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JNNP: Tracking the clinical progression of posterior cortical atrophy, implications for diagnosis and post-treatment interventions
Time of Update: 2022-03-05
Diagnosis The current study aimed to (1) describe patterns of cognitive decline in PCA over time; and (2) evaluate the potential of a well-validated screening tool to monitor short- and long-term cognitive changes in both clinical and research settings .
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Alzheimers Dementia: New discovery of neurofilament light chain: Differentiate between mental illness and dementia
Time of Update: 2022-03-05
Secondary objectives included assessing the diagnostic utility of NfL and t-tau in differentiating ND, PSY, CJD/RapidND groups, and specific diagnoses within these groups .
Secondary objectives included assessing the diagnostic utility of NfL and t-tau in differentiating ND, PSY, CJD/RapidND groups, and specific diagnoses within these groups .
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Nature Medicine: Miracle!
Time of Update: 2022-03-05
As early as 30 years ago, preclinical and clinical studies have shown that epidural electrical stimulation (ESS) on the lumbosacral spinal cord can restore walking ability in patients with spinal cord
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Neurology: AAN Member Annual Salary Survey: Gender Salary Gap Exists Among Neurologists!
Time of Update: 2022-03-05
Researchers analyzed data from the 2019 Salary and Productivity Survey to assess the impact of gender on neurologist pay, testing the hypothesis that female neurologists will be paid less than male neurologists .
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Annals of Neurology: Parkinson's, regular aerobic exercise improves cognitive function
Time of Update: 2022-03-05
The significance of this study lies in the discovery that aerobic exercise stabilizes disease progression in the sensorimotor network of cortical brain regions and improves cognitive performance .
Aerobic exercise stabilizes disease progression in the sensorimotor network of cortical brain regions and improves cognitive performance .
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Neurology: bilateral symmetrical middle cerebellar peduncle infarction
Time of Update: 2022-03-05
Progressive fatigue and dysarthria for weeksBrain MRI showed a symmetrical middle cerebellar peduncle (MCP) infarction (Panels A, B, E) .
Teaching NeuroImage: Bilateral Middle Cerebellar Peduncle Stroke in Giant Cell Arteritis.
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Neuron: Heavy!
Time of Update: 2022-03-05
In this paper, it was found that the immune response can activate NPY neurons in the SrG-CG region to specifically regulate immune cells in the spleen to play an immunoregulatory role through splenic nerve branches.
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Stroke: Stroke patients, family members at increased risk of death
Time of Update: 2022-03-05
Age, stroke severity, female gender, cancer, coronary heart disease, diabetes, chronic obstructive pulmonary disease (COPD), high cholesterol, anemia, homocysteinemia, and elevated serum creatineCurrently, no studies have assessed the familial prognosis of IS .
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Annals of Neurology: Subcortical volume predicts fatigue-prone states in multiple sclerosis
Time of Update: 2022-03-05
This study revealed a predictive association of specific subcortical gray matter volumes with fatigue in an early and initially untreated multiple sclerosis cohort .
Predictive association of specific subcortical gray matter volumes with fatigue in an early and initially untreated multiple sclerosis cohort Original source: Fleischer V, Ciolac D, Gonzalez‐Escamilla G, et al.
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Alzheimers Dementia: Lower systolic blood pressure lowers dementia risk later in life
Time of Update: 2022-03-05
Kuller et al hypothesized that lower untreated systolic blood pressure (SBP) is associated with a lower risk of dementia and death until age 95 .
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Alzheimers Dementia: The more stable BMI, the less likely cognitive decline
Time of Update: 2022-03-05
12525) Stability in BMI over time is associated with a better cognitive trajectory in older adults.
12525) Stability in BMI over time is associated with a better cognitive trajectory in older adults.
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Stroke: Endovascular therapy, is there a difference between black and white Americans?
Time of Update: 2022-03-05
In a previous study examining selected hospital subgroups, black patients were less likely to receive intravenous recombinant tissue-type plasma protein activator (IV tPA) and EVT compared with white patients .
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Alz Res Therapy: Novel Single-Cell Marker Predicts Changes in Cognitive Function
Time of Update: 2022-03-05
The significance of the study lies in its finding that at 4 years of follow-up, baseline plasma MCP-1 levels were associated with longitudinal decline in overall cognitive and representational memory performance in older adults .
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Annals of Neurology: Spinal cord atrophy predicts progression in relapsing multiple sclerosis
Time of Update: 2022-03-05
The definition of asymptomatic progression used here arises from the assumption that there is clinically asymptomatic neurodegeneration (measurable as CNS atrophy on MRI) that precedes and predicts relapse-free EDSS worsening in a certain In some cases a course of SPMS eventually develops, and this neurodegeneration occurs in patients with and without relapses .
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Stroke: New findings from Tiantan Hospital: U-shaped high-density lipoprotein cholesterol and stroke risk
Time of Update: 2022-03-05
The significance of this study is its finding that both low and high cumulative mean HDL-C were associated with increased risk of ischemic and hemorrhagic stroke .
Both low and high cumulative mean HDL-C were associated with an increased risk of ischemic and hemorrhagic stroke .
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This article summarizes 5 common complications after thrombolysis and their management
Time of Update: 2022-03-05
The "Chinese Guidelines for Endovascular Treatment of Acute Ischemic Stroke 2018" proposed that thrombolysis combined with antiplatelet therapy may reduce the occurrence of reocclusion [2] .
The "Chinese Guidelines for Endovascular Treatment of Acute Ischemic Stroke 2018" proposed that thrombolysis combined with antiplatelet therapy may reduce the occurrence of reocclusion [2] .
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NICE|The guidelines for diagnosis and treatment of headaches are updated after 10 years!
Time of Update: 2022-03-05
Treatment with a combination of oral triptans and NSAIDs or oral triptans and acetaminophen should take into account the individual patient's circumstances, the risk of complications and adverse events .
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Movement disorders: Neuroimaging findings: Parkinson's patients, cholinergic innervation is altered
Time of Update: 2022-03-04
Mild cognitive impairment (PD-MCI) is already present in 25% to 30% of newly diagnosed patients and is a major risk factor for the development of PD dementia (PDD) .
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Annals of Neurology: What systems are mainly involved in acute sequelae after COVID-19?
Time of Update: 2022-03-04
Postural orthostatic tachycardia syndrome (POTS) is characterized by symptoms similar to PASC, including chronic fatigue, orthostatic intolerance, and brain fog associated with decreased orthostatic cerebral blood flow and dysautonomia .
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AJNR: Abnormal tongue signal on emergency MRI for the diagnosis of seizures
Time of Update: 2022-03-04
On brain magnetic resonance imaging, we observed tongue signal abnormality (TSA), which was subsequently shown to be associated with tongue bite, a sign supporting the diagnosis of unrecognized seizures .