-
Neuron Tsinghua University Xiao Bailong's team found that astrocyte Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive function
Time of Update: 2022-08-20
On August 12, 2022, Xiao Bailong's team from Tsinghua University published a research paper titled "Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions" online in Neuron, which demonstrated the exploration of mechanically gated Piezo1 channels in astrocytes It is expressed during the process and exploits its mechanosensitivity to mediate mechanically evoked Ca 2+ responses and ATP release, thereby establishing Piezo1-mediated mechanochemical transduction in astrocytes .
-
Research︱Chen Zhong's team reveals the circuit mechanism of lateral hypothalamic CaMKIIα+ neurons regulating predatory behavior
Time of Update: 2022-08-20
On August 9, 2022, the team of Professor Zhong Chen from the School of Pharmacy, Zhejiang University, and the research team from Zhejiang University of Traditional Chinese Medicine published an online publication titled "Lateral Hypothalamus Calcium/calmodulin-dependent protein kinase II α Neurons Encode Novelty-Seeking Signals to Promote "Predatory Eating" research paper, reports the latest research results of the circuit mechanism of the lateral hypothalamus (Lateral Hypothalamus, LH) mediated predation behavior in mice .
-
Can I still sleep in the afternoon?
Time of Update: 2022-08-20
*For medical professional reading reference onlySleep is very important to human health. People may spend one third of their life in sleep. In North America, the Middle East and China, naps are very c
-
Interview with Professor Yuan Junliang: Interpretation of Expert Consensus 2021 on the Management of Cognitive Impairment after Stroke CSA & TISC 2022
Time of Update: 2022-08-20
Post-stroke cognitive impairment (PSCI) is a common complication of stroke, which not only seriously affects the quality of life of patients, but also significantly reduces the survival time of stroke
-
Sci Transl Med Microglia Mediate Genetic Variation in Parkinson's Disease
Time of Update: 2022-08-20
To investigate which type of cell's LRRK2 gene expression mediates Parkinson's disease risk, researchers from the National Institutes of Health recently published a paper titled Association of a common genetic variant with Parkinson's disease is mediated online in Science Translational Medicine.
-
NEJM (IF=176) 2 articles!
Time of Update: 2022-08-20
In a 52-week, multi-center, double-blind, 2 In the Phase 1 trial, participants with early-stage Parkinson's disease were randomly assigned in a 2:1:2:2 ratio to receive either placebo (control) or an intravenous infusion of cinpanemab .
-
Regarding "hemorrhagic transformation in patients with intravenous thrombolysis", these three points should be clear
Time of Update: 2022-08-20
*For medical professional reading reference onlyHighlights of the 2022 Temple of Heaven FairThe key to the treatment of ischemic stroke is early reperfusion therapy. Intravenous administration of alte
-
BMC Med︱Zhou Cheng/Huang Han/Zhang Donghang team discovered a new mechanism of long-term cognitive impairment caused by neonatal sepsis
Time of Update: 2022-08-20
On July 27, 2022, researcher Zhou Cheng's research group from West China Hospital of Sichuan University published a paper entitled "Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development" in BMC Medicine research .
-
[The Lancet] Prophet: Blood test in new brain injury patient predicts death, severe disability!
Time of Update: 2022-08-20
This article is original from Translational Medicine Network, please indicate the source for reprinting Author: SophiaA blood test within 24 hours of a traumatic brain injury (TBI) can indicate which patients are likely to die and which may be severely disabled, according to a study led by the University of California, San Francisco, the University of Pennsylvania and the University of Michigan.
-
Academic News RESCUE BT trial results published in JAMA journal!
Time of Update: 2022-08-20
A multicenter, randomized, placebo-controlled, double-blind clinical trial of intravenous tirofiban before endovascular therapy for acute large vessel occlusion (RESCUE BT) was conducted by the Department of Neurology, Second Affiliated Hospital of Army Medical University (Chongqing Xinqiao Hospital) The team of Professor Yang Qingwu and Professor Zi Wenjie of the Medical Center cooperated with 54 hospitals across the country.
-
Cell sub-issue: Why does using your brain make you feel tired?
Time of Update: 2022-08-20
Three years ago, research by Mathias Pessiglione's team, also published in Current Biology, showed that excessive exercise can also lead to mental fatigue, causing a decrease in activity including in the prefrontal cortex of the brain, an area critical for decision-making .
-
Nature's dopamine subsystem senses water intake information
Time of Update: 2022-08-20
In conclusion, the authors found that dopamine neurons located in the ventral tegmental area of the midbrain are activated during certain stages of the body's food and water digestion and absorption .
-
Nat Neurosci︱Yuan Wen et al reveal a new regulatory mechanism of neuronal maturation in the neocortex
Time of Update: 2022-08-20
On August 1, 2022, researcher Yuan Wen from Shenzhen Bay Laboratory and Professor Paola Arlotta's laboratory at Harvard University published an article titled Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex online in Nature Neuroscience.
-
Neuron Xiao Bailong's team reveals the important function of the mechanical force receptor Piezo1 in the mechanical force perception of the central nervous system
Time of Update: 2022-08-20
Editor in charge |On August 12, 2022, Xiao Bailong's team from the School of Pharmacy, Tsinghua University published a paper entitled Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions (Piezo1 mediates astrocyte mechanical signaling and regulates adult hippocampus) in the journal Neuron.
-
Nat. Commun Hou Yingyong/Ding Chen/He Fuchu team collaborated to release a proteomic map of squamous cell carcinoma in Chinese population, revealing molecular differences between squamous cell carcinoma and adenocarcinoma
Time of Update: 2022-08-19
Recently, Hou Yingyong's team from Zhongshan Hospital Affiliated to Fudan University, Ding Chen's team from Fudan University's Human Phenotype Research Institute and He Fuchu's team from Beijing Institute of Life Sciences jointly published a paper entitled "Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas" in Nature Communications across multiple tissues" article .
-
A brief analysis of the key points of the progress of dementia and Alzheimer's disease
Time of Update: 2022-08-19
Guideline name: Brief analysis of the key points of dementia and Alzheimer's disease progressionEnglish title:Publisher: West China Hospital of Sichuan UniversityRelease date: 2022-07-26brief introduc
-
Circulation: Exercise this number per week with the lowest risk of death
Time of Update: 2022-08-19
Coincidentally, in a recent study published on Circulation, entitled "Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults", more than 100,000 people were Combined, the researchers explored the association between exercise duration and risk of death .
-
European Radiology: The value of CTP in regional classification of ischemic stroke
Time of Update: 2022-08-19
Clinically, the improved classification is beneficial for the screening of different treatment plans for acute ischemic stroke patients, and the probability map can provide an improved and standardized classification method for ischemic areas in CTP stroke imaging .
-
Neurology case: Valproic acid-induced reversible hemilateral choreoathetosis in a patient with Rasmussen encephalitis
Time of Update: 2022-08-19
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view A 24-year-old woman diagnosed with Rasmussen encephalitis at age 6 was examined for involuntary movements .
-
A 10-year follow-up study of over 200,000 Asians: "Poverty" and "Top"!
Time of Update: 2022-08-19
In this study, low income was an important risk factor for the simultaneous diagnosis of major MetS components and stroke .
In this study, low income was an important risk factor for the simultaneous diagnosis of major MetS components and stroke .
