPDRS score improvement>30%).
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Front Neurol: Comprehensive bioinformatics analysis of potential mRNA and miRNA regulatory network in mice with ischemic stroke treated by electroacupuncture
Time of Update: 2021-10-20
However, the systematic analysis of new key genes, miRNAs and miRNA-mRNA networks regulated by EA in ischemic stroke is still lacking .
Finally, a comprehensive analysis of the results determined that miR-425-5p-Cdk1, mmu-miR-1186b-Prc1, mmu-miR-434-3p-Prc1 and mmu-miR-453-Prc1 miRNA-mRNA networks are key networks regulated by EA And is related to ischemic stroke .
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Stroke: ADC coefficient gradient, what is the significance after thrombectomy?
Time of Update: 2021-10-20
In this way, Dong-Seok Gwak and others of Kyungpook National University Hospital explored whether the pre-specified ADC520/ADC620 or ADC540/ADC620 ratio can predict good results for patients with large baseline ischemic lesions and successful recanalization through EVT .
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Nat Aging: APOE allele affects neuroinflammatory status in patients with Alzheimer's disease
Time of Update: 2021-10-20
Therefore, this study comprehensively shows that the A POEε4 allele may cause microglia to enter a phagocytic and pro-inflammatory state during normal aging and Alzheimer's disease through the APOE-TREM2-TYROBP axis .
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TAND: The relationship between blood glucose variability and clinical outcomes in patients with acute stroke
Time of Update: 2021-10-20
Poor functional outcomes in patients with ischemic stroke are relatedMethods: Continuous diabetic and non-diabetic, acute ischemic or hemorrhagic stroke patients received routine standard care finger prick measurement and continuous blood glucose monitoring (CGM) for up to 96 hours .
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Neurology: Migraine is obviously related to lipoprotein subcomponents
Time of Update: 2021-10-20
Therefore, Yanjun Guo and others of Harvard University used the data of the Women’s Genome Health Study (WGHS) to assess the phenotypic relationship between migraine and lipoprotein subcomponents, and used the large-scale international headache genetics consortium (IHGC).
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Clin Nutr: Zheng Liangrong's team from the First Affiliated Hospital of Zhejiang University found that high dimensional C levels can reduce the risk of cardiogenic stroke and Alzheimer's disease!
Time of Update: 2021-10-20
Heart blood vesselsZheng Liangrong, director of the Department of Cardiology, Zhejiang University First Affiliated Hospital, led his team to conduct a Mendelian randomized (MR) study to explore the relationship between vitamin C and 9 cardiovascular diseases (coronary artery disease [CAD], myocardial infarction [MI], atrial fibrillation) [AF], heart failure [HF], stroke , ischemic stroke [IS] and IS subtypes) and the causality of Alzheimer’s disease risk .
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JAD: At this stage before dementia, cognition may be improved by simply supplementing vitamin B!
Time of Update: 2021-10-20
PON1 gene product, also called serum paraoxonase, not only play an important role in detoxification organophosphorus nerve agents, but also of atherosclerosis , coronary heart disease and type 2 diabetes, or even nervous system disorders (including Alzheimer's disease) , etc.
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Stroke: Stroke patients, the core infarct area increases rapidly, and they benefit more from endovascular treatment
Time of Update: 2021-10-20
Several clinical trials published in 2015 showed that for patients within 6 hours of the onset of stroke, EVT is better than simple Intravenous thrombolysis (IVT) .
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Nat Aging: Real-world evidence supports the use of bumetanide in the treatment of APOE4-related Alzheimer's disease
Time of Update: 2021-10-20
The transcriptome of the AD characteristic of these mouse specific cell types was able to reverse the stem cellsFurthermore, in humans, bumetanide exposure is associated with a significant reduction in the prevalence of AD among individuals over 65 years old in two electronic health record databases, indicating the effectiveness of bumetanide in preventing AD .
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5 tables to master: the clinical application of 48 kinds of drugs for insomnia, anxiety and depression
Time of Update: 2021-10-20
in this class of drugs have a better effect on patients with insomnia and anxiety, and can reduce the frequency of night awakening, but Can significantly reduce slow-wave sleep, leading to a decline in recovery after sleep .
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Stroke: The relationship between HDL subtypes and occult cerebral infarction and ischemic stroke
Time of Update: 2021-10-20
HDL (High-Density Lipoprotein) Subspecies, Prevalent Covert Brain Infarcts, and Incident Overt Ischemic Stroke: Cardiovascular Health Study .
034299HDL (High-Density Lipoprotein) Subspecies , Prevalent Covert Brain Infarcts, and Incident Overt Ischemic Stroke: Cardiovascular Health Study in this message
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Neurology: Screening 3000 papers, what are the common neurological symptoms after the new crown
Time of Update: 2021-10-20
epilepsyIn this way, Shubham Misra and others of the All India Institute of Medical Sciences in India conducted a systematic review and meta-analysis to obtain aggregate prevalence estimates and understand the various neurological manifestations of COVID-19 patients in different age groups ( Including symptoms and diagnosis ) report frequency changes .
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Chinese Structural Week 2021 Ge Junbo: A Brief History of Transcatheter Treatment of Structural Heart Disease in China
Time of Update: 2021-10-20
Structural heart disease (SHD) of intervention in recent years, cardiac vascular interventional diagnosis and treatment of the most rapid development of the field . With the continuous development an
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Nature Genetics: Does stress make cancer cells stronger?
Time of Update: 2021-10-20
Research pattern diagramResearch Mode Diagram Research Mode DiagramThe researchers combined these in vivo analyses with in vitro perturbations to identify gene regulatory regions most susceptible to random DNA methylation changes, epigenetic regulation of transcription networks involved in glioma cell recognition, and DNA methylation disorders The cellular stress response that may be promoted .
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ENVIRON HEALTH PERSP: Common chemicals in electronics and baby products can impair brain development
Time of Update: 2021-10-20
. Reference materials:Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers, Environmental Health Perspectives (2021).
1289/EHP9285Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers, Environmental Health Perspectives (2021).
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Hypertension: Association between age at diagnosis of hypertension, brain structure and dementia
Time of Update: 2021-10-20
Diagnosis of hypertension in youth or middle age, but not in old age, is associated with a smaller brain volume and an increased risk of dementia .
