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Neurology: Relationships between gender, menopause, and white matter hyperintensity: a Rhineland study
Time of Update: 2022-09-06
Recently, a study published in Neurology sought to investigate these sex differences and age-dependent WMH burden across the adult lifespan and examine the impact of menopause .
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Annals of neurology: the relationship between the human blood metabolome and Alzheimer's disease risk
Time of Update: 2022-09-06
Therefore, we also performed Phe-MR analysis on 679 disease features to predict potential target-mediated side effects associated with metabolite intervention to comprehensively assess their clinical safety .
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Neurology: Long-term efficacy of ponimod in the treatment of relapsing-remitting multiple sclerosis
Time of Update: 2022-09-06
0000000000200606 A recent study published in the journal Neurology assessed the dose-response relationship and wavelet of 10, 20, and 40 mg of ponimod using a combined data analysis of the Phase 2 core and extension studies in patients with relapsing multiple sclerosis (RRMS).
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Why does my heart skip a beat after drinking too much coffee?
Time of Update: 2022-09-06
Caffeine increases the brain's ability to receive dopamine .
Caffeine increases the brain's ability to receive dopamine .
Caffeine increases the brain's ability to receive dopamine .
Caffeine increases the brain's ability to receive dopamine .
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A common symptom of neurological disorders - vertigo
Time of Update: 2022-09-06
It often occurs suddenly, with dizziness reaching its most severe at the beginning, exacerbating head movement and opening of the eyes, often accompanied by dumping, panic due to a strong sense of rotation and movement, accompanied by tinnitus, deafness, nausea, vomiting, pallor, slow pulse, decreased blood pressure, and nystagmus.
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Epileptic encephalopathy with mutations in the KCNT1 gene: signs and symptoms, etiology, epidemiology, diagnosis and treatment
Time of Update: 2022-09-06
4. EpidemiologyOf the 175 cases of early-onset epileptic encephalopathy diagnosed and treated in the Pediatric Neurological Clinic and Ward of Peking University First Hospital, 6 cases of KCNT1 mutation-related epilepsy were confirmed, often showing infantile epilepsy accompanied by wandering focal seizures.
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AM by Jörg Lahann's team at the Karlsruhe Institute of Technology in Germany: Deep learning-assisted stratification of β amyloid mutants using a dried droplet pattern
Time of Update: 2022-09-06
Recently, Jörg Lahann's team from the Karlsruhe Institute of Technology in Germany published a research paper on Advanced Materials, using a pre-trained deep learning algorithm to analyze the structural characteristics of pathogenic β amyloid according to the sedimentary pattern left by dried droplets, achieving very high prediction accuracy.
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Cerebral Cortex: Using grey matter and amyloid data to study multiple linker changes in Alzheimer's disease
Time of Update: 2022-09-06
1. Multiplex network analysis is helpful to detect differences in AD at different stages, overlapping connection strength is sensitive to changes occurring in CN Aβ+ and MCI Aβ+ subjects as their amyloid covariance networks are undergoing more dynamic changes, The multivariate pathway revealed a third temporal module in MCI aβ+ subjects, possibly reflecting the transition to AD dementia .
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[The Lancet] Heart-Brain Unity: Cardiovascular Health Predicts Brain Aging
Time of Update: 2022-09-06
Specifically, the scientists looked at the association of brain PAD with five outcomes: measures of childhood, midlife, and later life; imaging-based markers of neurodegeneration, including Alzheimer's disease and cerebrovascular disease; cognitive performance; blood-based biomarkers; and subsequent rates of brain atrophy .
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Science demonstrates potential therapies for Down syndrome that improve cognitive function in 6 months
Time of Update: 2022-09-06
Resources:[1] A therapy found to improve cognitive function in patients with Down syndrome.
Resources:[1] A therapy found to improve cognitive function in patients with Down syndrome.
abq4515Resources:[1] A therapy found to improve cognitive function in patients with Down syndrome.
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Annals of neurology: Cerebral amyloid angiopathy associated with hematoma expansion
Time of Update: 2022-09-06
CAA prevalence of ICH), to determine associations with HE and functional outcomes, and to assess the interaction between ICH type and baseline hematoma volume, time after symptom onset, and tranexamic acid treatment and outcome .
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Science cover!
Time of Update: 2022-09-06
Here, we identify an injury-induced cluster of ependymal glial cells at the wound site as a potential population of progenitor cells to replenish lost neurons through a cellular state transition process similar to neurogenesis during development .
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ESC 2022: Milvexian reduces ischemic stroke risk without increasing bleeding risk (AXIOMATIC-SSP study)
Time of Update: 2022-09-06
In the intended population, nearly all doses of milvexian (except 200 mg twice daily) were shown to numerically reduce the risk of ischemic stroke (except for occult stroke) .
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Autoimmune encephalitis: signs and symptoms, etiology, epidemiology, diagnosis and treatment
Time of Update: 2022-09-06
Diagnostic conditions include four aspects: clinical manifestations, auxiliary examinations, confirmatory tests, and exclusion of other causes.
Diagnostic conditions include four aspects: clinical manifestations, auxiliary examinations, confirmatory tests, and exclusion of other causes.
Diagnostic conditions include four aspects: clinical manifestations, auxiliary examinations, confirmatory tests, and exclusion of other causes.
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KCNB1 Encephalopathy: signs and symptoms, etiology, epidemiology, diagnosis, and treatment
Time of Update: 2022-09-06
See: KCNQ2 gene-associated epilepsy: symptoms and signs, etiology, epidemiology, diagnosis, and treatmentSome patients with KCNB1 encephalopathy may also be diagnosed with Lennox-Gastaut syndrome (LGS).
See: KCNQ2 gene-associated epilepsy: symptoms and signs, etiology, epidemiology, diagnosis, and treatmentSome patients with KCNB1 encephalopathy may also be diagnosed with Lennox-Gastaut syndrome (LGS).
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Neurology: Quantitative diffusion-weighted MRI neuroimaging strongly associated with outcomes after pediatric cardiac arrest
Time of Update: 2022-09-06
The significance of this study is its finding that quantitative diffusion thresholds on MRI within 7 days of cardiac arrest are associated with adverse outcomes in children .
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JAMA sub-issue: Professor Gao Xiang found that eating right and exercising can reduce the death rate of Parkinson's by half!
Time of Update: 2022-09-06
Parkinson's patients eat more whole grains, vegetables, fruits, beans and nuts, eat less red and processed meat; walk 10-20 hours a week or do moderate-intensity exercise for 5-9 hours, and the mortality rate can be reduced by 49% .
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JAMA Neurology: A clinical study of Tau-PET protein imaging for prediction of Alzheimer's disease based on biomarkers
Time of Update: 2022-09-06
AD: Alzheimer's diseaseAβ: β-amyloidA/T/NBiomarkers: Biomarkers associated with beta-amyloid deposition/pathological tau/neurodegenerationCU: Cognitive Impairment EBM: Event-Based ModelingMCI: Mild Cognitive ImpairmentPET: Positron Emission TomographySUVR: Normalized Uptake Value RatiobackgroundLongitudinal tau protein aggregation in the brain in different clinical stages of Alzheimer's disease (AD) is a research hotspot in the current field.
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LANCET HEALTHY LONGEVITY: Is the brain healthy, look at the brain-PAD indicator
Time of Update: 2022-09-06
Specifically, the association of brain-PAD with five outcomes was investigated: measures of life course in childhood, middle age, and later life; imaging-based markers of neurodegeneration, including Alzheimer's disease and cerebrovascular disease; cognition capacity; blood biomarkers; and subsequent rates of brain atrophy .
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Amyotrophic lateral sclerosis: symptoms and signs, etiology, epidemiology, diagnosis, and treatment
Time of Update: 2022-09-06
Lower motor neuron disease can lead to muscle weakness and wasting (atrophy), decreased muscle tone, weakened reflexes (hyporeflexia), twitching of muscle fibers (muscle bundle tremor), muscle spasms, and abnormalities of speech, swallowing, and breathing.
