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Alzheimers Dementia: What does daytime naps have to do with dementia?
Time of Update: 2022-04-23
Longer and more frequent daytime naps are associated with a higher risk of Alzheimer's dementia .
The significance of the study lies in the discovery that excessive daytime naps and Alzheimer's disease may have a bidirectional relationship, or share a common pathophysiological mechanism .
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Neurology: Novel tPA tenecteplase is safer and more effective for stroke patients with large artery occlusion!
Time of Update: 2022-04-23
Among patients ≤80 years of age, there were no differences in 90-day mRS, mortality, or symptomatic ICH between TNK 0.
0000000000013302Safety and Efficacy of Tenecteplase in Older Patients With Large Vessel Occlusion A Pooled Analysis of the EXTEND-IA TNK Trials.
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Alzheimer's & Dementia: Regions with low socioeconomic status have high rates of missed and delayed diagnosis of dementia
Time of Update: 2022-04-23
A higher proportion of residents over the age of 65 was associated with a lower age-adjusted dementia incidence (OR 0.
Age-adjusted incidence of dementia diagnosis was lower in cities with low nSES levels .
Age-adjusted incidence of dementia diagnosis was lower in cities with low nSES nSES levels .
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npj Parkinsons Dis: Metabolite and lipid studies revealing oxidative stress status in emerging Parkinson's disease
Time of Update: 2022-04-23
Metabolomics has become a powerful tool to characterize the biochemical characteristics of the pathogenesis of different diseases and provides useful applications in the biomedical field .
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Stroke: Differences in outcomes of different shunt modes in the treatment of symptomatic carotid stenosis with carotid endarterectomy
Time of Update: 2022-04-23
To assess the impact of surgeons' shunt practices and shunt use on early outcomes of carotid endarterectomy (CEA) in recent symptomatic patients, experts from the Mayo Clinic Cerebrovascular Surgery conducted a study published in the journal Stroke on .
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HUMAN BRAIN MAPPING: Partial recovery of truncated posterior frontal-limbic neural circuits in heroin addicts
Time of Update: 2022-04-23
Compared with baseline (HU1), HU2 showed improved cognition (shorter time to TMT-A), decreased craving, and significantly higher cortical thickness in the bilateral superior frontal gyrus (SFG) at HU2 than at HU1 .
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HUMAN BRIAN MAPPING: Brain Morphological Indicator Predicts Severity of Internet Excessive Use
Time of Update: 2022-04-23
The study found that, in addition to the reward system, morphological indicators of the brain, including the left precentral gyrus (curvature), the left superior temporal gyrus (surface area), the right cuneiform (folded index), and the right anterior cingulate coracoid (folded) index), which can predict the severity of EIU, indicating widespread changes in the brain .
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Stroke: The effect of deferoxamine treatment on the trajectory of intracerebral hemorrhage
Time of Update: 2022-04-23
Longitudinal trends in modified Rankin Scale scores at prespecified time points from day 7 to the end of the 6-month follow-up period in a trial of patients with intracerebral hemorrhage treated with deferoxamine (i-DEF trial) .
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JPD: What factors affect the long-term quality of life in the treatment of Parkinson's disease with levodopa-carbidopa intestinal gel?
Time of Update: 2022-04-23
Numerous studies have shown that LCIG can improve motor and nonmotor fluctuations, dyskinesia, and health-related quality of life (HRQoL) in patients with advanced PD .
Improvements in HRQoL after 12 months of treatment with LCIG were moderately positively correlated with improvements in non-motor symptoms (PCC=0.
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JAMA Net Open: Offspring with concurrent exposure to preeclampsia, perinatal complications, neurodevelopmental disorders, high risk of psychiatric disorders
Time of Update: 2022-04-23
26) After exposure, offspring exposed to preeclampsia and perinatal complications are at increased risk of developing any neurodevelopmental or psychiatric disorders .
This cohort study found that offspring exposed to maternal preeclampsia and perinatal complications had a slightly increased risk of developing intellectual disability, specific developmental disorders, ADHD and conduct disorders, and other behavioral and emotional disorders .
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Alzheimers Dementia: What are the characteristics of brain metabolism in patients with delirium?
Time of Update: 2022-04-23
They used 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) to assess brain glucose metabolism in elderly patients with and without delirium, all without clinical dementia (N = 20) .
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Alzheimers Dementia: What are the specific characteristics of cognitive impairment in a survey of 5,000 people in rural China?
Time of Update: 2022-04-23
Furthermore, most epidemiological studies in China use only simple cognitive screening tests to define MCI, such as the Mini Mental Status Examination (MMSE) and Montreal Cognitive Assessment (MoCA), with few combinations of standard neuropsychological tests was used to define MCI and subtypes of MCI .
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Alzheimers Dementia: What are the characteristics of dementia-related medical expenditures?
Time of Update: 2022-04-23
of the University of Pennsylvania estimated the incremental cost of ADRD to public finances in the first 5 years after diagnosis through Medicare (Parts A, B, and D) and Medicaid .
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npj Parkinsons Dis: neutrophil to lymphocyte ratio predicting survival in multiple system atrophy
Time of Update: 2022-04-23
In a multivariate Cox regression model, higher NLR increased the risk of death in MSA patients after adjusting for confounders (HR = 1.
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JPD: Parkinson's patients, how has long-term health care spending changed?
Time of Update: 2022-04-23
Using a longitudinally matched cohort study from 2008-2017 of linked data from the Parkinson's Disease and Movement Disorders and Medical Administrative Database of the National Institute of Neurosciences in Singapore, they compared patients and controls matched according to age, sex, ethnicity and Charlson Complications Index score Healthcare utilization and costs between groups .
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BMJ: Taking antidopaminergic antiemetics is associated with increased risk of ischemic stroke
Time of Update: 2022-04-23
We conducted a case-control study to identify ischemic stroke risk associated with antidopaminergic antiemetic (ADA) use .
We conducted a case-control study to identify ischemic stroke risk associated with antidopaminergic antiemetic (ADA) use .
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Alzheimers Dementia: Regular Tai Chi may improve cognitive decline
Time of Update: 2022-04-23
A meta-analysis study including 12 clinical trials found that Tai Chi exercise had a large beneficial effect on global cognitive ability and long-term delayed recall, as well as executive function .
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A typical case of spinal cord intramedullary teratoma combined with congenital spinal developmental malformation - a case of scoliosis
Time of Update: 2022-04-23
In recent years, we have tried to perform one-stage surgery in suitable cases to treat spinal cord intramedullary tumors and scoliosis at the same time, in order to reduce the increased risk of complications and economic burden caused by multiple surgeries .
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The first domestic dictionary-type anti-Paris reading book "Anti-Paris Dictionary" was released 25 experts in the field of Parkinson's disease participated in the editing and review
Time of Update: 2022-04-23
Professor Chen Shengdi from the Department of Neurology, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, the leader of the society, pointed out that there are about 3 million Parkinson's disease patients in China, and the incidence rate of middle-aged and elderly people over 65 years old is 1.
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Frontiers in Neuroscience: Abnormal cerebrovascular responses and functional connectivity due to white matter hyperintensity lead to cognitive decline
Time of Update: 2022-04-23
The study concluded and published a research article titled Abnormal Cerebrovascular Reactivity and Functional Connectivity Caused by White Matter Hyperintensity Contribute to Cognitive Decline in Frontiers in Neuroscience, which explores cerebrovascular reactivity (CVR ) severe WMH may lead to local CVR Decreases , which in turn lead to FC abnormalities, which ultimately lead to cognitive decline .
