-
Episodic blurred vision, in addition to cerebral infarction, do not miss this cause
Time of Update: 2022-05-31
Figure 3 Chest CT and head MRI enhanced scan According to the patient's symptoms, signs and auxiliary examinations, the bottom line was unraveled, and the diagnosis was: Horner syndrome; right upper lobe cancer (high probability) .
-
MRI clues for differential diagnosis of ataxia
Time of Update: 2022-05-31
Introduction Brain MRI scans are very helpful in differentiating the various forms of ataxia .
Table 1 MRI clues for differential diagnosis of sporadic and hereditary ataxias compiled from: Manto M, Habas C.
Cerebellar disorders: clinical/radiologic findings and modern imaging tools.
-
Review of Trends Neurosci︱Research progress on biological clock and circadian rhythm of blood glucose
Time of Update: 2022-05-31
On April 21, 2022, the team of Zheng Sun from Baylor College of Medicine published a review article titled "Circadian clock, diurnal glucose metabolic rhythm, and dawn phenomenon" in Trends in Neurosciences, summarizing the role of the central circadian clock in blood glucose metabolism day and night.
-
Aging Cell Review︱ Zhang Hong/Chen Yingzhi/Tian Mei collaborated to review the mechanism of gut microbiota regulating microglia function in cognitive aging
Time of Update: 2022-05-30
Written by ︱ Zhou Rui editor ︱ Wang Sizhen Aging is an inevitable life process that almost all living things have to go through . In recent years, with the improvement of living standards and the
-
Courier molecular glue cutting-edge once again reached a research and development cooperation, pointing to neurological diseases
Time of Update: 2022-05-30
▎WuXi AppTec Content Team Editor Today, Plexium announced that it has entered into a research and development agreement with AbbVie to jointly develop innovative targeted protein degradation therapies for neurological diseases .
-
Ruijian Pharmaceutical "Qingqi" received the first IND acceptance of pluripotent stem cell-derived drug in the field of Parkinson's disease in China
Time of Update: 2022-05-30
As the world's first high-tech pharmaceutical company focusing on the research of high-efficiency chemical small molecules to induce functional cell regeneration, Ruijian Medicine has established an induced pluripotent stem cell (iPSC) product development platform based on regenerative medicine .
-
Express FDA release, Pfizer DMD gene therapy phase 3 clinical trial is about to restart
Time of Update: 2022-05-30
S. Food and Drug Administration (FDA) has notified the company to allow its Phase 3 clinical trial of fordadistrogene movaparvovec, a gene therapy for Duchenne muscular dystrophy (DMD), to continue .
-
Nature: Major progress!
Time of Update: 2022-05-30
Studies have demonstrated the existence of neuroimmune-vascular junctions in the adventitial segments of atherosclerotic disease in mice and humans, as shown by the formation of growth cones near the axon terminals of immune cells and smooth muscle cells .
-
After a lapse of 6 years, Fujian Agriculture and Forestry University published Science as the first unit, revealing that the transiently activated dopamine signal in the bee brain regulates food desire
Time of Update: 2022-05-30
Recently, the research team of Fujian Agriculture and Forestry University Su Songkun led the team of Professor Martin Giurfa from the University of Toulouse III, France, and Professor Zhang Shaowu fr
-
"Science": Enterobacteria directly regulate host appetite and body temperature!
Time of Update: 2022-05-29
After entering the brain through blood circulation, the cell wall peptides secreted by enterobacteria interact with Nod2 expressed in hypothalamic neurons to inhibit the activity of neurons, thereby inhibiting the appetite of mice and regulating metabolic activities such as body temperature and body weight homeostasis .
-
Nature Aging Feng Jianfeng/Cheng Wei of Fudan University reveals that 7 hours of sleep every night is just right, too much or too little sleep can damage the brain and mental health
Time of Update: 2022-05-29
Data from the UK Biobank (nearly 500,000 people, mostly participants aged 38-73 of European ancestry, including 94% white), identified a non-linear association between sleep, with approximately 7 hours being the optimal sleep time (sleep Too much or too little sleep is associated with poorer cognitive performance and mental health), while genetic and cognitive factors, brain structure and mental health are key indicators .
-
Why do hugs, hands, and caresses make us feel so comfortable?
Time of Update: 2022-05-29
The Human Pleasant Touch Conditioned Place Preference (PT-CPP) test shows that genetic ablation of spinal excitatory interneurons expressing prokineticin receptor 2 (PROKR2) or its ligand PROK2 in sensory neurons abolishes PT-CPP , without impairing pain and itching behavior in mice .
-
The effect of high triglyceride on prognosis of stroke patients
Time of Update: 2022-05-29
For patients with stroke or transient ischemic attack (TIA), the focus of lipid management is mostly statin therapy for elevated low-density lipoprotein (LDL) .
Among patients with cardioembolic stroke, the incidence of MACE did not differ significantly by triglyceride level .
-
Antithrombotic therapy for patients with acute cerebral infarction/TIA, see what the latest guidelines say?
Time of Update: 2022-05-29
The author specially translates the key parts of it for peer reference, as follows: Introduction to the main international guidelines and the Korean Stroke Society (KSS) previous Clinical Practice Guidelines (CPG) recommended aspirin monotherapy as acute antithrombotic therapy .
-
Suntech's first launch of Suntech Pharmaceuticals completed hundreds of millions of yuan in Series C financing to promote the development of a new generation of brain disease treatment drugs
Time of Update: 2022-05-29
"Since the results of the clinical trial of the company's ACT001 drug in the treatment of DIPG (diffuse intrinsic pontine glioma in children) were presented in the form of a report at the SNO meeting in June 2021, we have received reports from around the world including Hong Kong, California and Utah.
-
Cell Res︱Li Dan/Wang Jian/Liu Cong collaborated to discover and characterize novel pathological protein fibril aggregates formed by TMEM106B in human brain
Time of Update: 2022-05-29
On April 27, 2022, Li Dan's research group from Shanghai Jiao Tong University, Wang Jian's research group from Huashan Hospital Affiliated to Fudan University, and Liu Cong's research group from Shanghai Institute of Organic Chemistry jointly published an online publication in Cell Research entitled "Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders" .
-
What are the characteristics of infarcts in different parts of the cerebellum?
Time of Update: 2022-05-29
Patients with infarcts in the AICA supply area mainly present with a combination of symptoms including dizziness/vertigo, nystagmus, hearing loss, loss of limb and facial sensation, ataxia, and dysmetria .
-
Review of Neural Regen Res︱Guo Junhong's team focuses on the interaction between β-amyloid and cerebral vascular endothelial cells in Alzheimer's disease
Time of Update: 2022-05-29
2. Cerebral vascular endothelial cells mediate Aβ transport and clearance Studies have shown that the blood-brain barrier plays an important role in the peripheral transport and clearance of Aβ[12] .
Blood-brain-barrier models for the investigation of transporter- and receptor-mediated amyloid-β clearance in Alzheimer's disease.
-
Science Review of "Collector's Edition"｜Memory regulation of the sleeping brain
Time of Update: 2022-05-29
Finally, the role of these EEG activity patterns in maintaining sleep homeostasis is emphasized, and future research issues and challenges for sleep involvement in memory-related learning consolidation are prospected .
SWR and cortical NREM sleep patterns are temporally coordinated, a mechanism thought to promote plasticity and long-term consolidation of scene (event) memory .
-
Nature: These immune cells are all over the brain, and their origin and function have just been discovered…
Time of Update: 2022-05-28
Using cutting-edge single-cell analysis techniques, cell fate tracking, and cell-specific transgenic mouse models, the researchers labelled different types of brain macrophages and their progenitors to confirm these Specialized macrophages and microglia distributed in the meninges, blood vessels, etc.
