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Recognition of CP cerebral palsy disease (CP mimic)
Time of Update: 2022-03-07
Author: darkpigx Source: "I can still eat a small fish and worm" Public account Definition of cerebral palsy Cerebral palsy (cerebral palsy, CP) referred to as cerebral palsy, is a group of non-progressive brain damage caused by the developing fetus or infant A syndrome of persistent, developmental motor and postural disorders, resulting in limited mobility; often with sensory, perceptual, cognitive, communication, and behavioral impairments, as well as epilepsy and secondary musculoskeletal problems .
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Is direct thrombectomy effective for large cerebral infarction within 24 hours of onset?
Time of Update: 2022-03-07
Figure 1 Study title RESCUE-Japan LIMIT Study Description This is a multicenter, randomized clinical trial conducted by Japanese researchers, which included 203 patients with baseline ASPECTS 3-5 (scores range from 0 to 10, lower 101 patients were randomly assigned to endovascular therapy and 102 patients were randomly assigned to The medical-care group .
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Management of tardive dyskinesia, have you mastered all these issues?
Time of Update: 2022-03-07
Because TD occurs most often in patients receiving long-term antidopaminergic medication, clinicians should use the lowest effective dose for the shortest possible treatment time .
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Biohaven and Bioshin's Pivotal Trial of rimegepant (NURTEC® ODT) for Acute Treatment of Migraine Hits Primary Endpoint Press Release
Time of Update: 2022-03-07
- is the first oral calcitonin gene-related peptide NURTEC® ODT (CGRP) receptor antagonist to show positive results in a pivotal trial in Asia Pacific, with more than 100 million patients suffering from migraine in China and South Korea alone .
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Dementia before getting old?
Time of Update: 2022-03-07
Therefore, synchronizing with the circadian rhythm is essential for good health, and staying up late, sleep deprivation or sleep disturbance can cause the body's circadian rhythm to be disturbed, so that the daily "night shift" of the immune cells responsible for clearing the accumulated waste in the brain throughout the day works time decrease, causing Aβ to start accumulating in the brain .
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Chinese scholars prove that water sports can effectively reduce low back pain
Time of Update: 2022-03-07
On a 10-point pain scale, patients in the water exercise group showed nearly 2 points greater improvement than those in the conventional physical therapy group .
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Prof. Xiaochun Chen: 2021 Alzheimer's Disease Research Memorabilia
Time of Update: 2022-03-07
"Medical Neurology Channel" specially invited Professor Chen Xiaochun from Union Hospital Affiliated to Fujian Medical University to share, mainly including pathogenic genes and related mechanisms, Let's take a look at the four aspects of classification diagnosis, risk prediction, and treatment progress~1AD new causative gene discovered Genome-wide association studies (GWAS) have identified many risk loci for AD, but how do these loci lead to AD risk It's not clear .
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Science︱Breakthrough!
Time of Update: 2022-03-06
Major vascular cell types were identified: endothelial cells (CLDN5), pericytes (KCNJ8), SMCs (MYH11), and perivascular fibroblasts (DCN) (Fig.
To determine molecular changes in endothelial and perivascular cells in AVMs, the authors identified differentially expressed genes in control and AVMs (Fig.
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This NIHSS score is very knowledgeable!
Time of Update: 2022-03-06
For example, with neglect due to damage to the right side of the brain, the patient will be unable to pay attention to, or be unresponsive to, stimuli on the left side .
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How much does it help the brain to keep exercising for 5 years?
Time of Update: 2022-03-06
Effects of 5 Years Aerobic Exercise on Cognition in Older Adults: The Generation 100 Study: A Randomized Controlled Trial.
5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did.
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Cell Metab "islet-lowering, blood sugar-lowering" hypothalamus and islet β-cell transneural circuit connections
Time of Update: 2022-03-06
It has been found that glucose-sensing neurons, mainly located in the hypothalamus, respond to hyperglycemia or hypoglycemia [1] and can regulate insulin secretion, but the neuroanatomy and function of specific neuronal populations in the brain and pancreatic beta cells Intercellular communication remains unknown .
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Alteplase vs. Tenecteplase: How Does Symptomatic Intracranial Hemorrhage Occur?
Time of Update: 2022-03-06
Steven Warach from The University of Texas at Austin presented their study[1]—in acute stroke treatment, after routine tenecteplase and alteplase intravenous thrombolysis, the incidence of sICH .
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Cell Metabolism: Neural Circuits for Fibroblast Growth Factor 21 Restriction of Alcohol Use
Time of Update: 2022-03-06
Potthoff of the University of Iowa revealed that the increase of FGF21 caused by alcohol use is mainly produced by the liver, and FGF21 can specifically act on the projection of KLB-positive neurons in the BLA brain region to the nucleus accumbens.
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Inexplicable intracranial lesions, the director shared the diagnosis process, it was wonderful!
Time of Update: 2022-03-06
1) showed bilateral frontal and parietal lobes with symmetrical large hypodensity; blood routine and liver function were generally normal, and no relevant treatment was performed .
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"Science" breakthrough: New research brings new understanding of such diseases that only affect the human brain
Time of Update: 2022-03-06
▲Schematic diagram of the research method (Image source: Reference [1]) The researchers obtained cells from several patients with tuberous sclerosis complex with TSC2 mutations, and cultured human brain organoids to analyze the development process of the patient’s brain Molecular and cellular mechanisms at specific moments in "With this approach, we found that organoids can grow tumor-like in patients' brains, with disorganized nodule-like structures , " describe the study authors .
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Wang Liping's team assesses the impact of development and evolution on sequential learning and memory
Time of Update: 2022-03-06
Through behavioral analysis and modeling, the study found that when adults, children and macaques completed the same spatial sequence task, there were not only differences in the accuracy of information encoding, but also differences in the processing methods of relational structures .
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How to deal with orthostatic hypotension caused by PD?
Time of Update: 2022-03-06
Table 1 ➤Treatment of OH ➤Treatment of OH has 4 goals: to improve OH without increasing supine blood pressure; to prolong the time that patients stand; to relieve symptoms of OH; to improve the ability of patients with OH to perform daily upright activities .
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Check it out!
Time of Update: 2022-03-06
On February 3, 2022, the research team of Nicolas Renier of the Brain Institute of the Sorbonne University in Paris revealed the key neuron group that regulates the adaptive behavior (nesting behavior) of pregnant mice: the CART-positive neuron group in the EA area, which inhibits this type of neuron group After inhibiting nesting behavior, activate the neuron to promote nesting behavior .
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Stroke caused by giant cell arteritis - how much do you know about such imaging findings?
Time of Update: 2022-03-06
Figure 2 Whole body 18FDG-PET/CTAA and B showing increased grade 3 mural uptake at bilateral subclavian (A) and common carotid (B) levels (grade 3 is considered consistent with vasculitis according to a review by Nielsen et al.
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Important progress in understanding Alzheimer's disease!
Time of Update: 2022-03-06
News from the research institute states that this study provides the first high-resolution structure of Aβ42 protein fibrils derived from human brain tissue .
