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Stroke: Small lesions are big problems. The elderly have "white matter lesions" in physical examination. How to take medicine to delay the process?
Time of Update: 2022-04-22
To compare the effects of cilostazol and aspirin on changes in WMC volume in patients with cerebral small vessel disease, scientists from South Korea conducted a related study and published the results in the journal Stroke .
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Stroke: After stroke, the lower the damage to the infarct core, the greater the benefit after perfusion
Time of Update: 2022-04-22
The significance of this study lies in the finding that, in patients with ischemic stroke, a reduction in the severity of intra-infarct tissue damage, as determined by assessing BBB integrity, is independently associated with improved functional outcomes .
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Technical considerations and application scenarios for a novel thrombectomy technique (SPACEMAN): a prospective study
Time of Update: 2022-04-22
55;strokeIn terms of age, sex, vascular risk ( hypertension , diabetes , hyperlipidemia, atrial fibrillation, coronary heart disease, ischemic stroke, and smoking), NIHSS at admission, DWI-ASPECTS score, intravenous thrombolysis or general vascular occlusion, No significant difference between groups;high blood pressure diabetesThe time from symptom onset to puncture, salvage endovascular therapy (balloon angioplasty and/or stenting) and embolization rates were also similar between the ICAS groups;No technique-related complications or embolism occurred in the SPACEMAN group .
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JNNP: Impact of the COVID-19 pandemic on treatment options for multiple sclerosis in the UK
Time of Update: 2022-04-22
Natalizumab is the only high-potency monoclonal antibody therapy recommended as “safe” during COVID-19 , the starting number increased by 46.
Recently, the trend of increasing the number of DMT treatments has reversed, with the largest decrease in the number of highly potent monoclonal antibody therapies .
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JNNP: Regulation of exercise environment on spike activity in the substantia nigra reticularis in patients with Parkinson's disease
Time of Update: 2022-04-22
These behavioral differences were associated with increased responsiveness of SNr neurons, that is, greater changes in activity compared to baseline in a patterned environment.
This study examined whether signal-to-noise activity in Parkinson's disease patients is associated with changes in motor performance mediated by different environments .
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Alzheimers Dementia: Improving air quality may help prevent dementia
Time of Update: 2022-04-22
At the same time, some epidemiological studies have found a positive correlation between exposure to air pollution and the risk of dementia in different geographic settings and populations .
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Neurology: Early MRI features of children with tuberous sclerosis (TSC) are significantly correlated with secondary epilepsy and neurodevelopmental outcomes before age 2!
Time of Update: 2022-04-22
Brain lesions are one of the hallmarks of the disease and can be found in more than 90% of patients and include nodular or cortical dysplasia, white matter abnormalities such as radial transition lines, subependymal nodules, and subependymal giant cells Astrocytoma.
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JNNP: Comparison of ecuazumab and rituximab in the treatment of generalized myasthenia gravis
Time of Update: 2022-04-22
Therefore, in a retrospective observational study, the efficacy of rituximab and ecuadorizumab for the treatment of systemic, refractory anti-AChR antibody-positive MG was compared .
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JNNP: Multimodal prognostic features of seizures in epilepsy surgery
Time of Update: 2022-04-22
Quality of life prognostic features may be related to patient characteristics (eg, age, seizure characteristics, variability of seizures, and genetics), findings (focal lesions on MRI and localization of epileptic activity on EEG), surgical factors (resection margins or technique) and a combination of the above factors (concordance between imaging and neurophysiology) .
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Stroke: Efficacy of endovascular thrombectomy in children with acute ischemic stroke
Time of Update: 2022-04-22
CONCLUSIONS : A cross-sectional assessment of the clinical course and short-term outcomes of pediatric patients with ischemic stroke treated with EVT suggests that EVT may be a safe modality with high favorable functional outcomes .
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HBM: Structural MRI-Based Brain Features to Differentiate MCI, PMCI, and AD
Time of Update: 2022-04-22
Changes in individual networks can help identify people who progress from MCI to AD, and understanding these changes throughout the transition may help delay the transition from MCI to AD Structural MRI (sMRI) can be used to detect brain atrophy for understanding Alzheimer's disease Neurodegenerative diseases such as Alzheimer's disease (AD) provide valuable information .
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Alzheimers Dementia: Alzheimer's Disease: Synaptic Density and Cognitive Function
Time of Update: 2022-04-22
A subsequent clinicopathological investigation involving individuals with mild cognitive impairment (MCI) and focusing on the hippocampus demonstrated that the number of synapses in the dentate gyrus (outer molecular layer) correlates with cognitive performance before death, In a pooled sample, patients with advanced dementia and normal controls were included .
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Lancet sub-issue my country Air Force Military Medical University: Don't underestimate enteral nutrition, it can affect the prognosis of stroke!
Time of Update: 2022-04-22
references:Safety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
1016/S1474-4422(22 )00010-2Safety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
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Neurology: A special case of AMAN
Time of Update: 2022-04-22
Hypothyroidism and dyslipidemia, and treat accordingly with levothyroxine and rosuvastatinPhysical examination revealed normal muscle strength, sensation, deep tendon reflexes, and coordination in the upper and left leg .
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Crit Care: Accuracy of Heparin Binding Protein in Diagnosing Nosocomial Meningitis and Ventriculitis
Time of Update: 2022-04-22
diagnosisRecently, a research article was published in Critical Care, an authoritative journal in the field of critical care medicine, to investigate the effect of cerebrospinal fluid heparin-binding protein (HBP) compared with procalcitonin and lactate in hospital-acquired meningitis and ventriculitis.
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Biomed Res Int: Acupuncture for Parkinson's disease with sleep disturbance and dose-response
Time of Update: 2022-04-22
ActiGraph showed that the sleep efficiency on day 6 of sham operation and acupuncture treatment was significantly lower than that on day 5 (P<0.
The sleep efficiency on the 5th, 6th and 7th day in the acupuncture treatment group was significantly higher than that in the sham acupuncture group (P<0.
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One picture to understand: Postherpetic nerve pain
Time of Update: 2022-04-22
Diagnosis of postherpetic neuralgiaPostherpetic Nerve Pain Diagnosis Ideas Postherpetic Nerve Pain Diagnosis IdeasA medical history inquiry1.
Inquiry of medical history 1.
Physical examination 2.
Physical examination 2.
Laboratory examination 3.
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Alzheimers Dement: Different races have different long-term trends in Alzheimer's-related indicators
Time of Update: 2022-04-22
, University of Washington, assessed longitudinal differences between blacks and whites in all major AD biomarkers, including CSF, amyloid PET, and structural MRI .
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Neurology: Cerebral microbleeds, cerebral amyloid angiopathy and their relationship to quantitative markers of neurodegeneration
Time of Update: 2022-04-22
Dilated perivascular space (PVS) Here, we sought to elucidate how CMBS correlates with morphological changes in the brain (supratentorial brain volume, gray and white matter volumes, and cortical thickness), as well as other hallmarks of small vessel disease .
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Professor Xu Yahui in the expert lecture hall: A study on the efficacy and safety of four antidepressants in the treatment of chronic insomnia
Time of Update: 2022-04-22
Xu Yahui, Second Affiliated Hospital of Xinxiang Medical CollegeThe Second Affiliated Hospital of Xinxiang Medical College Xu Yahui The Second Affiliated Hospital of Xinxiang Medical College Xu YahuiPurposepurpose purposeTo explore the effects of four antidepressants on sleep quality, daytime fatigue and sleepiness, anxiety and depression symptoms, blood pressure, blood sugar, and electrocardiogram in patients with chronic insomnia, in order to clarify the efficacy and safety of the four drugs in the treatment of chronic insomnia .
